Publications

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Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, Frommelt LS, Qu R, Knapp MS, Henriques A, Chalkidi N, Koliaraki V, Jiao J, Brewer JR, Bacher M, Blackburn HN, Zhao X, Breyer RM, Aidinis V, Jain D, Su B, Herschman HR, Kluger Y, Kollias G, Flavell RA. 2020, "Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche", Nature, 580(7804) :524-529 [PubMed].

Ninou I, Sevastou I, Magkrioti C, Kaffe E, Stamatakis G, Thivaios S, Panayotou G, Aoki J, Kollias G, Aidinis V. 2020, "Genetic deletion of Autotaxin from CD11b+ cells decreases the severity of experimental autoimmune encephalomyelitis.", PLoS One, 15(4) :e0226050 [PubMed].

Gerokonstantis DT, Nikolaou A, Magkrioti C, Afantitis A, Aidinis V, Kokotos G, Moutevelis-Minakakis P. 2020, "Synthesis of novel 2-pyrrolidinone and pyrrolidine derivatives and study of their inhibitory activity against autotaxin enzyme", Bioorg Med Chem. , Jan 15; 28(2):115216. [PubMed].

Nikitopoulou I, Manitsopoulos N, Kotanidou A, Tian X, Petrovic A, Magkou C, Ninou I, Aidinis V, Schermuly RT, Kosanovic D, Orfanos SE. 2019, "Orotracheal treprostinil administration attenuates bleomycin induced lung injury, vascular remodeling, and fibrosis in mice", Pulm Circ. , 2019 Nov 15; 9(4):204589401988195 [PubMed].

Kaffe E, Magkrioti C, Aidinis V. 2019, "Deregulated Lysophosphatidic Acid Metabolism and Signalling in Liver Cancer", Cancers, 2019 Oct 23; 11(11). pii: E1626 [PubMed].

Tzouvelekis A, Eickelberg O, Kaminski N, Bouros D, Aidinis V. 2019, "Pulmonary Fibrosis", Frontiers Media SA. [Google Books].

Xylourgidis N, Min K, Ahangari F, Yu G, Herazo-Maya JD, Karampitsakos T, Aidinis V, Binzenhöfer L, Bennett AM, Kaminski N, Tzouvelekis A. 2019, "Role of Mitogen activated-kinase (MAPK)-phosphatase (MKP)-5 in pulmonary fibrosis", Am J Physiol Lung Cell Mol Physiol, 2019 Sep 4 [PubMed].

Magkrioti C, Galaris A, Kanellopoulou P, Stylianaki EA, Kaffe E, Aidinis V. 2019, "Autotaxin and chronic inflammatory diseases", J Autoimmun., 2019 Aug 27: 102327 [PubMed].

Spella M, Lilis I, Pepe MA, Chen Y, Armaka M, Lamort AS, Zazara DE, Roumelioti F, Vreka M, Kanellakis NI, Wagner DE, Giannou AD, Armenis V, Arendt KA, Klotz LV, Toumpanakis D, Karavana V, Zakynthinos SG, Giopanou I, Marazioti A, Aidinis V, Sotillo R, Stathopoulos GT. 2019, "Club cells form lung adenocarcinomas and maintain the alveoli of adult mice", Elife., 2019 May 29. ;8 [PubMed].

Matralis AN, Afantitis A, Aidinis V. 2019, "Development and therapeutic potential of autotaxin small molecule inhibitors: From bench to advanced clinical trials", Med Res Rev., 2019 May; 39(3):976-1013 [PubMed].

Tzilas V, Bouros E, Barbayianni I, Karampitsakos T, Kourtidou S, Ntassiou M, Ninou I, Aidinis V, Bouros D, Tzouvelekis A. 2019, "Vitamin D prevents experimental lung fibrosis and predicts survival in patients with idiopathic pulmonary fibrosis", Pulm Pharmacol Ther, 2019 Apr; 55:17-24. [PubMed].

Ninou I, Kaffe E, Müller S, Budd DC, Stevenson CS, Ullmer C, Aidinis V. 2018, "Pharmacologic targeting of the ATX/LPA axis attenuates bleomycin-induced pulmonary fibrosis", Pulm Pharmacol Ther, 2018 Oct; 52:32-40 [PubMed].

