Panagiotis Moulos Research Group

• Bothos, E., Hatzis, P., Moulos, P.: Interactive Analysis, Exploration, and Visualization of RNA-Seq Data with SeqCVIBE, Methods Protoc, 2022, 5(2):27.
• Galaris, A., Fanidis, D., Stylianaki, E.A., Harokopos, V., Kalantzi, A.S., Moulos, P., Dimas, A.S., Hatzis, P., Aidinis, V.: Obesity Reshapes the Microbial Population Structure along the Gut-Liver-Lung Axis in Mice, Biomedicines, 2022, 10(2):494.
• Kiparaki, M., Khan, C., Folgado-Marco, V., Chuen, J., Moulos, P., Baker NE.: The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function, eLife, 2022, 11:e71705.
• Röling, M., Mollapour, S.M., Ne, E., Moulos, P., Crespo, R., Stoszko, M., De Crignis, E., Bodmer, H., Kan, T.W., Akbarzadeh, M., Harokopos, V., Hatzis, P., Palstra, R.J., Mahmoudi, T.: A Two-Color Haploid Genetic Screen Identifies Novel Host Factors Involved in HIV-1 Latency, mBio. 2021, 12(6):e0298021.
• Fanidis, D., Moulos, P., Aidinis, V.: Fibromine is a multi-omics database and mining tool for target discovery in pulmonary fibrosis, Sci Rep. 2021, 11(1):21712.
• Dimopoulos, A., Koukoutegos, K., Psomopoulos, E.F., Moulos, P.: Combining multiple RNA-Seq data analysis algorithms using Machine Learning improves differential isoform expression analysis, Methods Protoc. 2021, 4(4):68.
• Sfikakis, P., Verrou, K.M., Ampatziadis-Michailidis, G., Tsitsilonis, O., Paraskevis, D., Kastritis, E., Lianidou, E., Moutsatsou, P., Terpos, E., Trougakos, E., Chini, V., Manoloukos, M., Moulos, P., Pavlopoulos, GA., Kollias, G., Hatzis, P., Dimopoulos, M.A.: Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection, Front Immunol. 2021, 12:746203.
• Nikitopoulou, I., Fanidis, D., Ntatsoulis, K., Moulos, P., Mpekoulis, G., Evangelidou, M., Vassiliou, A.G., Dimakopoulou, V., Jahaj, E., Tsipilis, S., Orfanos, S.E., Dimopoulou, I., Angelakis, E., Akinosoglou, K., Vassilaki, N., Tzouvelekis, A., Kotanidou, A., Aidinis, V.: Increased Autotaxin Levels in Severe COVID-19, Correlating with IL-6 Levels, Endothelial Dysfunction Biomarkers, and Impaired Functions of Dendritic Cells, International Journal of Molecular Sciences 2021, 22(18):10006.
• De Crignis, E., Hossain, T., Romal, S., Carofiglio, F., Moulos, P., Khalid, M.M., Rao, S., Bazrafshan, A., Verstegen, M.M., Pourfarzad, F., Koutsothanassis, C., Gehart, H., Kan, T.W., Palstra, R.J., Boucher, C., IJzermans, J.N., Huch, M., Boj, S.F., Vries, R., Clevers, H., van der Laan, L.J., Hatzis, P., Mahmoudi, T.: Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma, eLife 2021, 10:e60747.
• Kostaki, G.E., Pavlopoulos, G.A., Verrou, K.M., Ampatziadis-Michailidis, G., Harokopos, V., Hatzis, P., Moulos, P., Siafakas, N., Pournaras, S., Hadjichristodoulou, C., Chatzopoulou, F., Chatzidimitriou, C., Panagopoulos, P., Lourida, P., Argyraki, A., Lytras, T., Sapounas, S., Gerolymatos, G., Panagiotakopoulos, G., Prezerakos, P., Tsiodras, S., Sypsa, V., Hatzakis, A., Anastassopoulou, C., Spanakis, N., Tsakris, A., Dimopoulos, M.A., Kotanidou, A., Sfikakis, P., Kollias, G., Magiorkinis, G., Paraskevis, D.: Molecular epidemiology of SARS-CoV-2 in Greece reveals low rates of onward virus transmission after lifting of travel restrictions based on risk assessment during summer 2020, mSphere 2021, 6(3):e0018021.
• Bothos, E., Ntoumou, E., Kelaidoni, K., Roukas, D., Drakoulis, N., Papasavva, M., Karakostis, F.A., Moulos, P., Karakostis, K.: Clinical pharmacogenomics in action: design, assessment and implementation of a novel pharmacogenetic panel supporting drug selection for diseases of the central nervous system (CNS), J Transl Med. 2021, 19(1):151.
