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George Kollias' research group

Publications

2010

Viejo-Borbolla A, Martin AP, Muniz LR, Shang L, Marchesi F, Thirunarayanan N, Harpaz N, Garcia RA, Apostolaki M, Furtado GC, Mayer L, Kollias G, Alcami A, Lira SA. 2010, "Attenuation of TNF-driven murine ileitis by intestinal expression of the viral immunomodulator CrmD.", Mucosal Immunol. , 2010 Jul 21., [Epub ahead of print] [PubMed].

Zouberakis M, Chandras C, Swertz M, Smedley D, Gruenberger M, Bard J, Schughart K, Rosenthal N, Hancock JM, Schofield PN, Kollias G, Aidinis V 2010, "Mouse Resource Browser--a database of mouse databases.", Database (Oxford). , Jul 6 2010, baq010. [PubMed].

Zaiss MM, Frey B, Hess A, Zwerina J, Luther J, Nimmerjahn F, Engelke K, Kollias G, Hünig T, Schett G, David JP. 2010, "Regulatory T cells protect from local and systemic bone destruction in arthritis.", J Immunol. , 2010 Jun 15 , 184(12):7238-46. Epub 2010 May 17 [PubMed].

Blüml S, Binder NB, Niederreiter B, Polzer K, Hayer S, Tauber S, Schett G, Scheinecker C, Kollias G, Selzer E, Bilban M, Smolen JS, Superti-Furga G, Redlich K.. 2010, "Anti-inflammatory effects of TNF on hematopoietic cells in the development of erosive arthritis.", Arthritis Rheum., 2010 Feb 12. , Epub ahead of print [PubMed].

Apostolaki M, Armaka M, Victoratos P, Kollias G. 2010, "Cellular Mechanisms of TNF Function in Models of Inflammation and Autoimmunity.", Curr Dir Autoimmun., 2010;11:1-26, Epub 2010 Feb 18. [PubMed].

Jacques P, Venken K, Van Beneden K, Hammad H, Seeuws S, Drennan MB, Deforce D, Verbruggen G, Apostolaki M, Kollias G, Lambrecht BN, De Vos M, Elewaut D. 2010, "Invariant natural killer T cells are natural regulators of spondyloarthritis.", Arthritis Rheum., 2010 Jan 21. , Epub ahead of print [PubMed].

Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J, Wood J, EUMODIC Consortium , de Angelis MH, Brown SD, Hancock JM, Mallon AM., 2010, "EuroPhenome: a repository for high-throughput mouse phenotyping data.", Nucleic Acids Res, 2010 Jan;38(Database issue):, D577-85. Epub 2009 Nov 23.; [PubMed].

2009

Christina Chandras, Thomas Weaver, Michael Zouberakis, Damian Smedley, Klaus Schughart, Nadia Rosenthal, John M. Hancock, George Kollias, Paul N. Schofield, and Aidinis V., 2009, "Models for financial sustainability of biological databases and resources ", Database (2009), Vol. 2009, , bap017; [PubMed].

Böhm C, Hayer S, Kilian A, Zaiss MM, Finger S, Hess A, Engelke K, Kollias G, Krönke G, Zwerina J, Schett G, David JP. , 2009, "The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss.", J Immunol. , 2009 Nov 1 183(9):5938-47. Epub 2009 Oct 14 [Pubmed]

Johansen C, Vestergaard C, Kragballe K, Kollias G, Gaestel M, Iversen L., 2009, "MK2 regulates the early stages of skin tumor promotion.", Carcinogenesis, 2009 Oct 6. [Epub ahead of print] [Pubmed]

Thwin MM, Douni E, Arjunan P, Kollias G, Kumar PV, Gopalakrishnakone P. 2009, "Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice.", Arthritis Res Ther., 2009 Sep 18;11(5):R138. [Epub ahead of print] , [PubMed]

Charles KA, Kulbe H, Soper R, Escorcio-Correia M, Lawrence T, Schultheis A, Chakravarty P, Thompson RG, Kollias G, Smyth JF, Balkwill FR, Hagemann T. 2009, "The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans.", J Clin Invest., 2009 Sep 8. pii: 39065. doi: 10.1172/JCI39065. [Epub ahead of print] , [PubMed]

Afantitis A, Melagraki G, Sarimveis H, Koutentis PA, Igglessi-Markopoulou O and Kollias G, 2009, "A combined LS-SVM & MLR QSAR workflow for predicting the inhibition of CXCR3 receptor by quinazolinone analogs", Mol Divers, 2009 May 30. [Epub ahead of print] .[Pubmed]

Sotiria Tzima, Panayiotis Victoratos, Ksanthi Kranidioti, Maria Alexiou and George Kollias, 2009, "Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production", J Exp Med, doi:10.1084/jem.20081582 .[Pubmed]

Maria Armaka, Vassiliki Gkretsi, Dimitris Kontoyiannis and George Kollias, 2009, "A standardized protocol for the isolation and culture of normal and arthritogenic murine synovial fibroblasts .", Nature Protocols , DOI: 10.1038/nprot.2009.102 .[Nature Protocols]

Melagraki G, Afantitis A, Sarimveis H, Koutentis PA, Kollias G, Igglessi-Markopoulou O. 2009, "Predictive QSAR workflow for the in silico identification and screening of novel HDAC inhibitors.", Mol Divers. , [Epub ahead of print], [PubMed].

Huang CH, Vallejo JG, Kollias G, Mann DL. 2009, "Role of the Innate Immune System in Acute Viral Myocarditis.", Basic Res Cardiol. , [Epub ahead of print], [PubMed].