D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC. 2018, "Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism", J Lipid Res, 2018 Oct; 59(10):1805-1817 [PubMed].

Barbayianni I, Ninou I, Tzouvelekis A, Aidinis V. 2018, "Bleomycin Revisited: A Direct Comparison of the Intratracheal Micro-Spraying and the Oropharyngeal Aspiration Routes of Bleomycin Administration in Mice", Front Med, 2018 Sep 24; 5:269 [PubMed].

Ninou I, Magkrioti C, Aidinis V. 2018, "Autotaxin in Pathophysiology and Pulmonary Fibrosis", Front Med, 2018 Jun 13; 5:180 [PubMed].

Tzouvelekis A, Toonkel R, Karampitsakos T, Medapalli K, Ninou I, Aidinis V, Bouros D, Glassberg MK. 2018, "Mesenchymal Stem Cells for the Treatment of Idiopathic Pulmonary Fibrosis", Front Med, 2018 May 15; 5:142 [PubMed].

Magkrioti C, Oikonomou N, Kaffe E, Mouratis MA, Xylourgidis N, Barbayianni I, Megadoukas P, Harokopos V, Valavanis C, Chun J, Kosma A, Stathopoulos GT, Bouros E, Bouros D, Syrigos KN, Aidinis V. 2018, "The autotaxin - lysophosphatidic acid axis promotes lung carcinogenesis", Cancer Res. , 2018 May 3. pii: canres.3797.2017. doi: 10.1158/0008-5472.CAN-17-3797. [Epub ahead of print] [PubMed].

Nikolaou A, Ninou I, Kokotou MG, Kaffe E, Afantitis A, Aidinis V, Kokotos G. 2018, "Hydroxamic Acids Constitute a Novel Class of Autotaxin Inhibitors that Exhibit in Vivo Efficacy in a Pulmonary Fibrosis Model.", J Med Chem, 2018 Apr 18 [PubMed].

Papaioannou O, Karampitsakos T, Barbayianni I, Chrysikos S, Xylourgidis N, Tzilas V, Bouros D, Aidinis V, Tzouvelekis A. 2018, "Metabolic Disorders in Chronic Lung Diseases.", Front Med , 2018 Jan 18; 4:246 [PubMed].

Tashiro J, Rubio GA, Limper AH, Williams K, Elliot SJ, Ninou I, Aidinis V, Tzouvelekis A, Glassberg MK. 2017, "Exploring Animal Models That Resemble Idiopathic Pulmonary Fibrosis.", Front Med, 2017 Jul 28; 4:118 [PubMed].

Tzouvelekis A, Bouros D, Aidinis V. 2017, "Biomarkers in Idiopathic Pulmonary Fibrosis: A RAGE-ing Bull in the Arena", Ann Am Thorac Soc., 2017 May; 14(5):613-614 [PubMed].

Karampitsakos T, Tzilas V, Tringidou R, Steiropoulos P, Aidinis V, Papiris SA, Bouros D, Tzouvelekis A. 2017, "Lung cancer in patients with idiopathic pulmonary fibrosis", Pulm Pharmacol Ther., 2017 Apr 1 [PubMed].

Tomos IP, Tzouvelekis A, Aidinis V, Manali ED, Bouros E, Bouros D, Papiris SA. 2017, "Extracellular matrix remodeling in idiopathic pulmonary fibrosis. It is the 'bed' that counts and not 'the sleepers’", Expert Rev Respir Med, 2017 Mar 8 :1-11. [PubMed].

Tzouvelekis A, Yu G, Lacks Lino Cardenas C, Herazo-Maya JD, Wang R, Woolard T, Zhang Y, Sakamoto K, Lee H, Yi JS, DeIuliis G, Xylourgidis N, Ahangari F, Lee PJ, Aidinis V, Herzog EL, Homer R, Bennett AM, Kaminski N. 2017, "SH2 Domain-containing Phosphatase-SHP-2 is a Novel Anti-fibrotic Regulator in Pulmonary Fibrosis", Am J Respir Crit Care Med., 2017 Feb 15; 195(4):500-514. [PubMed].

