The scientists at BSRC “Alexander Fleming” perform cutting-edge research, aiming to understand molecular mechanisms of complex biological processes in health and disease. We are also committed to contribute to innovation in medicine, by developing novel therapeutic and diagnostic methods, focusing on immunity and inflammation, cancer, and neurodegenerative diseases. To keep our focus on top-notch research, we recruit at all levels with excellence as the sole criterion and we support our researchers by providing state-of-the science infrastructures and a pleasant working environment. FLEMING is a non-profit organization operating under the auspices of the Greek General Secretariat for Research & Technology and is supported by the Greek government and by national, European and international grants.

Highlights

06/11/2019
06 November 2019

Glentis et al., from the Dimas lab, uncover genetic risk variants for hereditary breast cancer in the first exome sequencing study to be conducted in the Greek population. The authors carried out exome sequencing on BSRC Alexander Fleming’s in-house NGS platform, in patients with hereditary breast cancer of unknown genetic aetiology and in their informative relatives. [Pubmed]

29/10/2019
29 October 2019

Custom bioinformatics analysis performed by Dr. Martin Reczko contributed to a new collaborative study that introduces a platform for bacterial production and direct functional screening of expanded molecular libraries for discovering inhibitors of protein aggregation, associated with a wide range of human disorders, including Alzheimer’s and Parkinson’s disease. [Science Advances]

15/10/2019
15 October 2019

In a new publication from the Skoulakis lab in the Journal of Neuroscience, Roussou et al  provides conceptual, but also pharmacological links between habituation defects in Drosophila and particular schizophrenia symptoms in humans. [Pubmed]

08/10/2019
08 October 2019

Denaxa et al., describes how to genetically engineer young neurons, transplant them into the brain and study their impact on brain function. These methodologies are powerful tools for the design of cell transplantation therapies and exploring mechanisms of neurodevelopmental diseases. [Pubmed]

NEWS AND EVENTS

14/11/2019

Seminar 14/11/2019, 12:00. "Organ-Chips: micro engineered platforms for studying human biology", Katia Karalis, MD, PhD, Executive Vice President of Research, "Emulate Inc.", Boston, USA.

20/11/2019

Seminar 20/11/2019, 13.00. "Immune regulation of metabolic homeostasis", Antonios Chatzigeorgiou, MD, PhD, Assistant Professor of Physiology, Medical School, University of Athens.

PUBLICATIONS

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FUNDING

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B.S.R.C. "Alexander Fleming"
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