Conference Presentations

Abstracts in International Conferences  (from 2004)

1. Douni E, Sekara E, Kamber M, Kontoyiannis D, Kollias G. (2004). Sensitized ENU mutagenesis screen in animal models of chronic inflammatory diseases. Eumorphia annual meeting. 5-7 October, London.

2. Faggioni R, Babcook J, Douni E, Kang J, Schneider A, Manchulenko K, Rathanaswami P, Kollias G (2004). ABX10131: a fully human anti-human TNF mAb generated using XenoMouse® and XenoMax™ technologies. ICS and ICICR 5th Joint International Meeting, October.

3. Douni E, Makrinou E, Mermelekas G, Giannakas N, Kollias G. (2005). A sensitized ENU mutagenesis screen for genetic modifiers of Rheumatoid Arthritis and Inflammatory Bowel Disease. 19th International Mouse Genome Conference. 4-8 November, Strasbourg, France. Abstract No O-15, p.58.

4. Douni E, Makrinou E, Kollias G. (2005). Genome wide analysis of sensitized ENU mutagenesis screens in animal models for arthritis and IBD, as a tool for drug target discovery. Mutation detection workshop. 31 May-4 June, Santorini.

5. Douni E, Armaka M, Makrinou E, Kollias G. (2006). Functional genetic and genomic analysis of modeled arthritis and osteoclastogenesis. 1rst International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, May28-June2, Crete. Aegean Conference Series vol.22, Abstract No5.

6. Douni E, Armaka M, Makrinou E, and Kollias G. (2006). Functional genetic and genomic analysis of modeled arthritis and other bone diseases. 16th European Congress of Immunology. September 6-9, Paris. Abstract No SC55-770.

7. Beirnaert E, Lauwereys M, De Haard H, Casteels P, Jonckheere H, Spinelli S, Cambillau C, Douni E, Kollias G, Hoogenboom H, Dreier T. (2006). Superior efficacy of a format engineered anti-human TNFa nanobody in a transgenic mouse model (Tg197) of polyarthritis.16th European Congress of Immunology. September 6-9, Paris. Abstract No WD60-339.

8. Kranidioti K, Alexopoulou L, Kranidioti K, Xanthoulea S, Denis M, Kotanidou A, Douni E, Blackshear PJ, Kontoyiannis DL, Kollias G. (2006). Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity. 1rst International MUGEN Conference on animal models for human immunological disease.  September 10-13, Athens. Abstract No 27.

9. Douni E, Makrinou E, Giannakas N, Alexakos G, Kollias G. (2006). A sensitized ENU mutagenesis screen for genetic modifiers of Rheumatoid Arthritis and Inflammatory Bowel Disease. 1rst International MUGEN Conference on animal models for human immunological disease.  September 10-13, Athens. Abstract No 44.

10. Sotsios Y, Douni E, Kollias G. (2006). TNF-driven animal models of inflammatory disease: effective tools for pre-clinical in vivo evaluation of pharmaceuticals. 1rst International MUGEN Conference on animal models for human immunological disease.  September 10-13, Athens. Abstract No 52.

11. Douni E, Makrinou E, Kollias G. (2007). Identification of a novel loss-of-function missense mutation in the RANKL gene using ENU mutagenesis. 21rst International Mouse Genome Conference, 28 October-1 November, Kyoto Japan. Abstract No P108 p.144.

12. Douni E, Makrinou E, Mermelekas G, Giannakas N, Kollias G. (2007). Identification of genetic modifiers using random mutagenesis in Rheumatoid Arthritis and Inflammatory Bowel Disease. 21rst International Mouse Genome Conference, 28 October-1 November, Kyoto Japan. Abstract No P109 p.144.

13. Douni E, Makrinou E, Kollias G. (2008). Identification of a novel loss-of-function missense mutation in the RANKL gene that causes osteopetrosis in mice. 35th European Symposium on calcified tissues. 24-28 May, Barcelona Spain. Published in Calcified Tissue International vol 82, suppl. Abstract Mo-OP35 p.S57.