Anas AA, Claushuis TA, Mohan RA, Christoffels VM, Aidinis V, Florquin S, Van't Veer C, Hou B, de Vos AF, van der Poll T. 2017, "Epithelial Myeloid-differentiation Factor 88 is Dispensable During Klebsiella Pneumonia", Am J Respir Cell Mol Biol., 2017 Feb 10. [PubMed].

Tzouvelekis A, Tzilas V, Papiris S, Aidinis V, Bouros D. 2017, "Diagnostic and prognostic challenges in Idiopathic Pulmonary Fibrosis A patient "Q and A" approach", Pulm Pharmacol Ther., 2017 Feb; 42:21-24. [PubMed].

Kaffe E, Katsifa A, Xylourgidis N, Ninou I, Zannikou M, Harokopos V, Foka P, Dimitriadis A, Evangelou K, Moulas AN, Georgopoulou U, Gorgoulis VG, Dalekos GN, Aidinis V. 2016, "Hepatocyte Autotaxin expression promotes liver fibrosis and cancer", Hepatology, 2016 Dec 16. [PubMed].

Vrontaki E, Melagraki G, Kaffe E, Mavromoustakos T, Kokotos G, Aidinis V, Afantitis A. 2016, "Computer Aided Drug Design Approaches for Identification of Novel Autotaxin (ATX) Inhibitors.", Curr Med Chem., 2016;23(17) :1708-24 [PubMed].

Filippou P, Antoniou C, Obata T, Van Der Kelen K, Harokopos V, Kanetis L, Aidinis V, Van Breusegem F, Fernie AR, Fotopoulos V. 2016, "Kresoxim-methyl primes Medicago truncatula plants against abiotic stress factors via altered reactive oxygen and nitrogen species signalling leading to downstream transcriptional and metabolic readjustment", J Exp Bot., 2016 Mar; 67(5):1259-74. [PubMed].

Katsifa A, Kaffe E, Nikolaidou-Katsaridou N, Economides AN, Newbigging S, McKerlie C, Aidinis V. 2015, "The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life", PLoS One., 2015 Nov 16; 10(11). [PubMed].

Mouratis MA, Magkrioti C, Oikonomou N, Katsifa A, Prestwich GD, Kaffe E, Aidinis V. 2015, "Autotaxin and Endotoxin-Induced Acute Lung Injury", PLoS One. , 2015 Jul 21; 10(7):e0133619 [PubMed].

Giannou AD, Marazioti A, Spella M, Kanellakis NI, Apostolopoulou H, Psallidas I, Prijovich ZM, Vreka M, Zazara DE, Lilis I, Papaleonidopoulos V, Kairi CA, Patmanidi AL, Giopanou I, Spiropoulou N, Harokopos V, Aidinis V, Spyratos D, Teliousi S, Papadaki H, Taraviras S, Snyder LA, Eickelberg O, Kardamakis D, Iwakura Y, Feyerabend TB, Rodewald HR, Kalomenidis I, Blackwell TS, Agalioti T, Stathopoulos GT. 2015, "Mast cells mediate malignant pleural effusion formation.", J Clin Invest. , 2015 Apr 27. pii: 79840. doi: 10.1172/JCI79840. [Epub ahead of print] [PubMed].

Greenman R, Gorelik A, Sapir T, Baumgart J, Zamor V, Segal-Salto M, Levin-Zaidman S, Aidinis V, Aoki J, Nitsch R, Vogt J, Reiner O. 2015, "Non-cell autonomous and non-catalytic activities of ATX in the developing brain", Front Neurosci., 2015 Mar 4; 9:53 [PubMed].

Barbayianni E, Kaffe E, Aidinis V , Kokotos G. 2015, "Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer", Prog Lipid Res., 2015 Feb 20. pii: S0163-7827(15)00011-9. doi: 10.1016/j.plipres.2015.02.001. [Epub ahead of print] [PubMed].

Roulis M, Nikolaou C, Kotsaki E, Kaffe E, Karagianni N, Koliaraki V, Salpea K, Ragoussis J, Aidinis V, Martini E, Becker C, Herschman HR, Vetrano S, Danese S, Kollias G. 2014, "Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis", Proc Natl Acad Sci U S A. , 2014 Oct 28; 111(43):E4658-67. doi: 10.1073/pnas.1415762111. Epub 2014 Oct 14. [PubMed].

