Molecular Biologist Position – Functional Genomics Lab (23-11-2012)

The Functional Genomics Lab at BSRC Alexander Fleming is seeking highly motivated applicants for a postdoctoral position in molecular genetics to support a national project (Synergasia II) entitled “Detection of new breast and ovarian cancer predisposing alleles using whole genome next generation sequencing”. The program is covered by the Operational Program “Education and Lifelong Learning” and is co-funded by the European Union (European Social Fund) and national funds. Research under this program will take place in the facilities of BSRC Alexander Fleming, at Vari, Attiki, Greece, for a period of 30 months starting January 2013.

Applicants should have a strong publication record and should hold a PhD in molecular biology, genetics or a related field. The ideal candidate will have experience in laboratory techniques including next-generation sequencing, nucleic acid extraction, PCR, RT-PCR, and chromatin immunoprecipitation. Training and research experience in bioinformatic programming, statistics and large-scale sequence analysis is highly desirable. The project involves the development and application of next generation sequencing technology to identify novel genetic risk factors for breast and ovarian cancer. Prior research experience in these fields would be beneficial.

Applicants should send a) a full curriculum vitae, b) a short presentation of their qualifications and research interests, and c) the names of three referees to Prof Ioannis Ragoussis ( This email address is being protected from spambots. You need JavaScript enabled to view it. ) and to Dr Antigone Dimas ( This email address is being protected from spambots. You need JavaScript enabled to view it. ). Deadline: 31 December 2012.

Relevant Publications:

Buffa, F., Camps, C., Winchester, L., Gee, H., Shaeldon, H., Taylor, M., Harris, A., Ragoussis, J. (2011) miRNAs associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Research 71, 5635-5645

Camps C., Buffa F. M., Colella S., Moore J., Sotiriou C., Sheldon H., Harris A. L., Gleadle J. M., and Ragoussis J. (2008). hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer. Clin Cancer Res 14: 1340-8.

Lise, S.; Jackson, M., Kwasniewska, A., Clarkson, Y., Perkins E., Sadighi Akha, E., Gregory, L., Green. A., Allan, C., Lamble, S., Jayawant, S., Cader, M.Z., Quaghebeur, G., Kanapin, A., Rimmer, A., Lunter, G., Cazier, J.B., Taylor, J., Bentley, D., McVean, G., Donnelly, P., Knight, S.J., Ragoussis, J. & Nemeth, A.H. Recessive mutations in SPTBN2 cause dysequilibrium syndrome and implicate β-III spectrin in both cortical and cerebellar function (2012). Plos Genet. in press

More info in Greek.

B.S.R.C. "Alexander Fleming"
34 Fleming Street, 16672 Vari, Greece
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