14. Douni E, Makrinou E, Zwerina J, Penninger JM, Schett G Kollias G. (2008). Identification and characterization of a novel loss-of-function missense mutation in the RANKL gene that causes osteopetrosis in mice. 2nd International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, June 8-13, Rhodes. Aegean Conference Series vol.35, Abstract No 62.

15. Douni E, Aidinis V, Kontoyiannis D, Graf D, Kollias G. (2009). Secondary immunological phenotyping using animal models for human inflammatory and autoimmune diseases: the MUGEN approach. EUMODIC Annual Meeting, March 2-4, Athens, Greece.

16. Niti A, Rinotas V, Douni E. (2009). A novel humanized RANKL transgenic mouse model of osteoporosis. 36th European Symposium on calcified tissues, 23-27 May, Vienna. Bone vol44, no2 p.S423.

17. Ioakeimidis F, Rinotas V, Makrinou E, Kollias G, Douni E. (2009). Characterization of a novel mouse model of autosomal recessive neuromuscular disease and lymphoid hypoplasia generated by ENU mutagenesis [MUGEN fellowship]. 4th ENII-MUGEN Immunology Summer School, 17-24 May, Capo Caccia, Sardinia.

18. Niti A, Rinotas V, Douni E. (2009). A novel genetic model of osteoporosis in transgenic mice expressing human RANKL. 2nd MUGEN Conference, 8-10 October, Athens.

19. Ioakeimidis F, Karakostas A, Rinotas V, Makrinou E, Kollias G, Douni E. (2009). A novel ENU-induced mouse model of autosomal recessive neuromuscular disease and lymphoid abnormalities. 2nd MUGEN Conference, 8-10 October, Athens.

20. Karakostas A, Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2009). Identification of a new SLC25 member that causes autosomal recessive ataxia in ENU-mutagenized mice. 2nd MUGEN Conference, 8-10 October, Athens.

21. Douni E, Aidinis V, Kontoyiannis D, Graf D, Kollias G. (2010). Secondary immunological phenotyping using animal models for human inflammatory and autoimmune diseases. EUMODIC Annual Meeting, March 25-26, Brussels.

22. Karakostas A, Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2010). Identification and characterization of a novel SLC25 member that causes autosomal recessive ataxia in mice. EUMODIC Annual Meeting, March 25-26, Brussels.

23. Niti A, Dacquin R, Rinotas V, Jurdic P, Douni E. (2010). Generation and analysis of a novel genetic model of osteoporosis:Human RANKL-expressing transgenic mice. 3rd International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, June 20-25, Santorini. Aegean Conference Series vol.49, Abstract No 65.

24. Ioakeimidis F, Rinotas V, Makrinou E, Kollias G, and Douni E. (2010).Identification of a novel member of the DnaJC family that causes neuromuscular disease in mice. Neuroscience days of the Hellenic Society for Neuroscience. 1-2 October, Athens.

25. Karakostas A, Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2010). Identification of a novel SLC25 member that causes autosomal recessive ataxia in ENU-mutagenized mice. Neuroscience days of the Hellenic Society for Neuroscience. 1-2 October, Athens.

26. Ioakeimidis F, Rinotas V, Makrinou E, Kollias G, Douni E. (2010). A forward genetics approach identifies a novel member of the DnaJC family that causes neuromuscular disease in mice. 24th International Mammalian Genome Conference. 17-21 October, Heraklion.

27. Karakostas A, Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2010). Identification of a novel SLC25 member that causes autosomal recessive ataxia in ENU-mutagenized mice. 24th International Mammalian Genome Conference. 17-21 October, Heraklion.