Nikolaidis C, Bouros E, Tzouvelekis A, Drakopanagiotakis F, Ntolios P, Kaltsas K, Boglou P, Anevlavis S, Steiropoulos P, Lambropoulou M, Mikroulis D, Kolios G, Aidinis V, Bouros D. 2014, "A biobank for Interstitial Lung Diseases according to the European Network EurIPF and ΒΒΜRI", Pneumon, vol 27(3) 209-213. [PDF].

Magkrioti C, Aidinis V. 2013, "Autotaxin and lysophosphatidic acid signalling in lung pathophysiology.", World J Respirol. , 2013 November 28; 3(3): 77-103. [PDF]

Park GY, Lee YG, Berdyshev E, Nyenhuis S, Du J, Fu P, Gorshkova IA, Li Y, Chung S, Karpurapu M, Deng J, Ranjan R, Xiao L, Jaffe HA, Corbridge SJ, Kelly EA, Jarjour NN, Chun J, Prestwich GD, Kaffe E, Ninou I, Aidinis V ,Morris AJ, Smyth SS, Ackerman SJ, Natarajan V, Christman JW. 2013, "Autotaxin production of Lysophosphatidic Acid Mediates Allergic Asthmatic Inflammation.", Am J Respir Crit Care Med. , 2013 Sep 19. [Epub ahead of print] [PubMed]

Vassiliou AG, Maniatis NA, Orfanos SE, Mastora Z, Jahaj E, Paparountas T, Armaganidis A, Roussos C, Aidinis V ,Kotanidou A. 2013, "Induced expression and functional effects of Aquaporin-1 in human leukocytes in sepsis.", Crit Care. , 2013 Sep 12; 17(5):R199. [PubMed]

Nikitopoulou I, Kaffe E, Sevastou I, Sirioti I, Samiotaki M, Madan D, Prestwich GD, Aidinis V. 2013, "A metabolically-stabilized phosphonate analog of lysophosphatidic Acid attenuates collagen-induced arthritis.", PLoS One. , 2013 Jul 29; 8(7) [PubMed], [PDF].

Sevastou I, Kaffe E, Mouratis MA, Aidinis V. 2013, "Lysoglycerophospholipids in chronic inflammatory disorders: The PLA(2)/LPC and ATX/LPA axes.", Biochim Biophys Acta. , 2013 Jan;1831(1):42-60. Epub 2012 Jul 31 [PubMed].

Paparountas T, Nikolaidou-Katsaridou N, Rustici G, Aidinis V. 2012, "Data Mining and Meta-Analysis on DNA Microarray Data.", IJSBBT, 1(3): 1-39 [Article].

Oikonomou N, Mouratis MA, Tzouvelekis A, Kaffe E, Valavanis C, Vilaras G, Karameris A, Prestwich GD, Bouros D, Aidinis V. 2012, "Pulmonary Autotaxin Expression Contributes to the Pathogenesis of Pulmonary Fibrosis.", Am J Respir Cell Mol Biol, 2012 Nov;47(5):566-74. Epub 2012 Jun 28 [PubMed].

Chandras C, Zouberakis M, Salimova E, Smedley D, Rosenthal N, Aidinis V. 2012, "CreZOO--the European virtual repository of Cre and other targeted conditional driver strains.", Database (Oxford), 2012 Jun 21; 2012:bas029. Print 2012. [PubMed].

Nikitopoulou I, Oikonomou N, Karouzakis E, Sevastou I, Nikolaidou-Katsaridou N, Zhao Z, Mersinias V, Armaka M, Xu Y, Masu M, Mills GB, Gay S, Kollias G, Aidinis V. 2012, "Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis.", J Exp Med., 2012 May 7; 209(5):925-33. Epub 2012 Apr 9. [PubMed].

Mouratis MA, Aidinis V. 2011, "Modeling pulmonary fibrosis with bleomycin.", Curr Opin Pulm Med., 2011 Sep; 17(5):355-61. [PubMed].

Schofield PN, Eppig J, Huala E, de Angelis MH, Harvey M, Davidson D, Weaver T, Brown S, Smedley D, Rosenthal N, Schughart K, Aidinis V, Tocchini-Valentini G, Hancock JM. 2010, "Research funding. Sustaining the data and bioresource commons.", Science. , 2010 Oct 29; 330(6004):592-3. [PubMed].

