The scientists at BSRC “Alexander Fleming” perform cutting-edge research, aiming to understand molecular mechanisms of complex biological processes in health and disease. We are also committed to contribute to innovation in medicine, by developing novel therapeutic and diagnostic methods, focusing on immunity and inflammation, cancer, and neurodegenerative diseases. To keep our focus on top-notch research, we recruit at all levels with excellence as the sole criterion and we support our researchers by providing state-of-the science infrastructures and a pleasant working environment. FLEMING is a non-profit organization operating under the auspices of the Greek General Secretariat for Research & Technology and is supported by the Greek government and by national, European and international grants.
Papanikolopoulou & Skoulakis demonstrate that Tau-mediated neuronal dysfunction and toxicity are separable and in fact neuronal dysfunction, which requires phosphorylation on Ser262, precedes and is required for Ser238 phosphorylation which in turn is requisite for premature lethality. PubMed
Dr Antigone Dimas, Marie-Curie and EMBO Research Fellow at BSRC Alexander Fleming, was awarded this year’s L’Oréal-UNESCO Award for Women in Science. This prestigious award rewards promising young women scientists whose outstanding achievements have contributed to the advancement of scientific knowledge.
Recent work by Fleming researchers indicate that in liver tumors, cancer stem cells may originate from differentiating ductal progenitors following oncogenic transformation. PubMed .
Infrafrontier-GR/Phenotypos, the Greek Research Infrastructure for molecular and behavioural Phenotyping of biological model organisms for chronic degenerative diseases, which is coordinated by Fleming, has been included in the new National Roadmap for Research infrastructures that has just been launched by the General Secretariat for Research and Technology.
Seminar 18-12-2014, 13.00. "Bioinformatics analysis for exome and large panel high-throughput sequencing", Andreas Massouras, PH.D., SAPHETOR, EPFL Innovation Park, Lausanne, Switzerland
Seminar 17-12-2014, 13.00. "Systemic approaches for understanding brain disorders", Michaela Filiou, Ph.D., Max Planck Institute of Psychiatry, Munich, Germany