28. Niti A, Dacquin R, Rinotas V, Jurdic P, Douni E. (2010). A novel genetic model of osteoporosis by overexpression of human RANKL in transgenic mice. 24th International Mammalian Genome Conference. 17-21 October, Heraklion.

29. Niti A, Dacquin R, Bonnet N, Rinotas V, Ferrari S, Jurdic P, Douni E. (2011). Novel genetic models of osteoporosis by overexpressing human RANKL in transgenic mice. 38th European Symposium on calcified tissues, 7-11 May, Athens.

30. Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2011). A novel member of the DNAJC family localized in mitochondria causes neuromuscular disease and immune abnormalities in mice. Mitochondria dynamics: from mechanisms to disease.11-15 September, Sardinia.

31. Niti A, Dacquin R, Bonnet N, Rinotas V, Ferrari S, Jurdic P and Douni E. (2011). Novel genetic models of osteoporosis in transgenic mice overexpressing human RANKL. Final EUMODIC meeting, 21-22 November, Geneva.

32. Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2011). A novel member of the DNAJC family causes neuromuscular disease and immune abnormalities in mice. Final EUMODIC meeting, 21-22 November, Geneva.

33. Ioakeimidis F, Rinotas V, Fasseas C,  Kollias G and Douni E. (2012). An ENU Forward Genetics Approach in Mice Identifies a Role of a Novel Mitochondrial DnaJC Protein in Mitochondrial Structure and Proper Neuromuscular Function. Mitochondria in life, death and disease, FEBS/EMBO course, 9-13 May, Crete Greece. [Selected oral presentation].

34. Kano T, Karakostas A, Ioakeimidis F, Rinotas V, Kollias G, and Douni E.  (2012). A Novel SLC25 Member of Mitochondrial Carriers Causes Autosomal Recessive Neurological Disease in Mice. Mitochondria in life, death and disease, FEBS/EMBO course, 9-13 May, Crete Greece.

35. Niti A, Dacquin R, Bonnet N, Rinotas V, Ferrari S, Jurdic P and Douni E. (2012). Modeling osteoporosis in transgenic mice overexpressing human RANKL. 4th  International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, June 18-21, Corfu Greece.

36. Rinotas V, Alexiou P, Papakyriakou T, Papaneophytou C, Kontopidis G, Couladouros E,  Eliopoulos E, and Douni E. (2012). Development of novel therapeutic approaches targeting RANKL trimerization. 4th International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, June 18-21, Corfu Greece.

37. Rinotas V, Dacquin R, Bonnet N, Ferrari S, Jurdic P, Alexiou P, Papakyriakou T, Papaneophytou C, Kontopidis G, Couladouros E, Eliopoulos E, Douni E. 2012. Study of RANKL-mediated pathogenic mechanisms in mouse models and development of new therapeutic approaches. 5th International Workshop on Advances in the Molecular Pharmacology and Therapeutics of Bone Disease, 27-30 June Oxford, UK.

38. Violitzi F, Rinotas V, Douni E. (2012). Inhibition of BAFF trimerization with site-directed mutagenesis. 2nd Conference on Agricultural Biotechnology, 4-5 October, Athens.

39. Terzenidou M, Kano T, Karakostas A, Ioakeimidis F, Kollias G, Douni E. (2012). Studying the pathogenic role of a novel SLC25 mitochondrial carrier in a genetic mouse model of neurological disease. 2nd Conference on Agricultural Biotechnology, 4-5 October, Athens.

40.  Rinotas V, Niti A, Kontopidis G, Couladouros E, Eliopoulos E, Douni E. (2012). Study of RANKL-mediated pathogenic mechanisms in mouse models and development of new therapeutic approaches. 2nd Conference on Agricultural Biotechnology, 4-5 October, Athens.

41.  Ioakeimidis F, Rinotas V, Fasseas C, Kollias G, Douni E. (2012). Identification of the role of DNAJC in mitochondrial structure and neuromuscular function in mice. 2nd Conference on Agricultural Biotechnology, 4-5 October Athens.