Victoratos P, Kollias G . 2009, "Induction of autoantibody-mediated spontaneous arthritis critically depends on follicular dendritic cells.", Immunity , 30(1):130-42 , [PubMed].

2008

Gareus R, Kotsaki E, Xanthoulea S, van der Made I, Gijbels MJ, Kardakaris R, Polykratis A,, Kollias G, de Winther MP, Pasparakis M. 2008, "Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis.", Cell Metab. , 2008 Nov;8(5):372-83, [PubMed].

Büning J, von Smolinski D, Tafazzoli K, Zimmer KP, Strobel S, Apostolaki M, Kollias G, Heath JK, Ludwig D, Gebert A. 2008, "Multivesicular bodies in intestinal epithelial cells: responsible for MHC class II-restricted antigen processing and origin of exosomes.", Immunology. , 2008 Aug 14. [Epub ahead of print], [PubMed].

Ermolaeva MA, Michallet MC, Papadopoulou N, Utermöhlen O, Kranidioti K, Kollias G, Tschopp J, Pasparakis M. 2008, "Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses.", Nat Immunol. , 2008 Sep;9(9):1037-46. Epub 2008 Jul 20, [Pubmed].

Allie N, Alexopoulou L, Quesniaux VJ, Fick L, Kranidioti K, Kollias G, Ryffel B, Jacobs M. 2008, "Protective role of membrane tumour necrosis factor in the host's resistance to mycobacterial infection.", Immunology, 2008 Jun 9, [Pubmed].

Pullerits R, Jonsson IM, Kollias G, Tarkowski A. 2008, "Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling.", Arthritis Res Ther, 2008;10(3):R72, [Pubmed].

Antreas Afantitis, Georgia Melagraki, Haralambos Sarimveis, Olga Igglessi-Markopoulou, Kollias G, 2008, "A novel QSAR model for predicting the inhibition of CXCR3 receptor by 4-N-aryl-[1,4]diazepane ureas", European Journal of Medicinal Chemistry, 2008.05.028, [ScienceDirect].

Apostolaki M, Manoloukos M, Roulis M, Wurbel MA, Müller W, Papadakis KA, Kontoyiannis DL, Malissen B, Kollias G, 2008, "Role of beta7 Integrin and the Chemokine/Chemokine Receptor Pair CCL25/CCR9 in Modeled TNF-Dependent Crohn's Disease", Gastroenterology., 2008 Mar 5, Epub ahead of print [PubMed].

Huybers S, Apostolaki M, van der Eerden BC, Kollias G, Naber TH, Bindels RJ, Hoenderop JG. 2008, "Murine TNF(DeltaARE) Crohn's disease model displays diminished expression of intestinal Ca(2+) transporters", Inflamm Bowel Dis., 2008 Feb 11, Epub ahead of print [PubMed].

Maria Armaka, Maria Apostolaki, Peggy Jacques, Dimitris L. Kontoyiannis, Dirk Elewaut, Kollias G. 2008, "Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases", J Exp Med, 2008 Feb 4, 10.1084/jem.20070906 [PubMed].

Schurigt U, Hummel KM, Petrow PK, Gajda M, Stöckigt R, Middel P, Zwerina J, Janik T, Bernhardt R, Schüler S, Scharnweber D, Beckmann F, Saftig P, Kollias G ,Schett G, Wiederanders B, Bräuer R. 2008, "Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice.", Arthritis Rheum., 2008 Jan 31, 58(2):422-434 [PubMed].

Bobacz K, Sunk IG, Hayer S, Amoyo L, Tohidast-Akrad M, Kollias G ,Smolen JS, Schett G. 2008, "Differentially regulated expression of growth differentiation factor 5 and bone morphogenetic protein 7 in articular cartilage and synovium in murine chronic arthritis: Potential importance for cartilage breakdown and synovial hypertrophy.", Arthritis Rheum., 2008 Jan, 58(1):109-18 [PubMed].

2007

Vasilopoulos Y, Gkretsi V, Armaka M, Aidinis V, Kollias G 2007, "Actin cytoskeleton dynamics linked to synovial fibroblast activation as a novel pathogenic principle in TNF-driven arthritis.", Ann Rheum Dis., 2007 Nov, 66 Suppl 3:iii23-8 [PubMed].

Douni E, Armaka M, Kontoyiannis DL, Kollias G 2007, "Functional genetic and genomic analysis of modeled arthritis.", Adv Exp Med Biol., 2007, 602:33-42. [PubMed in process].

Van Molle W, Van Roy M, Van Bogaert T, Dejager L, Van Lint P, Vanlaere I, Sekikawa K, Kollias G , Libert C. 2007, "Protection of zinc against tumor necrosis factor induced lethal inflammation depends on heat shock protein 70 and allows safe antitumor therapy.", Cancer Res., 2007 Aug 1, 67(15):7301-7. [PubMed].

Chatzidakis I, Fousteri G, Tsoukatou D, Kollias G , Mamalaki C. 2007, "An essential role for TNF in modulating thresholds for survival, activation, and tolerance of CD8+ T cells.", J Immunol., 2007 Jun 1, 178(11):6735-45. [PubMed].

The Mouse Phenotype Database Integration Consortium ( John M. Hancock, Niels C. Adams, Aidinis V., Andrew Blake, Judith A. Blake, Molly Bogue, Steve D. M. Brown, Elissa Chesler, Duncan Davidson, Christopher Duran, Janan T. Eppig, Valerie Gailus-Durner, Hilary Gates, Georgios V. Gkoutos, Simon Greenaway, Martin Hrabe´ De Angelis, Kollias George, Sophie Leblanc, Kirsty Lee, Christoph Lengger, Holger Maier, Ann-Marie Mallon, Hiroshi Masuya, David G. Melvin, Werner Mu ller, Helen Parkinson, Glenn Proctor, Eli Reuveni, Paul Schofield, Aadya Shukla, Cynthia Smith, Tetsuro Toyoda, Laurent Vasseur, Shigeharu Wakana, Alison Walling, Jacqui White, Joe Wood, Michalis Zouberakis) , 2007, "Integration of mouse phenome data resources", Mamm. Genome., 18(3):157-63., [Pubmed].

