The scientists at BSRC “Alexander Fleming” perform cutting-edge research, aiming to understand molecular mechanisms of complex biological processes in health and disease. We are also committed to contribute to innovation in medicine, by developing novel therapeutic and diagnostic methods, focusing on immunity and inflammation, cancer, and neurodegenerative diseases. To keep our focus on top-notch research, we recruit at all levels with excellence as the sole criterion and we support our researchers by providing state-of-the science infrastructures and a pleasant working environment. FLEMING is a non-profit organization operating under the auspices of the Greek General Secretariat for Research & Technology and is supported by the Greek government and by national, European and international grants.
Highlights
Marietta Armaka from BSRC Alexander Fleming, Geert Van Loo (VIB, Ghent) and Manolis Pasparakis (Uni. Cologne, co-ordinator) supervised a study published in Nature Cell Biology which identifies a new molecular mechanism causing rheumatoid arthritis. [Nature Cell Biology]
Kerdidani et al. from Tsoumakidou lab demonstrated that the Wnt1 oncoprotein signals paracrine on dendritic cells to silence chemokine genes and promote tumor immune escape. In vivo RNA interference against Wnt1 activated anti-tumor immunity and halted tumor growth. [Pubmed]
OPEN CALL for applications for 2 Director positions for the newly inaugurated Institutes at the BSRC Fleming: the Institute for Basic Biomedical Research and the Institute for Bioinnovation. Deadline for applications: 6 May 2019.
Koliaraki et al. from the Kollias and Koliaraki labs demonstrate that innate sensing through mesenchymal TLR4/MyD88 signals promotes spontaneous intestinal tumorigenesis. Genetic deletion of TLR4 or MyD88 in IMCs led to altered molecular profiles and reduction of intestinal tumors in the APCmin model. [Pubmed]
NEWS AND EVENTS
31/05/2019
Seminar 31/05/2019, 13:00. "Regulatory cells in tumor immune evasion", Panagiotis Verginis, PhD, Investigator - Assistant Professor Level, Center of Immunology and Transplantation, Biomedical Research Foundation Academy of Athens.
03/06/2019
Seminar 03/06/2019, 13:00. "Gene regulation networks in neural development", Panos Politis, Researcher C, Center for Basic Research, Biomedical Research Foundation of the Academy of Athens.
PUBLICATIONS
Visit BSRC Fleming's scientific Publications web page
FUNDING
Visit BSRC Fleming's funding web page
B.S.R.C. "Alexander Fleming"
34 Fleming Street, 16672 Vari, Greece
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