RNA Biology & Epigenetics

The RNA biology and Epigenetics Program aims to advance knowledge on the mechanisms driving regulation of gene expression at the transcriptional, post-transcriptional and epigenetic levels, using cutting-edge molecular biology and biochemical approaches, including high-throughput functional assays and single-cell NGS technologies, transgenic systems, animal models of disease and patient-derived material. We are endeavouring to elucidate these molecular regulatory mechanisms at the fundamental level, but also to understand how their perturbation is involved in the development and progression of inflammatory disorders, degenerative diseases, and cancer. We also aim towards translational exploitation of our results for the development of diagnostic tools and therapies targeting the relevant essential regulatory processes.

Current member researchers of the Program:

A. Dimas -
M. Fousteri - Regulatory (epi)genomics in cancer and aging related diseases
P. Hatzis - RNA-mediated transcriptional and epigenetic regulation in carcinogenesis
P. Kafasla - Nuclear Ribonucleoprotein complexes (RNPs) in immune response and cancer
D. Kontoyiannis - Post-transcriptional modules of gene expression in physiology and disease

 

 

 

B.S.R.C. "Alexander Fleming"
34 Fleming Street, 16672 Vari, Greece
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