The scientists at BSRC “Alexander Fleming” perform cutting-edge research, aiming to understand molecular mechanisms of complex biological processes in health and disease. We are also committed to contribute to innovation in medicine, by developing novel therapeutic and diagnostic methods, focusing on immunity and inflammation, cancer, and neurodegenerative diseases. To keep our focus on top-notch research, we recruit at all levels with excellence as the sole criterion and we support our researchers by providing state-of-the science infrastructures and a pleasant working environment. FLEMING is a non-profit organization operating under the auspices of the Greek General Secretariat for Research & Technology and is supported by the Greek government and by national, European and international grants.
In a study published this week in PNAS, Fleming researchers uncover a novel mechanism that exists to physiologically protect the intestinal epithelium against damage and when dysregulated, it may underlie the development of Inflammatory Bowel Diseases in humans. The study is highlighted in Nat. Rev. Gastroenterol. Hepatol. and Faculty of 1000.
Work from Kontoyiannis Lab presented in Cell Death and Differentiation suggests that specific RNA-binding proteins (RBPs) of the Elavl family are required to confer protection from neurodegeneration.
In a study published this week at the BMC Genomics journal researchers of the Division of Molecular Biology and Genetics and the FLEMING's Genomics Facility, in close collaboration with the University of Thessaly, helped to uncover a novel aspect of insecticide resistance in the olive fly, the most devastating pest of cultivated olives.
Seminar 11-11-2014, 15.00. "Interplay between Transcription Factors and DNA methylation Changes in Myeloid Differentiation", Esteban Ballestar, Ph.D, Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain