The scientists at BSRC “Alexander Fleming” perform cutting-edge research, aiming to understand molecular mechanisms of complex biological processes in health and disease. We are also committed to contribute to innovation in medicine, by developing novel therapeutic and diagnostic methods, focusing on immunity and inflammation, cancer, and neurodegenerative diseases. To keep our focus on top-notch research, we recruit at all levels with excellence as the sole criterion and we support our researchers by providing state-of-the science infrastructures and a pleasant working environment. FLEMING is a non-profit organization operating under the auspices of the Greek General Secretariat for Research & Technology and is supported by the Greek government and by national, European and international grants.
Highlights
OPEN CALL for applications for 2 Director positions for the newly inaugurated Institutes at the BSRC Fleming: the Institute for Basic Biomedical Research and the Institute for Bioinnovation. Deadline for applications: 6 May 2019.
Koliaraki et al. from the Kollias and Koliaraki labs demonstrate that innate sensing through mesenchymal TLR4/MyD88 signals promotes spontaneous intestinal tumorigenesis. Genetic deletion of TLR4 or MyD88 in IMCs led to altered molecular profiles and reduction of intestinal tumors in the APCmin model. [Pubmed]
Christodoulou-Vafeiadou and Ioakeimidis et al. in the Kontoyiannis lab showed that the ubiquitous RNA binding protein HuR has divergent roles in intestinal epithelial cells and myeloid-derived immune compartment in various models of intestinal inflammation and cancer. [PubMed]
Semelidou et al from the Skoulakis lab demonstrated that distinct neuronal circuits mediate olfactory habituation latency and induction and proposed a novel role for the Lateral Horn, a neuropil innately encoding response valence to odor stimuli, in this process. [Pubmed]
NEWS AND EVENTS
19-23/05/2019
EMBO Workshop "Mesenchymal cells in inflammation, immunity and cancer" | 19-23 May 2019 | Athens, Greece.
29/03/2019
Seminar 29/03/2019, 13:00. "Enteric Nervous System: Intrinsic Programs and Environmental Interactions", Dr. Vassilis Pachnis, Development and Homeostasis of the Nervous System Laboratory, The Francis Crick Institute.
27/03/2019
Seminar 27/03/2019, 13:00."Sex Differences in Neuropsychopharmacology: insights from animal models of depression", Christina Dalla, PhD, Associate Professor of Pharmacology, President of the Hellenic Society for Neuroscience, Medical School, National & Kapodistrian University of Athens.
PUBLICATIONS
Visit BSRC Fleming's scientific Publications web page
FUNDING
Visit BSRC Fleming's funding web page
B.S.R.C. "Alexander Fleming"
34 Fleming Street, 16672 Vari, Greece
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