Zouberakis M, Chandras C, Swertz M, Smedley D, Gruenberger M, Bard J, Schughart K, Rosenthal N, Hancock JM, Schofield PN, Kollias G, Aidinis V 2010, "Mouse Resource Browser--a database of mouse databases.", Database (Oxford). , Jul 6 2010, baq010. [PubMed].

Smedley D, Schofield P, Chen CK, Aidinis V., Ainali C, Bard J, Balling R, Birney E, Blake A, Bongcam-Rudloff E, Brookes AJ, Cesareni G, Chandras C, Eppig J, Flicek P, Gkoutos G, Greenaway S, Gruenberger M, Hériché JK, Lyall A, Mallon AM, Muddyman D, Reisinger F, Ringwald M, Rosenthal N, Schughart K, Swertz M, Thorisson GA, Zouberakis M, Hancock JM. 2010, "Finding and sharing: new approaches to registries of databases and services for the biomedical sciences..", Database (Oxford) , Jul 6;2010, baq014 [PubMed].

Chatzigeorgiou A, Harokopos V, Mylona-Karagianni C, Tsouvalas E, Aidinis V, Kamper E. 2010, "The pattern of inflammatory/anti-inflammatory cytokines and chemokines in type 1 diabetic patients over time.", Ann Med. , 2010 Jun 23., 2010 Sep;42(6):426-38 [PubMed].

Xirakia C, Koltsida O, Stavropoulos A, Thanassopoulou A, Aidinis V, Sideras P, Andreakos E. 2010, "TLR7-triggered Immune Response in the Lung Mediates Acute and Long-lasting Suppression of Experimental Asthma.", Am J Respir Crit Care Med. , Jun 1;181(11): , 1207-16 [PubMed].

Fotopoulou S, Oikonomou N, Grigorieva E, Nikitopoulou I, Paparountas T, Thanassopoulou A, Zhao Z, Xu Y, Kontoyiannis DL, Remboutsika E, Aidinis V 2010, "ATX expression and LPA signalling are vital for the development of the nervous system.", Dev Biol., Mar 15;339(2) , :451-64 [PubMed].

Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J, Wood J, EUMODIC Consortium , de Angelis MH, Brown SD, Hancock JM, Mallon AM., 2010, "EuroPhenome: a repository for high-throughput mouse phenotyping data.", Nucleic Acids Res, 2010 Jan;38(Database issue):, D577-85. [PubMed].

Christina Chandras, Thomas Weaver, Michael Zouberakis, Damian Smedley, Klaus Schughart, Nadia Rosenthal, John M. Hancock, George Kollias, Paul N. Schofield, and Aidinis V., 2009, "Models for financial sustainability of biological databases and resources ", Database (2009), Vol. 2009, , bap017; [PubMed].

Kotsianidis I, Nakou E, Bouchliou I, Tzouvelekis A, Spanoudakis E, Steiropoulos P, Sotiriou I, Aidinis V., Margaritis D, Tsatalas C, Bouros D., 2009, "Global Impairment of CD4+CD25+FOXP3+ T Regulatory Cells in Idiopathic Pulmonary Fibrosis.", Am J Respir Crit Care Med., Apr 2, 179(12):1121-30 [PubMed].

Katsanou V, Milatos S, Yiakouvaki A, Sgantzis N, Kotsoni A, Alexiou M, Harokopos V, Aidinis V., Hemberger M, Kontoyiannis DL., 2009, "The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development.", Mol Cell Biol., 29(10) :, 2762-76 [PubMed].

Tzouvelekis A, Aidinis V, Harokopos V, Karameris A, Zacharis G, Mikroulis D, Konstantinou F, Steiropoulos P, Sotiriou I, Froudarakis M, Pneumatikos I, Tringidou R, Bouros D. , 2009, "Down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis.", Respir Res. , Feb 27. 10(1):14.[Epub ahead of print] [Pubmed].

Maniatis NA, Harokopos V, Thanassopoulou A, Oikonomou N, Mersinias V, Witke W, Orfanos SE, Armaganidis A, Roussos C, Kotanidou A, and Aidinis V., 2009, "A Critical Role for Gelsolin in Ventilator-Induced Lung Injury.", Am J Respir Cell Mol Biol. , 41(4): 426-32 [Pubmed].