• Verrou, K.M., Vlachogiannis, N.I., Ampatziadis-Michailidis, G., Moulos, P., Pavlopoulos, G.A., Hatzis, P., Kollias, G., Sfikakis, P.P.: Distinct transcriptional profile of blood mononuclear cells in Behcet's disease: insights into the central role of neutrophil chemotaxis, Rheumatology 2021, keab052.
Moulos, P.: recoup: versatile signal visualization from genomic sequencing, BMC Bioinformatics 2021, 22(1):2.
• Fanidis, D., Moulos, P.: Integrative, normalization-insusceptible statistical analysis of RNA-Seq data, with improved differential expression and unbiased downstream functional analysis, Briefings in Bioinformatics 2020, bbaa156.
• Gioulbasani, M., Galaras, A., Grammmenoudi, S., Moulos, P., Dent, A., Sigvardsson, M., Hatzis, P., Kee, B.L., Verykokakis, M.: The transcription factor BCL6 controls early development of innate-like T cells, Nature Immunology 2020, 21(9), 1058-1069.
• Buffin-Meyer, B., Klein, J., van der Zanden, L.F.M., Levtchenko, E., Moulos, P., Lounis, N., Conte-Auriol, F., Hindryckx, A., Wühl, E., Persico, N., Oepkes, D., Schreuder, M.F., Tkaczyk, M., Ariceta, G., Fossum, M., Parvex, P., Feitz, W., Olsen, H., Montini, G., Decramer, S., Schanstra, J.P.; ANTENATAL Consortium: The ANTENATAL multicentre study to predict postnatal renal outcome in fetuses with posterior urethral valves: objectives and design, Clin Kidney J. 2019, 13(3):371-379.
• Karagianni, P., Moulos, P., Odom, D., Talianidis, I: Bookmarking by non-pioneer transcription factors during liver development establishes competence for future gene activation. Cell Rep. 2020, 30(5):1319-1328.e61.
Moulos, P., Alexandratos, A., Nellas, I., Dedos, S.G.: Refining a steroidogenic model: an analysis of RNA-seq datasets from insect prothoracic glands. BMC Genomics 2018, 19(1):537.
• Buffin-Meyer, B., Klein, J., Breuil, B., Muller, F., Moulos, P., Groussolles, M., Bouali, O., Bascands, J.-L., Decramer, S., Schanstra, J.-P.: Combination of the fetal urinary metabolome and peptidome for the prediction of postnatal renal outcome in fetuses with PUV. J Proteomics 2018, 184:1-9.
• Nikolaou, K.C., Moulos, P., Harokopos, V., Chalepakis, G., Talianidis, I.: Kmt5a Controls Hepatic Metabolic Pathways by Facilitating RNA Pol II Release from Promoter-Proximal Regions. Cell Rep. 2017, 20(4):909-922.
• Apostolou, G., Apostolou, N., Moulos, P., Chatzipantelis, P.: Endometrial cytopathology. An image analysis approach using the Ki-67 biomarker. Cytopathology 2017, 28(5):385-390.
• Papadopoulos, T., Casemayou, A., Neau, E., Breuil, B., Caubet, C., Calise, D., Thornhill, B.A., Bachvarova, M., Belliere, J., Chevalier, R.L., Moulos, P., Bachvarov, D., Buffin-Meyer, B., Decramer, S., Auriol, F.C., Bascands, J.L., Schanstra, J.P., Klein, J.: Systems biology combining human- and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction. BMC Syst Biol. 2017, 11(1):31.
• Boizard, F., Brunchault, V., Moulos, P., Breuil, B., Klein, J., Lounis, N., Caubet, C., Tellier, S., Bascands, J.L., Decramer, S., Schanstra, J.P., Buffin-Meyer, B.: A capillary electrophoresis coupled to mass spectrometry pipeline for long term comparable assessment of the urinary metabolome. Sci Rep. 2016, 6:34453.
Moulos, P., Samiotaki, M., Panayotou, G., Dedos, S.G.: Combinatory annotation of cell membrane receptors and signalling pathways of Bombyx mori prothoracic glands. Sci Data. 2016, 3:160073.
• Giakountis, A., Moulos, P., Sarris, M.E., Hatzis, P., Talianidis, I.: Smyd3-associated regulatory pathways in cancer. Semin Cancer Biol. 2016, S1044-579X(16)30041-4.
• Papadodima, O., Moulos, P., Koryllou, A., Piroti, G., Kolisis, F., Chatziioannou, A., Pletsa, V.: Modulation of Pathways Underlying Distinct Cell Death Mechanisms in Two Human Lung Cancer Cell Lines in Response to SN1 Methylating Agents Treatment. PLoS One. 2016, 11(7):e0160248.
