2004 - (22)

Panagopoulos D, Victoratos P, Alexiou M, Kollias G, Mosialos G. 2004 "Comparative analysis of signal transduction by CD40 and the Epstein-Barr virus oncoprotein LMP1 in vivo". J Virol. 2004 Dec;78(23):13253-61. PubMed

Auwerx J., Avner P., Baldock R., Ballabio A., Balling R., Barbacid M., Berns A., Bradley A., Brown S., Carmeliet P., Chambon P., Cox R., Davidson D., Davies K., Duboule D., Forejt J., Granucci F., Hastie N., de Angelis M. H., Jackson I., Kioussis D., Kollias G., Lathrop M., Lendahl U., Malumbres M., von Melchner H., Muller W., Partanen J., Ricciardi-Castagnoli P., Rigby P., Rosen B., Rosenthal N., Skarnes B., Stewart AF, Thornton J., Tocchini-Valentini G., Wagner E., Wahli W., Wurst W., 2004, "The European dimension for the mouse genome mutagenesis program", Nat. Genetics, 36, 925-7 . PubMed

Xanthoulea S., Pasparakis M., Kousteni S., Brakebusch C., Wallach D., Bauer J., Lassmann H., Kollias G., 2004,  "Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases", J. Exp. Med., 2;200 (3), 367-76 . PubMed

Kollias G., 2004, "Modeling the function of tumor necrosis factor in immune pathophysiology", Autoimmun. Rev., 3 Suppl 1, S24-5 . PubMed

Herrak P., Gortz B., Hayer S., Redlich K., Reiter E., Gasser J., Bergmeister H., Kollias G., Smolen J. S., Schett G., 2004, "Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis", Arthritis Rheum., 50 (7), 2327-37. PubMed 

Jono H., Lim J. H., Chen L. F., Xu H., Trompouki E., Pan Z. K., Mosialos G., Li J. D., 2004, "NF-κB Is Essential for Induction of CYLD, the Negative Regulator of NF-κB: Evidence for A Novel Inducible Auto-Regulatory Feedback Pathway", J. Biol. Chem., 279, 36171-36174 . PubMed

Smolen J. S., Hayer S., Schett G., Redlich K., Aringer M., Kollias G., Wagner E., Steiner G., 2004, "Autoimmunity and rheumatoid arthritis", Autoimmun. Rev., 3 Suppl 1, S23 . PubMed

Thwin M. M., Douni E., Aidinis V., Kollias G., Kodama K., Sato K., Satish R. L., Mahendran R., Gopalakrishnakone P., 2004, "Effect of phospholipase A2 inhibitory peptide on inflammatory arthritis in a TNF transgenic mouse model: a time-course ultrastructural study", Arthritis Res. & Ther., 6 (3), R282-94 . PubMed

Staelens J., Puimege L., Mahieu T., Pynaert G., Hochepied T., Vandenabeele A., Grooten J., Kontoyiannis D., Van Roy F., Kollias G., Libert C., 2004, "Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders", Mamm. Genome., 15, 537-543 . PubMed

Kollias G., 2004, "TNF pathophysiology in murine models of chronic inflammation and autoimmunity", Semin Arthritis Rheum., 2005 Apr;34(5 Suppl1), 3-6. Review. PubMed

Redlich K., Gortz B., Hayer S., Zwerina J., Kollias G., Steiner G., Smolen J. S., Schett G., 2004,  "Overexpression of tumor necrosis factor causes bilateral sacroiliitis", Arthritis Rheum., 50 (3), 1001-5 . PubMed

Redlich K., Gortz B., Hayer S., Zwerina J., Doerr N., Kostenuik P., Bergmeister H., Kollias G., Steiner G., Smolen J. S., Schett G., 2004, "Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis", Am. J. Pathol., 164 (2), 543-55 . PubMed

Gortz B., Hayer S., Redlich K., Zwerina J., Tohidast-Akrad M., Tuerk B., Hartmann C., Kollias G., Steiner G., Smolen J. S., Schett G., 2004,  "Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation", J. Bone Miner. Res., 19 (6), 990-8 . PubMed

Douni E., Alexiou M., Kollias G., 2004, "Genetic engineering in the mouse: tuning TNF/TNFR expression", Methods Mol. Med., 98, 137-70 . PubMed

Zwerina J., Hayer S., Tohidast-Akrad M., Bergmeister H., Redlich K., Feige U., Dunstan C., Kollias G., Steiner G., Smolen J., Schett G., 2004, "Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: Effects on synovial inflammation, bone erosion, and cartilage destruction", Arthritis Rheum., 50, 277-90 . PubMed

Douni E., Sfikakis P. P., Haralambous S., Fernandes P., Kollias G., 2004, "Attenuation of inflammatory polyarthritis in TNF transgenic mice by diacerein: comparative analysis with dexamethasone, methotrexate and anti-TNF protocols", Arthritis Res. & Ther., 6 (1), R65-R72 . PubMed

Mershin A., Pavlopoulos E., Fitch O., Braden B. C., Nanopoulos D. V., Skoulakis E., 2004, "Learning and memory deficits upon TAU accumulation of in Drosophila mushroom body neurons", Learning and Memory, 11, 277-287 . PubMed

Nemazanyy I., Panasyuk G., Zhyvoloup A., Panayotou G., Gout I. T., Filonenko V., 2004, "Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism", FEBS Lett., 578, 357-362 . PubMed


Sidera K., Samiotaki M., Yfanti E., Panayotou G., Patsavoudi E., 2004, "Involvement of cell surface HSP90 in cell migration reveals a novel role in the developing nervous system", J. Biol. Chem., 279, 45379-45388 PubMed


Ponnuraj K, Xu Y, Macon K, Moore D, Volanakis JE, Narayana SV. 2004 "Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase".Mol Cell. 2004 Apr 9;14(1):17-28. PubMed

Panayotou G., 2004, "Molecular analysis of signal transduction pathways", Autoimmun. Rev., 3, S28-9 . PubMed

Foukas L. C., Panayotou G., Shepherd P. R., 2004, "Direct interaction of MHC class II derived peptides with class Ia PI 3-kinase results in dose-dependent stimulatory effects", J. Biol. Chem., 279, 7505-7511. PubMed