Position ArchiveThe Kontoyiannis’ lab is seeking highly motivated applicants for one (1) pre-doctoral position in bioinformatics to support a national project (ARISTEIA I) entitled “Post-transcriptional determination of inflammatory states: coupling ribonomes to signaling adaptors”. The program is covered by the Operational Program “Education & Lifelong Learning” and is co-funded by the European Union (European Social Fund) and national funds. The project aims to identify post-transcriptional networks of mRNA usage that determine the plasticity of innate immune subsets; it encompasses a variety of methodologies to assess ribonucleoprotein interactions in vivo and in the context of transgenic permutations. Research under this program will take place in the facilities of BSRC”Alexander Fleming”, at Vari, Attiki, Greece and for a period of 36 months-starting immediatelly.
Applicants should hold BSc and MSc in bioinformatics and computational biology. The project involves the development and/or application of algorithmic platforms for the analysis of data derived from high-throughput sequencing platforms for the identification of cis-element/miRNA/RNA-binding protein relationships and modelling of data behaviour in the context of prototypical immune reactions. Prior experience is those areas will be beneficial.
All applicants should send a full CV along with a short presentation of their qualifications/interests and the names of three referees at
Relevant Publications:
- Kafasla P, Karakasiliotis I, Kontoyiannis DL 2012, "Decoding the functions of post-transcriptional regulators in the determination of inflammatory states: focus on macrophage activation.", Wiley Interdiscip Rev Syst Biol Med. , 2012 Jul 3. , doi: 10.1002/wsbm.1179.
- Yiakouvaki A., et al. (2012). Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis. J. Clin. Investigation. 122:48-61
- Katsanou V, et al. (2005). HuR as a negative posttranscriptional modulator in inflammation. Mol. Cell 19:777-789.
More lab information & publications at : http://www.fleming.gr/research/immunology/kontoyiannis-lab
More info in Greek.