42. Ioakeimidis F, Rinotas V, Fasseas C, Kollias G, Douni E. (2012).  DnaJC11 is involved in mitochondrial cristae structure and neuromuscular disease in mice. Neuroscience Days, 2-3 November, Athens.

43. Terzenidou M, Kano T, Karakostas A, Ioakeimidis F, Kollias G, Douni E. (2012). A nonsense mutation in a novel SLC25 family gene of mitochondrial carriers causes severe recessive neurological disease in mice. Neuroscience Days, 2-3 November, Athens.

44. Rinotas V, Violitzi F, Alexiou P, Liepouri F, Maranti A, Tsiliouka K, Strongilos A, Papakyriakou T, Papaneophytou C, Kontopidis G, Couladouros E,  Eliopoulos E, Douni E. (2013). Novel SPD304-like inhibitors targeting trimerization of human RANKL.  5th International BBBB Conference “From Drug Discovery and Formulation Strategies to Pharmacokinetics-Pharmacodynamics”, 26-28 September, Athens.

45. Rinotas V, Niti A, Dacquin R, Bonnet N, Ferrari S, Jurdic P, Douni E. (2013). Novel models of osteoporosis in transgenic mice overexpressing human RANKL. ASBMR Annual Meeting, 4-7 October, Baltimore, USA.

46. Rinotas V, Violitzi F, Alexiou P, Liepouri F, Maranti A, Tsiliouka K, Strongilos A, Papakyriakou T, Papaneophytou C, Kontopidis G, Couladouros E,  Eliopoulos E, Douni E. (2013) Novel human RANKL inhibitors targeting its trimerization.  ASBMR Annual Meeting, 4-7 October, Baltimore, USA.

47. Terzenidou M, Kano T, Karakostas A, Ioakeimidis F, Kollias G, Douni E. (2013). Identification of a novel SLC25 family member of mitochondrial carriers causing recessive neurological disease in mice. 64th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 6-8 December 2013.

48. Rinotas V, Papadaki M, Dacquin R, Bonnet N, Jurdic P, Ferrari S, Douni E. (2013). Novel osteoporosis models by overexpressing human RANKL in transgenic mice. 64th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 6-8 December 2013.

49. Terzenidou M, Kano T, Karakostas A, Ioakeimidis F, Kollias G, Douni E. (2013). A novel SLC25 family member of mitochondrial carriers causes severe recessive neurological disease in mice. 64th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 6-8 December 2013.

50. Rinotas V, Violitzi F, Alexiou P, Liepouri F, Maranti A, Tsiliouka K, Strongilos A, Papakyriakou T, Papaneophytou C, Kontopidis G, Couladouros E,  Eliopoulos E, Douni E. (2013). Novel SPD304-like inhibitors targeting trimerization of human RANKL.  5th International BBBB Conference “From Drug Discovery and Formulation Strategies to Pharmacokinetics-Pharmacodynamics”, 26-28 September, Athens.

51. Rinotas V, Niti A, Dacquin R, Bonnet N, Ferrari S, Jurdic P, Douni E. (2013). Novel models of osteoporosis in transgenic mice overexpressing human RANKL. ASBMR Annual Meeting, 4-7 October, Baltimore, USA.

52. Rinotas V, Violitzi F, Alexiou P, Liepouri F, Maranti A, Tsiliouka K, Strongilos A, Papakyriakou T, Papaneophytou C, Kontopidis G, Couladouros E,  Eliopoulos E, Douni E. (2013). Novel human RANKL inhibitors targeting its trimerization.  ASBMR Annual Meeting, 4-7 October, Baltimore, USA.

53.Terzenidou M, Kano T, Karakostas A, Ioakeimidis F, Kollias G, Douni E. (2013). Identification of a novel SLC25 family member of mitochondrial carriers causing recessive neurological disease in mice. 64th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 6-8 December 2013. 

