The scientists at BSRC “Alexander Fleming” perform cutting-edge research, aiming to understand molecular mechanisms of complex biological processes in health and disease. We are also committed to contribute to innovation in medicine, by developing novel therapeutic and diagnostic methods, focusing on immunity and inflammation, cancer, and neurodegenerative diseases. To keep our focus on top-notch research, we recruit at all levels with excellence as the sole criterion and we support our researchers by providing state-of-the science infrastructures and a pleasant working environment. FLEMING is a non-profit organization operating under the auspices of the Greek General Secretariat for Research & Technology and is supported by the Greek government and by national, European and international grants.
Highlights
The Inauguration of the "Center for New Biotechnologies & Precision Medicine" was announced at a press conference held on 07.06.2018 at the University of Athens. Fleming is a key collaborating Institute in this initiative and partner of pMedGR, the Greek Research Infrastructure for Personalised Medicine, which forms the basis of the New Center.
In a recent study published in PNAS, PhD student Ana Henriques from the labs of Dr. George Kollias and Dr. Vasiliki Koliaraki revealed that the kinase MK2 through the activation of Hsp27 in intestinal mesenchymal cells/CAFs plays an essential role in the promotion of colorectal cancers. [Pubmed].
Expanding previous work on the role of autotaxin in chronic inflammatory disorders that has provided the scientific basis for phase IIb clinical trials in idiopathic pulmonary fibrosis, Fleming researchers have now uncovered a role for this secreted lysophospholipase D in the pathogenesis of lung cancer [PubMed].
Fleming researchers, using a Spondyloarthritis (SpA) mouse model have found that Tnfr2 signaling is regulating polyarthritis and a newly identified heart valve stenosis, which is a common comorbidity of SpA in human patients. [PubMed], [JCI Highlight].
NEWS AND EVENTS
26/06/2018
Seminar 26/06/2018, 12.30. "Host-microbiome interactions at the oral mucosal barrier", Niki Moutsopoulos, DDS, PhD, Clinical Investigator, Oral Immunity & Infection Unit, National Institute of Dental & Craniofacial Research (NIDCR), National Institutes of Health, Bethesda, MD, United States.
PUBLICATIONS
Visit BSRC Fleming's scientific Publications web page
FUNDING
Visit BSRC Fleming's funding web page
B.S.R.C. "Alexander Fleming" 34 Fleming Street, 16672 Vari, Greece Contact us