Oikonomou N, Thanassopoulou A, Tzouvelekis A, Harokopos V, Paparountas T, Nikitopoulou I, Witke W, Karameris A, Kotanidou A, Bouros D, and Aidinis V., 2009, "Gelsolin expression is necessary for the development of modelled pulmonary inflammation and fibrosis.", Thorax. , 64(6): 467-75 [Pubmed].

Smedley D, Swertz MA, Wolstencroft K, Proctor G, Zouberakis M, Bard J, Hancock JM, Schofield P. , 2008, "Solutions for data integration in functional genomics: a critical assessment and case study.", Brief Bioinform. , 9(6): 532-44 [Pubmed].

Maglogiannis .I, Sarimveis H.,Kiranoudis C., Chatziioannou A.A., Oikonomou N. and, Aidinis V., 2008, "Radial Basis Function neural networks classification for the recognition of idiopathic pulmonary fibrosis in microscopic images", IEEE Trans Inf Technol Biomed., 12(1): 42-54. [PubMeb].

Vasilopoulos Y, Gkretsi V, Armaka M, Aidinis V, Kollias G 2007, "Actin cytoskeleton dynamics linked to synovial fibroblast activation as a novel pathogenic principle in TNF-driven arthritis.", Ann Rheum Dis.66 Suppl 3:iii23-8 (Review) [PubMed].

Aidinis V. Chandras C, Manoloukos M, Thanassopoulou A, Kranidioti K, Armaka M, Douni E, Kontoyiannis DL, Zouberakis M, Kollias G; the Mugen NoE consortium., 2008, "MUGEN mouse database; Animal models of human immunological diseases.", Nucleic Acids Res., 36 (Database issue) :D1048-54 [Pubmed]

Tzouvelekis A, Harokopos V, Paparountas T,  Oikonomou N,  Chatziioannou A,  Vilaras G,  Tsiambas E, Karameris A,  Bouros D and Aidinis V., 2007, "Comparative expression profiling in pulmonary fibrosis suggests a role of hypoxia-inducible factor-1alpha in disease pathogenesis", Am J Respir Crit Care Med, 176(11) :1108-19 [Pubmed]

The Mouse Phenotype Database Integration Consortium ( John M. Hancock, Niels C. Adams, Aidinis V., Andrew Blake, Judith A. Blake, Molly Bogue, Steve D. M. Brown, Elissa Chesler, Duncan Davidson, Christopher Duran, Janan T. Eppig, Valerie Gailus-Durner, Hilary Gates, Georgios V. Gkoutos, Simon Greenaway, Martin Hrabe´ De Angelis, Kollias George, Sophie Leblanc, Kirsty Lee, Christoph Lengger, Holger Maier, Ann-Marie Mallon, Hiroshi Masuya, David G. Melvin, Werner Mu ller, Helen Parkinson, Glenn Proctor, Eli Reuveni, Paul Schofield, Aadya Shukla, Cynthia Smith, Tetsuro Toyoda, Laurent Vasseur, Shigeharu Wakana, Alison Walling, Jacqui White, Joe Wood, Michalis Zouberakis) , 2007, "Integration of mouse phenome data resources", Mamm. Genome., 18(3):157-63., [Pubmed]

Oikonomou N., Harokopos V., Zalevsky J., Valavanis C., Kotanidou A., Szymkowski D.E., Kollias G. and, Aidinis V., 2006, "Soluble TNF Mediates the Transition from Pulmonary Inflammation to Fibrosis.", PLoS One, 2006 Dec 27, e108 [PubMed].

Argyropoulos C, Chatziioannou AA., Nikiforidis G., Moustakas A., Kollias G. and , Aidinis V., 2006, "Operational criteria for selecting a cDNA microarray data normalization algorithm", Oncol. Rep., 15:983-996. [PubMed]

Aidinis V. Carninci P., Armaka M., Witke W., Harokopos V., Pavelka N., Koczan D., Argyropoulos C., Thwin M., Möller S., Gopalakrishnakone P., Ricciardi-Castagnoli P., Thiesen H.J., Hayashizaki Y. and Kollias G., , 2005, "Twin expression profiling identifies cytoskeletal rearrangements in synovial fibroblasts as a novel pathophysiological determinant of modeled Rheumatoid Arthritis", PLoS Genetics, (Vol 1(4), e48 [PubMed].