Ye P, Kollias G , D'Ercole AJ. 2007, "Insulin-like growth factor-I ameliorates demyelination induced by tumor necrosis factor-alpha in transgenic mice.", J Neurosci Res., 2007 Feb 5, 85(4):712-722 [Epub ahead of print] [PubMed].

2006

Alexopoulou L, Kranidioti K, Xanthoulea S, Denis M, Kotanidou A, Douni E, Blackshear PJ, Kontoyiannis DL, Kollias G  2006, "Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity.", Eur J Immunol., 2006 Oct, 36(10):2768-80 [PubMed].

Boillee S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G ,Cleveland DW, 2006, "Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia.", Science, 2006 Jun 2, 312(5778):1389-92 [PubMed].

Bamias G, Mishina M, Nyce M, Ross WG, Kollias G Rivera-Nieves J, Pizarro TT, Cominelli F, 2006, "Role of TL1A and its receptor DR3 in two models of chronic murine ileitis.", Proc Natl Acad Sci U S A., 2006 May 30, 103(22):8441-6 [PubMed].

Argyropoulos C, Chatziioannou AA, Nikiforidis G, Moustakas A, Kollias G ,Aidinis V., 2006, "Operational criteria for selecting a cDNA microarray data normalization algorithm.", Oncol rep., 2006, 15:983-996 [PubMed].

Zwerina J, Hayer S, Redlich K, Bobacz K, Kollias ,Smolen JS, Schett G.
, 2006, "Activation of p38 MAPK is a key step in tumor necrosis factor-mediated inflammatory bone destruction.", Arthritis Rheum., 2006 Jan 30, 54(2):463-472 [PubMed].

Victoratos P, Lagnel J, Tzima S, Alimzhanov MB, Rajewsky K, Pasparakis M, Kollias , 2006, "FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses. ", Immunity., 2006 Jan, 24(1):65-77. [PubMed].

 

2005

Hayer S, Tohidast-Akrad M, Haralambous S, Jahn-Schmid B, Skriner K, Trembleau S, Dumortier H, Pinol-Roma S, Redlich K, Schett G, Muller S, Kollias , Smolen J, Steiner G., 2005, "Aberrant expression of the autoantigen heterogeneous nuclear  ribonucleoprotein-A2 (RA33) and spontaneous formation of rheumatoid arthritis-associated anti-RA33 autoantibodies in TNF-alpha transgenic mice.", J Immunol., 2005 Dec 15, 175(12):8327-36. [PubMed].

Beardmore VA, Hinton HJ, Eftychi C, Apostolaki M, Armaka M, Darragh J, McIlrath J, Carr JM, Armit LJ, Clacher C, Malone L, Kollias G, Arthur JS.,, 2005, "Generation and Characterization of p38{beta} (MAPK11) Gene-Targeted Mice", Mol Cell Biol., 2005 Dec, 25(23):10454-10464 [PubMed].

Aidinis V, Carninci P, Armaka M, Witke W, Harokopos V, Pavelka N, Koczan D, Argyropoulos C, Thwin MM, Moller S, Kazunori W, Gopalakrishnakone P, Ricciardi-Castagnoli P, Thiesen HJ, Hayashizaki Y,Kollias G, 2005, "Cytoskeletal rearrangements in synovial fibroblasts as a novel pathophysiological determinant of modeled rheumatoid arthritis", PLoS Genet., 2005 Oct, 1(4):e48 [PubMed].

Hovelmeyer N, Hao Z, Kranidioti K, Kassiotis G, Buch T, Frommer F, von Hoch L, Kramer D, Minichiello L, Kollias G , Schett G., 2005, "Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune Encephalomyelitis ", J Immunol., 2005 Nov 1;175(9), 5875-84 [PubMed].

Zwerina J, Tzima S, Hayer S, Redlich K, Hoffmann O, Hanslik-Schnabel B, Smolen JS, Kollias G , Lassmann H, Waisman A., 2005, "Heme oxygenase 1 (HO-1) regulates osteoclastogenesis and bone resorption, FASEB J., 2005 Oct 18,  [PubMed].

Katsanou V, Papadaki O, Milatos S, Blackshear PJ, Anderson P, Kollias G., Kontoyiannis DL., 2005, "HuR as a negative posttranscriptional modulator in inflammation", Mol Cell., 2005 Sep 16;19(6):, 777-89 [PubMed].

Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H Kollias G., Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schonbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y; FANTOM Consortium; RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)., 2005, "The transcriptional landscape of the mammalian genome", Science 2005 Sep 2;309(5740), 1559-63 [PubMed].

Kollias G., 2005, "TNF pathophysiology in murine models of chronic inflammation and autoimmunity", Semin Arthritis Rheum., 2005 Apr;34(5 Suppl1), 3-6. Review. [PubMed].

 

2004

Panagopoulos D., Victoratos P., Alexiou M., Kollias G., Mosialos G., 2004, "Comparative analysis of signal transduction by CD40 and the Epstein-Barr Virus Oncoprotein LMP1 in vivo", J. Virol., 78 (3), 13253-61 [PubMed].

Staelens J., Puimege L., Mahieu T., Pynaert G., Hochepied T., Vandenabeele A., Grooten J., Kontoyiannis D., Van Roy F., Kollias G., Libert C., 2004, "Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders", Mamm. Genome., 15, 537-543 [PubMed].

Auwerx J., Avner P., Baldock R., Ballabio A., Balling R., Barbacid M., Berns A., Bradley A., Brown S., Carmeliet P., Chambon P., Cox R., Davidson D., Davies K., Duboule D., Forejt J., Granucci F., Hastie N., de Angelis M. H., Jackson I., Kioussis D., Kollias G., Lathrop M., Lendahl U., Malumbres M., von Melchner H., Muller W., Partanen J., Ricciardi-Castagnoli P., Rigby P., Rosen B., Rosenthal N., Skarnes B., Stewart AF, Thornton J., Tocchini-Valentini G., Wagner E., Wahli W., Wurst W., 2004, "The European dimension for the mouse genome mutagenesis program", Nat. Genetics, 36, 925-7 [PubMed].

Smolen J. S., Hayer S., Schett G., Redlich K., Aringer M., Kollias G., Wagner E., Steiner G., 2004, "Autoimmunity and rheumatoid arthritis", Autoimmun. Rev., 3 Suppl 1, S23 [PubMed].

Kollias G., 2004, "Modeling the function of tumor necrosis factor in immune pathophysiology", Autoimmun. Rev., 3 Suppl 1, S24-5 [PubMed].

Xanthoulea S., Pasparakis M., Kousteni S., Brakebusch C., Wallach D., Bauer J., Lassmann H., Kollias G., 2004, "Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases", J. Exp. Med., 2;200 (3), 367-76 [PubMed].

Herrak P., Gortz B., Hayer S., Redlich K., Reiter E., Gasser J., Bergmeister H., Kollias G., Smolen J. S., Schett G., 2004, "Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis", Arthritis Rheum., 50 (7), 2327-37 [PubMed].

Thwin M. M., Douni E., Aidinis V., Kollias G., Kodama K., Sato K., Satish R. L., Mahendran R., Gopalakrishnakone P., 2004, "Effect of phospholipase A2 inhibitory peptide on inflammatory arthritis in a TNF transgenic mouse model: a time-course ultrastructural study", Arthritis Res. & Ther., 6 (3), R282-94 [PubMed].

Gortz B., Hayer S., Redlich K., Zwerina J., Tohidast-Akrad M., Tuerk B., Hartmann C., Kollias G., Steiner G., Smolen J. S., Schett G., 2004, "Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation", J. Bone Miner. Res., 19 (6), 990-8 [PubMed].

Douni E., Alexiou M., Kollias G., 2004, "Genetic engineering in the mouse: tuning TNF/TNFR expression", Methods Mol. Med., 98, 137-70 [PubMed].

Redlich K., Gortz B., Hayer S., Zwerina J., Kollias G., Steiner G., Smolen J. S., Schett G., 2004, "Overexpression of tumor necrosis factor causes bilateral sacroiliitis", Arthritis Rheum., 50 (3), 1001-5 [PubMed].

Douni E., Sfikakis P. P., Haralambous S., Fernandes P., Kollias G., 2004, "Attenuation of inflammatory polyarthritis in TNF transgenic mice by diacerein: comparative analysis with dexamethasone, methotrexate and anti-TNF protocols", Arthritis Res. & Ther., 6 (1), R65-R72 [PubMed].

Redlich K., Gortz B., Hayer S., Zwerina J., Doerr N., Kostenuik P., Bergmeister H., Kollias G., Steiner G., Smolen J. S., Schett G., 2004, "Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis", Am. J. Pathol., 164 (2), 543-55 [PubMed].

Zwerina J., Hayer S., Tohidast-Akrad M., Bergmeister H., Redlich K., Feige U., Dunstan C., Kollias G., Steiner G., Smolen J., Schett G., 2004, "Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: Effects on synovial inflammation, bone erosion, and cartilage destruction", Arthritis Rheum., 50, 277-90 [PubMed].

2003

Schett G., Redlich K., Hayer S., Zwerina J., Bolon B., Dunstan C., Gortz B., Schulz A., Bergmeister H., Kollias G., Steiner G., Smolen J. S., 2003, "Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice", Arthritis Rheum., 48, 2042-51 [PubMed].

Sfikakis P. P., Kollias G., 2003, "Tumor necrosis factor biology in experimental and clinical arthritis", Curr. Op. Rheumatol., 15, 380-6 [PubMed].

Probst H. C., Lagnel J., Kollias G., van den Broek M., 2003, "Inducible transgenic mice reveal resting dentritic cells as potent inducers of CD8+ T cell tolerance", Immunity, 18, 713-720 [PubMed].

Aidinis V., Plows D., Haralambous S., Armaka M., Papadopoulos P., Kanaki M. Z., Koczan D., Thiessen H. J., Kollias G., 2003, "Functional analysis of an arthritogenic synovial fibroblast", Arthritis Res. & Ther., 5, 140-157 [PubMed].

Hukkanen M., Platts L. A., Haralambous S., Ainola M., Konttinen Y. T., Kollias G., Polak J. M., 2003, "Induction of Inducible Nitric Oxide Synthase, Argininosuccinate Synthase, and GTP Cyclohydrolase I in Arthritic Joints of Human Tumor Necrosis Factor-a Transgenic Mice", J. Rheumatol., 30, 652-9 [PubMed].

Ye P., Price W., Kassiotis G., Kollias G., D'Ercole A. J., 2003, "Tumor necrosis factor-alpha regulation of insulin-like growth factor-I, type 1 IGF receptor, and IGF binding protein expression in cerebellum of transgenic mice", J. Neurosci. Res., 71, 721-31 [PubMed].

Akassoglou K., Douni E., Bauer J., Lassmann H., Kollias G., Probert L., 2003, "Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice", Proc. Natl. Acad. Sci. U.S.A., 100, 709-714 [PubMed].

2002

Holtmann M. H., Douni E., Schutz M., Zeller G., Mudter J., Lehr H. A., Gerspach J., Scheurich P., Galle P. R., Kollias G., Neurath M. F., 2002, "Tumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn's disease and promotes experimenta colitis in vivo", Eur. J. Immunol., 32, 3142-51 [PubMed].

Kontoyiannis D., Boulougouris G., Manoloukos M., Armaka M., Apostolaki M., Pizzaro T., Kotlyarov A., Forster I., Flavell R., Gaestel M., Tsichlis P., Cominelli F., Kollias G., 2002, "Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease", J. Exp. Med., 196, 1563-74 [PubMed].

Redlich K., Hayer S., Ricci R., David J.-P., Tohidast-Akrad M., Kollias G., Steiner G., Smolen G. S., Wagner E. F., Schett G., 2002, "Oscteoclasts are essential for TNF-α-mediated joint destruction", J. Clin. Invest., 110, 1419-1427 [PubMed].

Kollias G., Kontoyiannis D., 2002, "Role of TNF/TNFR in autoimmunity: specific TNF receptor blockade may be advantageous to anti-TNF treatments", Cytokine Growth Factor Rev., 13, 315-321 [PubMed].

Redlich K., Hayer S., Maier A., Dunstan C. R., Tohidast-Akrad M., Lang S., Turk B., Pietschmann P., Woloszezuk W., Haralambous S., Kollias G., Steiner G., Smolen J. S., Schett G., 2002, "Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin", Arthritis Rheum., 46, 785-92 [PubMed].

Kollias G., Kontoyiannis D., Douni E., Kassiotis G., 2002, "The role of TNF/TNFR in organ-specific and systemic autoimmunity: implications for the design of optimized 'anti-TNF' therapies", Curr. Dir. Autoimmun., 5, 30-50 [PubMed].

Neininger A., Kontoyiannis D., Kotlyarov A., Winzen R., Eckert R., Volk H.-D., Holtmann H., Kollias G., Gaestel M., 2002, "MK2 targets AU-rich elements and regulates biosynthesis of Tumor Necrosis Factor and Interleukin-6 independently at different post-transcriptional levels", J. Biol. Chem., 277, 3065-3068 [PubMed].

2001

Schett G., Hayer S., Tohidast-Akrad M., Jahn Schmid B., Lang S., Turk B., Kainberger F., Kollias G., Newby A. C., Xu Q., Steiner G., Smolen J., 2001, "Adenoviral-based overexpression of TIMP-1 reduces tissue damage in the joints of TNFα-transgenic mice", Arthritis Rheum., 44, 2888-98 [PubMed].

Kassiotis G., Kranidioti K., Kollias G., 2001, "Defective CD4T cell priming and resistance to experimental autoimmune encephalomyelitis in TNF-deficient mice due to innate immune hypo-responsiveness", J. Neuroimmunol., 119, 239-47 [PubMed].

Kontoyiannis D., Kotlyarov A., Carballo E., Alexopoulou L., Blackshear P. J., Gaestel M., Davis R., Flavell R., Kollias G., 2001, "Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology", EMBO J., 20, 3760-3770 [PubMed].

Bezzi P., Domercq M., Brambilla L., Galli R., Schols D., De Clercq E., Vescovi A., Bagetta G., Kollias G., Meodolesi J., Volterra A., 2001, "CXCR4-activated astrocyte glytamate release via TNFα: amplification by microglia triggers neurotoxicity", Nat. Neurosci., 4, 702-10 [PubMed].

Kassiotis G., Kollias G., 2001, "TNF and receptors in organ-specific autoimmune disease: multi-layered functioning mirrored in animal models", J. Clin. Invest., 107, 1507-8 [PubMed].

Kassiotis G., Kollias G., 2001, "Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination", J. Exp. Med., 193, 427-434 [PubMed].

2000

Dumitru C. D., Ceci J. D., Tsatsanis C., Kontoyiannis D., Stamatakis K., Lin J. H., Patriotis C., Jenkins N. A., Copeland N. G., Kollias G., Tsichlis P. N., 2000, "TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway", Cell, 103, 1071-1083 [PubMed].

Kontoyiannis D., Kollias G., 2000, "Fibroblast biology: Synovial fibroblasts in rheumatoid arthritis: leading role or chorus line?", Arthritis Res., 2, 342-3 [PubMed].

Biedermann T., Kneilling M., Mailhammer R., Maier K., Sander C. A., Kollias G., Kunkel S. L., Hultner L., Rocken M., 2000, "Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2", J. Exp. Med., 192, 1441-52 [PubMed].

Kontoyiannis D., Kollias G., 2000, "Accelerated autoimmunity and lupus nephritis in NZB mice with engineered heterozygous deficiency in tumor necrosis factor", Eur. J. Immunol., 30, 2038-47 [PubMed].

Schwarz E. M., Lu A. P., Goater J. J., Benz E. B., Kollias G., Rosier R. N., Puzas J. E., O'Keefe R. J., 2000, "Tumor necrosis factor-alpha/nuclear transcription factor-kappaB signaling in periprosthetic osteolysis", J. Orthop. Res., 18, 472-80 [PubMed].

Liefner M., Siebert H., Sachse T., Michel U., Kollias G., Bruck W., 2000, "The role of TNF-alpha during Wallerian degeneration", J. Neuroimmunol., 108, 147-52 [PubMed].

Abu-Amer Y., Erdmann J., Alexopoulou L., Kollias G., Ross F. P., Teitelbaum S. L., 2000, "Tumor necrosis factor receptors types 1 and 2 differentially regulate osteoclastogenesis", J. Biol. Chem., 275, 27307-27310 [PubMed].

White D. W., Badovinac V. P., Kollias G., Harty J. T., 2000, "Cutting Edge: Antilisterial activity of CD8+T cells derived from TNF-deficient and TNF/perforin double-deficient mice", J. Immunol., 165, 5-9 [PubMed].

Pasparakis M., Kousteni S., Peschon J., Kollias G., 2000, "Tumor necrosis factor and the p55TNF receptor are required for optimal development of the marginal sinus and for migration of follicular dendritic precursors into splenic follicles", Cell. Immunol., 201, 33-41 [PubMed].

Goater J., Muller R., Kollias G., Firestein G. S., Sanz I., O'Keefe R. J., Schwarz E. M., 2000, "Empirical advantages of adeno associated viral vectors in vivo gene therapy for arthritis", J. Rheumatol., 27, 983-9 [PubMed].

Iyler S., Kontoyiannis D., Chevrier D., Woo J., Mori N., Cornejo M., Kollias G., Buelow R., 2000, "Inhibition of tumor necrosis factor mRNA translation by a rationally designed immunomodulatory peptide", J. Biol. Chem., 275, 17051-7 [PubMed].

Mabbott N. A., Williams A., Farquhar C. F., Pasparakis M., Kollias G., Bruce M. E., 2000, "Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie", J. Virol., 74, 3338-44 [PubMed].

1999

Akassoglou K., Bauer J., Kassiotis G., Lassmann H., Kollias G., Probert L., 1999, "Transgenic models of TNF induced demyelination", Adv. Exp. Med. Biol., 468, 245-259 [PubMed].

Van den Berg W. B., Joosten L. A., Kollias G., and van De Loo F. A., 1999, "Role of tumour necrosis factor alpha in experimental arthritis: separate activity of interleukin 1beta in chronicity and cartilage destruction", Ann. Rheum. Dis., 58 Suppl 1, I40-8 [PubMed].

Kollias G., Douni E., Kassiotis G., Kontoyiannis D., 1999, "The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease", Ann. Rheum. Dis., 58 Suppl 1, I32-9 [PubMed].

Kollias G., Douni E., Kassiotis G., Kontoyiannis D., 1999, "On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease", Immunol. Rev., 169, 175-194 [PubMed].

Glosli H., Veiby O. P., Fjerdingstad H., Mehlum A., Probert L., Kollias G., Gjernes E., Prydz H., 1999, "Effects of hTNFalpha expression in T cells on haematopoiesis in transgenic mice", Eur. J. Haematol., 63, 50-60 [PubMed].

Moore R. J., Owens D. M., Stamp G., Arnott C., Burke F., East N., Holdsworth H., Turner L., Rollins B., Pasparakis M., Kollias G., Balkwill F., 1999, "Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis", Nat. Med., 5, 828-831 [PubMed].

Zhang Y., Pasparakis M., Kollias G., Simons M., 1999, "Myocyte-dependent regulation of endothelial cell syndecan-4 expression. Role of TNF-alpha", J. Biol. Chem., 274, 14786-14790 [PubMed].

Kontoyiannis D., Pasparakis M., Pizarro T. T., Cominelli F., Kollias G., 1999, "Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU- rich elements: implications for joint and gut-associated immunopathologies", Immunity, 10, 387-398 [PubMed].

Kassiotis G., Bauer J., Akassoglou K., Lassmann H., Kollias G., Probert L., 1999, "A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice", Eur. J. Immunol., 29, 912-917 [PubMed].

Kassiotis G., Bauer J., Akassoglou K., Lassmann H., Kollias G., Probert L., 1999, "TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis", Eur. J. Immunol., 29:1, 774-780 [PubMed].

Neurath M. F., Hildner K., Becker C., Schlaak J. F., Barbulescu K., Germann T., Schmitt E., Schirmacher P., Haralambous S., Pasparakis M., Meyer Z. B. K., Kollias G., Marker-Hermann E., 1999, "Methotrexate specifically modulates cytokine production by T cells and macrophages in murine collagen-induced arthritis (CIA): a mechanism for methotrexate-mediated immunosuppression", Clin. Exp. Immunol., 115, 42-55 [PubMed].

Plows D., Kontogeorgos G., Kollias G., 1999, "Mice lacking mature T and B lymphocytes develop arthritic lesions after immunization with type II collagen", J. Immunol., 162, 1018-1023 [PubMed].

1998

Adorini L., Bonneville M., Kollias G., 1998, "Pathogenic and protective T-cell responses in autoimmune diseases", Res. Immunol., 149, 873-875 [PubMed].

Tselios T., Probert L., Kollias G., Matsoukas E., Roumelioti P., Alexopoulos K., Moore G. J., Matsoukas J., 1998, "Design and synthesis of small semi-mimetic peptides with immunomodulatory activity based on myelin basic protein (MBP)", Amino. Acids., 14, 333-341 [PubMed].

Maurer M., Echtenacher B., Hultner L., Kollias G., Mannel D. N., Langley K. E., Galli S. J., 1998, "The c-kit ligand, stem cell factor, can enhance innate immunity through effects on mast cells", J. Exp. Med., 188, 2343-2348 [PubMed].

Douni E., Kollias G., 1998, "A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF- R", J. Exp. Med., 188, 1343-1352 [PubMed].

Akassoglou K., Bauer J., Kassiotis G., Pasparakis M., Lassmann H., Kollias G., Probert L., 1998, "Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy", Am. J. Pathol., 153, 801-813 [PubMed].

Alexopoulou L., Pasparakis M., Kollias G., 1998, "Complementation of lymphotoxin alpha knockout mice with tumor necrosis factor-expressing transgenes rectifies defective splenic structure and function", J. Exp. Med., 188, 745-754 [PubMed].

Fiore M., Alleva E., Probert L., Kollias G., Angelucci F., Aloe L., 1998, "Exploratory and displacement behavior in transgenic mice expressing high levels of brain TNF-alpha", Physiol. Behav., 63, 571-576 [PubMed].

Bessis N., Chiocchia G., Kollias G., Minty A., Fournier C., Fradelizi D., Boissier M. C., 1998, "Modulation of proinflammatory cytokine production in tumour necrosis factor-alpha (TNF-alpha)-transgenic mice by treatment with cells engineered to secrete IL-4, IL-10 or IL-13", Clin. Exp. Immunol., 111, 391-396 [PubMed].

Alonzi T., Fattori E., Lazzaro D., Costa P., Probert L., Kollias G., De Benedetti F., Poli V., Ciliberto G., 1998, "Interleukin 6 is required for the development of collagen-induced arthritis", J. Exp. Med., 187, 461-468 [PubMed].

1997

Kusters S., Tiegs G., Alexopoulou L., Pasparakis M., Douni E., Kunstle G., Bluethmann H., Wendel A., Pfizenmaier K., Kollias G., Grell M., 1997, "In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis", Eur. J. Immunol., 27, 2870-2875 [PubMed].

Alexopoulou L., Pasparakis M., Kollias G., 1997, "A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling", Eur. J. Immunol., 27, 2588-2592 [PubMed].

Plumier J. C., Krueger A. M., Currie R. W., Kontoyiannis D., Kollias G., Pagoulatos G. N., 1997, "Transgenic mice expressing the human inducible Hsp70 have hippocampal neurons resistant to ischemic injury", Cell Stress Chaperones, 2, 162-167 [PubMed].

Butler D. M., Malfait A. M., Mason L. J., Warden P. J., Kollias G., Maini R. N., Feldmann M., Brennan F. M., 1997, "DBA/1 mice expressing the human TNF-alpha transgene develop a severe, erosive arthritis: characterization of the cytokine cascade and cellular composition", J. Immunol., 159, 2867-2876 [PubMed].

Ventre J., Doebber T., Wu M., MacNaul K., Stevens K., Pasparakis M., Kollias G., Moller D. E., 1997, "Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese mice", Diabetes, 46, 1526-1531 [PubMed].

Neurath M. F., Fuss I., Pasparakis M., Alexopoulou L., Haralambous S., Meyer Z. B. K., Strober W., Kollias G., 1997, "Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice", Eur. J. Immunol., 27, 1743-1750 [PubMed].

Pasparakis M., Alexopoulou L., Grell M., Pfizenmaier K., Bluethmann H., Kollias G., 1997, "Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor", Proc. Natl. Acad. Sci. U.S.A., 94, 6319-6323 [PubMed].

Cope A. P., Liblau R. S., Yang X. D., Congia M., Laudanna C., Schreiber R. D., Probert L., Kollias G., McDevitt H. O., 1997, "Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling", J. Exp. Med., 185, 1573-1584 [PubMed].

Probert L., Akassoglou K., Kassiotis G., Pasparakis M., Alexopoulou L., Kollias G., 1997, "TNF-alpha transgenic and knockout models of CNS inflammation and degeneration", J. Neuroimmunol., 72, 137-141 [PubMed].

Akassoglou K., Probert L., Kontogeorgos G., Kollias G., 1997, "Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice", J. Immunol., 158, 438-445 [PubMed].

1996

Pasparakis M., Alexopoulou L., Douni E., Kollias G., 1996, "Tumour necrosis factors in immune regulation: everything that's interesting is...new!", Cytokine Growth Factor Rev., 7, 223-229 [PubMed].

Pasparakis M., Alexopoulou L., Episkopou V., Kollias G., 1996, "Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response", J. Exp. Med., 184, 1397-1411 [PubMed].

Fiore M., Probert L., Kollias G., Akassoglou K., Alleva E., Aloe L., 1996, "Neurobehavioral alterations in developing transgenic mice expressing TNF-alpha in the brain", Brain Behav. Immun., 10, 126-138 [PubMed].

Georgopoulos S., Plows D., Kollias G., 1996, "Transmembrane TNF is sufficient to induce localized tissue toxicity and chronic inflammatory arthritis in transgenic mice", J. Inflamm., 46, 86-97 [PubMed].

Probert L., Akassoglou K., Alexopoulou L., Douni E., Haralambous S., Hill S., Kassiotis G., Kontoyiannis D., Pasparakis M., Plows D., Kollias G., 1996, "Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice", J. Leukoc. Biol., 59, 518-525 [PubMed].

1995

Douni E., Akassoglou K., Alexopoulou L., Georgopoulos S., Haralambous S., Hill S., Kassiotis G., Kontoyiannis D., Pasparakis M., Plows D., Probert L., Kollias G., 1995, "Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis", J. Inflamm., 47, 27-38 [PubMed].

Grell M., Douni E., Wajant H., Lohden M., Clauss M., Maxeiner B., Georgopoulos S., Lesslauer W., Kollias G., Pfizenmaier K., 1995, "The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor", Cell, 83, 793-802 [PubMed].