• Giakountis, A, Moulos, P., Zarkou, V., Oikonomou, C., Harokopos, V., Hatzigeorgiou, A.G., Reczko, M., Hatzis, P.: A Positive Regulatory Loop between a Wnt-Regulated Non-coding RNA and ASCL2 Controls Intestinal Stem Cell Fate. Cell Reports. 2016, S2211-1247(16)30621-0.
Moulos, P., Sarris, M.E., Talianidis, I.: Mechanism of gene-specificity of oncogenic regulators. Cell Cycle. 2016 May 31:0. [Epub ahead of print]
• Arvaniti, E., Moulos, P., Vakrakou, A., Chatziantoniou, C., Chadjichristos, C., Kavvadas, P, Charonis, A., Politis, P.K.: Whole-transcriptome analysis of UUO mouse model of renal fibrosis reveals new molecular players in kidney diseases. Sci Rep. 2016, 6:26235.
• Sarris, M.E., Moulos, P., Haroniti, A., Giakountis, A., Talianidis, I.: Smyd3 Is a Transcriptional Potentiator of Multiple Cancer-Promoting Genes and Required for Liver and Colon Cancer Development. Cancer Cell. 2016, 29(3):354-66.
• Alexandratos, A., Moulos, P., Nellas, I., Mavridis, K., Dedos. S.G.: Reassessing ecdysteroidogenic cells from the cell membrane receptors' perspective. Sci Rep. 2016, 6:2022.
• Milongo, D., Bascands, J.-L., Huart, A., Esposito, L., Breuil, B., Moulos, P., Siwy, J., Ramírez-Torres, A., Ribes, D., Lavayssière, L., Del Bello, A., Muscari, F., Alric, L., Bureau, C., Rostaing, L., Schanstra, J.-P., Kamar, N.: Pretransplant urinary proteome analysis does not predict development of chronic kidney disease after liver transplantation. Liver Int. 2015, 35(7), 1893-901.
• Nikolaou, K.C., Moulos, P., Chalepakis, G., Hatzis, P., Oda, H., Reinberg, D., Talianidis, I.: Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers. EMBO J. 2015, 34(4), 430-47.
Moulos, P., Hatzis, P.: Systematic integration of RNA-Seq statistical algorithms for accurate detection of differential gene expression patterns. Nucleic Acids Res. 2015, 43(4), e25.
Moulos, P., Klein,. J., Jupp, S., Stevens, R., Bascands, J.-L., Schanstra, J.P.: The KUPNetViz: A biological network viewer for multiple -omics datasets in kidney diseases. BMC Bioinformatics 2013, 14:235.
• Klein, J., Jupp, S., Moulos, P., Fernandez, M., Buffin-Meyer, B., Chayaa, R., Charonis, A., Bascands, J.-L., Stevens, R., Schanstra, J.-P.: The KUPKB: a novel Web application to access multiomics data on kidney disease. FASEB J. 2012, 26(5), 2145-2153.
• Rao, N.A.S., McCalman, M.T., Moulos, P., Francoijs, K.J., Chatziioannou, A., Kolisis, F.N., Alexis, M.N., Stunnenberg, H.G., Mitsiou, D.J.: Coactivation of GR and NFKB alters the repertoire of their binding sites and target genes. Genome Res. 2011, 21(9), 1404-1416 .
• Chatziioannou, A., Kanaris, I., Doukas, C., Moulos, P., Maglogiannis, I., Kolisis, F.N.: The GRISSOM Platform: Enabling distributed Processing and Management of Biological Data through fusion of Grid and Web Technologies. IEEE Transactions on Information Technology in Biomedicine 2011, 15(1), 83-92.
• Chatziioannou, A., Moulos, P.: Exploiting statistical methodologies and controlled vocabularies for prioritized functional analysis of genomic experiments: The StRAnGER web application. Front Neurosci. 2011, Jan 26, 5:8.
Moulos, P., Papadodima, O., Chatziioannou, A., Loutrari, H., Roussos, C., Kolisis, F.N.: A transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas reveals molecular mechanisms targeting tumor cell growth and survival. BMC Medical Genomics 2009, 2:68.
• Chatziioannou, A., Moulos, P., Kolisis, F.N.: Gene ARMADA: an integrated multi-analysis platform for microarray data implemented in MATLAB. BMC Bioinformatics 2009 10:354.
• Nielsen, R., Pedersen, T.A., Hagenbeek, D., Moulos, P., Siersbaek, R., Megens, E., Denissov, S., Borgesen, M., Francoijs, K.J., Mandrup, S., Stunnenberg, H.G.: Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes Dev 2008, 22(21):2953-2967.