54. Rinotas V, Papadaki M, Dacquin R, Bonnet N, Jurdic P, Ferrari S, Douni E. (2013). Novel osteoporosis models by overexpressing human RANKL in transgenic mice. 64th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 6-8 December 2013.

55. Terzenidou M, Kano T, Karakostas A, Ioakeimidis F, Kollias G, Douni E. (2013). A novel SLC25 family member of mitochondrial carriers causes severe recessive neurological disease in mice. 64th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 6-8 December 2013.

56.Rinotas V, Niti A, Dacquin R, Bonnet N, Ferrari S, Jurdic P, Douni E. (2014). Novel models of osteoporosis in transgenic mice overexpressing human RANKL. World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal diseases, 2-5 April, Seville, Spain. 

57.Rinotas V, Violitzi F, Alexiou P, Liepouri F, Maranti A, Tsiliouka K, Strongilos A, Papakyriakou T, Papaneophytou C, Kontopidis G, Couladouros E,  Eliopoulos E, Douni E.  (2014) Novel small molecule inhibitors of human RANKL that targe its trimerization. 5th International Conference on Osteoimmunology: Interactions of the Immune and Skeletal Systems, 15-19 June, Kos, Greece. 

58.Papadaki M, Rinotas V, Douni E. (2014). Osteoimmunological analysis in transgenic mice overexpressing human RANKL. 5th International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, June 15-20, Kos, Greece. 

59.Ioakeimidis F, Violitzi F, Ott C, Kozjak-Pavlovic V, Rinotas V, Fasseas C, Douni E. (2014). A splicing mutation in the novel mitochondrial HSP40 co-chaperone DNAJC11 causes neuromuscular disease and lymphoid abnormalities in mice. 65th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 28-30 November, Thessaloniki, Greece. 

60.Terzenidou M, Segklia A, Kano T, Karakostas A, Violitzi V, Ioakeimidis F, Matsas R, Kollias, Douni. E. (2014). A nonsense point mutation in a novelSLC25 family member of mitochondrialcarrierscauses severe recessive neurological disease and cerebellar pathology in mice. 65th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 28-30 November, Thessaloniki, Greece. 

61.Papadaki  M, Rinotas V, Kollias G, Douni E. (2014). Osteoimmunological interactions in transgenic mice overexpressing human RANKL. 65th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 28-30 November, Thessaloniki, Greece. 

62.Violitzi F, Samiotaki M, Ioakeimidis F, Boyongo M, Panayotou G, Douni E. (2014). Understanding the physiological role of DNAJC11 through identification of its interactors. 65th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 28-30 November, Thessaloniki, Greece. 

63. Kano Τ, Rokidi S, Remboutsika E, Mouzakis D, Zaoutsos S, Bouropoulos N, Douni E. (2015). Mechanical stress analysis and osteoblastic induction on calcium phosphate-hydroxyapatite cements. 4th Joint Meeting of the ECTS and IBMS, 25-28 April, Rotterdam, The Netherlands.

64. Papadaki M, Rinotas V, Kollias G, Douni E. (2015). Analysis of Osteoimmune Interactions in Transgenic Mice Overexpressing Human RANKL. 4th Joint Meeting of the ECTS and IBMS, 25-28 April 2015, Rotterdam, The Netherlands.

65. Rinotas V, Chalkidi N, Violitzi Fi, Alexiou P, Liepouri F, Maranti A, Tsiliouka K, Strongilos A, Papakyriakou T, Papaneophytou C, Kontopidis G, Couladouros E, Eliopoulos E, Douni E. (2015). Novel small molecule inhibitors of human RANKL. 4th Joint Meeting of the ECTS and IBMS, 25-28 April, Rotterdam, The Netherlands.