Plumier J. C., Ross B. M., Currie R. W., Angelidis C. E., Kazlaris H., Kollias G., Pagoulatos G. N., 1995, "Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery", J. Clin. Invest., 95, 1854-1860 [PubMed].

Probert L., Plows D., Kontogeorgos G., Kollias G., 1995, "The type I interleukin-1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF-transgenic mice", Eur. J. Immunol., 25, 1794-1797 [PubMed].

Aloe L., Probert L., Kollias G., Micera A., Tirassa P., 1995, "Effect of NGF antibodies on mast cell distribution, histamine and substance P levels in the knee joint of TNF-arthritic transgenic mice", Rheumatol. Int., 14, 249-252 [PubMed].

Siegel S. A., Shealy D. J., Nakada M. T., Le J., Woulfe D. S., Probert L., Kollias G., Ghrayeb J., Vilcek J., Daddona P. E., 1995, "The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo", Cytokine, 7, 15-25 [PubMed].

Probert L., Akassoglou K., Pasparakis M., Kontogeorgos G., Kollias G., 1995, "Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha", Proc. Natl. Acad. Sci. U.S.A., 92, 11294-11298 [PubMed].

1994

Taverne J., Sheikh N., de Souza J. B., Playfair J. H., Probert L., Kollias G., 1994, "Anaemia and resistance to malaria in transgenic mice expressing human tumour necrosis factor", Immunology, 82, 397-403 [PubMed].

1993

Grigoreas C., Pappas D., Galatas I. D., Kollias G., Papadimos S., Papadakis P., 1993, "Serum total IgE levels in a representative sample of a Greek population. I. Correlation with age, sex, and skin reactivity to common aeroallergens", Allergy, 48 (3), 142-146 [PubMed].

Probert L., Keffer J., Corbella P., Cazlaris H., Patsavoudi E., Stephens S., Kaslaris E., Kioussis D., Kollias G., 1993, "Wasting, ischemia, and lymphoid abnormalities in mice expressing T cell- targeted human tumor necrosis factor transgenes", J. Immunol., 151, 1894-1906 [PubMed].

Kollias G., 1993, "Tumour necrosis factor: a specific trigger in arthritis", Res. Immunol., 144, 342-347 [PubMed].

Aloe L., Probert L., Kollias G., Bracci-Laudiero L., Spillantini M. G., Levi-Montalcini R., 1993, "The synovium of transgenic arthritic mice expressing human tumor necrosis factor contains a high level of nerve growth factor", Growth Factors, 9, 149-155 [PubMed].

Aloe L., Probert L., Kollias G., Bracci-Laudiero L., Micera A., Mollinari C., Levi-Montalcini R., 1993, "Level of nerve growth factor and distribution of mast cells in the synovium of tumour necrosis factor transgenic arthritic mice", Int. J. Tissue React., 15, 139-143 [PubMed].

1991

Keffer J., Probert L., Cazlaris H., Georgopoulos S., Kaslaris E., Kioussis D., Kollias G., 1991, "Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis", EMBO J., 10, 4025-4031 [PubMed].

Dillon N., Kollias G., Grosveld F., Williams J. G., 1991, "Expression of adult and tadpole specific globin genes from Xenopus laevis in transgenic mice", Nucleic. Acids. Res., 19, 6227-6230 [PubMed].

1988

Grosveld F., Kollias G., 1988, "Ectopic expression of Thy-1 in the kidneys of transgenic mice induces functional and proliferative abnormalities", Cell, 54, 920 [PubMed].

1987

Grosveld F., van Assendelft G. B., Greaves D. R., Kollias G., 1987, "Position-independent, high-level expression of the human beta-globin gene in transgenic mice", Cell, 51, 975-985 [PubMed].

Grosveld F., Antoniou M., van Assendelft G. B., de Boer E., Hurst J., Kollias G., MacFarlane F., Wrighton N., 1987, "The regulation of expression of human beta-globin genes", Prog. Clin. Biol. Res., 251, 133-144 [PubMed].

Kollias G., Hurst J., deBoer E., Grosveld F., 1987, "The human beta-globin gene contains a downstream developmental specific enhancer", Nucleic. Acids. Res., 15, 5739-5747 [PubMed].

Kollias G., Evans D. J., Ritter M., Beech J., Morris R., Grosveld F., 1987, "Ectopic expression of Thy-1 in the kidneys of transgenic mice induces functional and proliferative abnormalities", Cell, 51, 21-31 [PubMed].

Kollias G., Spanopoulou E., Grosveld F., Ritter M., Beech J., Morris R., 1987, "Differential regulation of a Thy-1 gene in transgenic mice", Proc. Natl. Acad. Sci. U.S.A., 84, 1492-1496 [PubMed].

1986

Kollias G., Wrighton N., Hurst J., Grosveld F., 1986, "Regulated expression of human A gamma-, beta-, and hybrid gamma beta- globin genes in transgenic mice: manipulation of the developmental expression patterns", Cell, 46, 89-94 [PubMed].

Kolsto A. B., Kollias G., Giguere V., Isobe K. I., Prydz H., Grosveld F., 1986, "The maintenance of methylation-free islands in transgenic mice", Nucleic. Acids. Res., 14, 9667-9678 [PubMed].

Isobe K., Kollias G., Kolsto A. B., Grosveld F., 1986, "T cell independent Thy-1 allo-antibody response with the use of transgenic mice", J. Immunol., 137, 2089-2092 [PubMed].

1985

Kollias G., Sekeris C. E., Grosveld F. G., 1985, "Alpha-amanitin insensitive transcription of the human epsilon-globin gene", Nucleic. Acids. Res., 13, 7993-8005 [PubMed].