The FANTOM consortium and RIKEN Genome Exploration Research group and Genome Science group., 2005, "The transcriptional landscape of the mammalian genome", Science., Sep 2., 309(5740):1559-63 [PubMed].

Thwin M. M., Douni E., Aidinis V., Kollias G., Kodama K., Sato K., Satish R. L., Mahendran R., Gopalakrishnakone P.
, 2004, "Effect of phospholipase A2 inhibitory peptide on inflammatory arthritis in a TNF transgenic mouse model: a time-course ultrastructural study", Arthritis Res. & Ther., 6 (3), R282-94 [PubMed].

Carninci P., Waki K., Shiraki, Konno H., Shibata K., Itoh M., Aizawa K., Arakawa T., Ishii Y., Sasaki Y., Bono H., Kondo S., Sugahara Y., Saito R., Osato N., Fukuda S., Sato K., Watahiki K., Hirozane-Kishikawa T., Nakamura M., Shibata Y., Yasunishi A., Kikuchi N., Yoshiki A., Kusakabe M., Gustincich S., Beisel K., Pavan W., Aidinis V., Nakagawara A., Held W., Iwata H., Kono T., Nakauchi H., Lyons P., Wells C., Hume D., Fagiolini M., Hensch T., Brinkmeier M., Camper S., Muramatsu M., Okazaki Y., Kawai Y., Hayashizaki Y., 2003, "Targeting a complex transcriptome: The construction of the mouse full-length cDNA encyclopedia", Genome Res., 13, 1273-89 [PubMed].

Aidinis V., Plows D., Haralambous S., Armaka M., Papadopoulos P., Kanaki M. Z., Koczan D., Thiesen H. J., Kollias G., 2003, "Functional analysis of an arthritogenic synovial fibroblast", Arthritis Res. & Ther., 5 (3), 140-157 [PubMed].

Aidinis V., Diaz D. C., Gomez C. A., Bachattaraya D., Spanopoulou E., Sanatagata S. E., 2000, "Definition of minimal domains of interaction within the recombination-activating genes 1 and 2 recombinase complex", J. Immunol., 164 (11), 5826-5832 [PubMed].

Aidinis V., Bonaldi T., Beltrame M., Santagata S., Bianchi M. E., Spanopoulou E., 1999, "The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate Recombination Signal Sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2", Mol. Cell. Biol., 19 (10), 6532-6542 [PubMed].

Santagata S., Aidinis V., Spanopoulou S., 1998, "The effect of Me+ cofactors at the initial stages of V(D)J recombination", J. Biol. Chem., 273 (26), 16325-16331 [PubMed].

Manousakis M., Kistis K. G., Aidinis V., Guialis A., Moutsopoulos H. M., 1995, "Detection of Human-specific anti-La (SSB) antibodies in patients with Rheumatoid Arthritis", J. Autoimm., 8, 959-969 [PubMed].

Aidinis V., Sekeris C. E., Guialis A., 1995, "Two immunologically related polypeptides of 72/74 KD specify a novel 70-110S heterogeneous nuclear RNP", Nucleic. Acids. Res., 23 (14), 2742-2753 [PubMed].

Guialis A., Patrinou-Georgoula M., Aidinis V., Sekeris C. E., Moutsopoulos H. M., 1994, "Anti-5S RNP antibody levels correlate with disease activity in a patient with SLE syndrome", Clin. Exp. Immunol., 95, 385-389 [PubMed].

Manousakis M., Kistis K. G., Liu X., Aidinis V., Guialis A., Moutsopoulos H. M., 1993, "Detection of anti-RO (SSA) antibodies in autoimmune diseases: comparison of five methods", Br. J. Rheum., 32, 449-455 [PubMed].

Aidinis V., Dangli A., Makrinos P., Patrinou-Georgoula M., Sekeris C. E., Guialis A., 1990, "Immunochemical identification of a novel nuclear RNP complex of 70-110S from rat liver", In 'Nuclear structure and function', Ed. I. B. Zbarsky and J. R. Harris, Plenum Press, New York, 265-272.

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