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Highlights

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Fleming is happy to announce the establishment of DrugTrek, a micro small-to-medium enterprise (SME) spinoff of Fleming and Uni-Pharma, focusing on the research and development of antifibrotic therapies.

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Research by Emmanouil et al from the Dimas lab reveals rapid and extensive remodelling of the human gut microbiome following short term dietary restriction of animal products, and uncovers associations with host molecular phenotypes.

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Fleming researchers have uncovered a novel role for fibroblast-expressed Versican, a multifunctional ECM proteoglycan, as an autologous fibrotic brake that suppresses pulmonary fibrosis.

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Research by Sofia Papanikolaou at the Nikolaou lab, uncovers a new role of the genome organizer SMC1A in Systemic Lupus Erythematosus.

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Research by Niki Chalkidi and Athanasia Stavropoulou at the Koliaraki Lab reveals that Notch3 regulates pericyte phenotypic plasticity in colorectal cancer.

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Fleming's Technology Transfer Office (TTO) is happy to announce the granting of an international (PCT) patent application, the very first of BSRC Fleming, on Autotaxin inhibitors for the treatment of Idiopathic Pulmonary Fibrosis (IPF) in Europe.

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A new study by the Dimas lab has shown that short-term dietary restriction of animal products alters metabolic profiles and modulates immune function, with changes in a direction suggesting mostly positive effects on health.

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New Research by Z. Faidon Brotzakis from Skretas Lab on Identification of potent high-affinity secondary nucleation inhibitors of Aβ42 aggregation from an ultra-large chemical library using deep docking.

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Research from the Verykokakis lab revealed that NKT cells can act as a “double-edged sword” in liver cancer, contributing to tumor formation early on, but helping to slow tumor growth at later stages.

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Moulos lab participates in the first chromosome-level genome assembly of the Vermilion Snapper fish.

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Research by Kleio-Maria Verrou et al. at the Nikolaou lab presents a novel machine-learning method to distinguish autoimmune from infectious diseases from whole-blood transcriptomes.

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Reczko group was awarded 1st and 2nd places in the BioASQ 2025 international competition.

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Research led by the Kafasla lab reveals that alternative splicing (AS) deregulation in Pancreatic Neuroendocrine Tumors results in neuronal phenotype and disrupted hormone secretion.

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Vasileios Ntafis as the Vice-President of International Affairs of the Federation of European Laboratory Animal Associations (FELASA).

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Research from the Skretas Lab Optimizes a High-Throughput Screen for Monitoring Disease-Associated Protein Misfolding and Aggregation in Bacteria.

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New Research by Z. Faidon Brotzakis from Skretas Lab on Targeting AR-V7 Structural Dynamics via Deep Ensemble Docking.

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Research by Antonis Klonizakis et al. at the Nikolaou lab uncovers a hidden layer of complexity in mammalian gene regulation and hints at the existence of "negative enhancer" elements.

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Research by Rouskas, Bocher et al from the Dimas lab reveals extensive metabolic reprogramming following restriction of animal products with effects on cardiometabolic health.

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Research from Lida Iliopoulou et al. at the Kollias lab uncovers how distinct fibroblast subtypes spatially regulate intestinal inflammation via TNFR1 signaling.

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Skretas lab introduces ProteoSeeker: A Novel Tool Accelerating Protein Discovery Through Accessible Metagenomic Analysis.

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New research by Z.Faidon Brotzakis from Skretas Lab concerning the structural dynamics of disordered proteins.

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Exciting News from Our Proteomics Facility!

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Unraveling Life’s Code: Tsoumakidou Lab at the SCIENCE DAY "PHYSICS FAIR".

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New research by Z.Faidon Brotzakis from Skretas Lab concerning the structural dynamics of the Aβ42 Amyloid Filaments in Alzheimer's Disease.

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