66. Kano Τ, Rokidi S, Remboutsika E, Mouzakis D, Zaoutsos S, Bouropoulos N, Douni E. (2015). Phosphate-Hydroxyapatite Cements: Mechanical Stress Analysis and Osteoblastic Induction. 27th European Conference on Biomaterials, 30 August - 3 September, Krakow, Poland.

67. Terzenidou M, Segklia A, Kano T, Karakostas A, Violitzi V, Ioakeimidis F, Kollias G, Matsas R, Douni E. (2015). A nonsense point mutation in a novelSLC25 family member of mitochondrialcarriers causes severe recessive neurological pathology in mice. FEBS/EMBO Course: Mitochondria in Life, Disease and Death, 12-15 October, Heraklion, Crete, Greece.

68. Violitzi F, Samiotaki M, Ioakeimidis F, Panayotou G, Douni E. (2015). Investigating the function of the novel mitochondrial HSP40 co-chaperone DNAJC11 through domain characterization and identification of its interactors. FEBS/EMBO Course: Mitochondria in Life, Disease and Death, 12-15 October, Heraklion, Crete, Greece.

69. Ioakeimidis F, Violitzi F, Rinotas V, Gialitaki E, Ott C, Kozjak-Pavlovic V, Fasseas C, Douni E. (2015). A splicing mutation in the novel mitochondrial HSP40 co-chaperone DNAJC11 causes motor neuron pathology and cristae disorganization mice. FEBS/EMBO Course: Mitochondria in Life, Disease and Death, 12-15 October, Heraklion, Crete, Greece.

70. Charalambous M, Papastefanaki F, Terzenidou M, Douni E, Matsas R. (2015). The pathophysiological role of a novel SLC25 family member in the spinal cord and sciatic nerve of mutant mice. 66th Congress of the Hellenic Society of Biochemistry and Molecular Biology , 11-13 December,  Athens, Greece. 

71. Terzenidou M, Segklia A, Kano T, Karakostas A, Violitzi V, Ioakeimidis F, Kollias G, Matsas R,  Douni E. (2015). Identification of a novel SLC25 family member causing severe recessive neurological pathology in mice.  66th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 11-13 December, Athens, Greece. 

72. Rinotas V, Violitzi F, Alexiou P, Liepouri F, Maranti A, Tsiliouka K, Strongilos A, Papakyriakou T, Papaneophytou C, Kontopidis G, Couladouros E,  Eliopoulos E, Douni E. (2015). Identification of small molecule inhibitors of RANKL as novel antiresorptive agents in osteoporosis. 66th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 11-13 December, Athens, Greece. 

73. Papadaki  M, Rinotas V, Plestilova L, Kollias G, Jüngel A, Douni E. (2015). Expression profile and osteoimmunological interactions in osteoporotic transgenic mice overexpressing human RANKL. 66th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 11-13 December, Athens, Greece. 

74. Violitzi F, Samiotaki M, Ioakeimidis F, Rinotas V, Panayotou G, Douni E. (2015). Domain characterization and identification of  protein interactors of the novel mitochondrial DNAJC11 protein that causes a neuromuscular phenotype in mice. 66th Congress of the Hellenic Society of Biochemistry and Molecular Biology, 11-13 December, Athens, Greece. 

75. Papadaki  M, Rinotas V, Plestilova L, Kollias G, Jüngel A, Douni E. (2016). Osteoimmunological interactions and expression profile in osteoporotic transgenic mice overexpressing human RANKL. 6th International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, June 17-22, Chania, Greece. 

76. Rinotas V, Papadaki M, Douni E. (2016). Bone marrow adipogenesis in  transgenic mice expressing human RANKL. 6th International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, June 17-22, Chania, Greece. 

77. Rinotas V, Siniorakis E, Papadaki M, Douni E. (2016). Analysis of bone marrow adiposity in human RANKL-expressing transgenic mouse models of osteoporosis. 2nd Bone Marrow Adiposity Meeting, 25-26 August, Rotterdam, The Netherlands.

 

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