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Eleni Douni's research group

Conference Presentations

Conference Talks:

Niti A, Dacquin R, Rinotas V, Jurdic P, Douni E. (2010). A novel genetic model of osteoporosis by overexpression of human RANKL in transgenic mice. 24th International Mammalian Genome Conference. 17-21 October, Heraklion. (Research poster AWARD)

Ioakeimidis F, Rinotas V, Makrinou E, Kollias G, Douni E. (2010). A forward genetics approach identifies a novel member of the DnaJC family that causes neuromuscular disease in mice. 24th International Mammalian Genome Conference. 17-21 October, Heraklion. (Travel scholarship).

Douni E. (2010). Genetic Standardization. 4th International Course on Laboratory Animal Science. 4-15 October, Athens. (Invited Talk)

Douni E. (2010). Forward Genetics. 4th International Course on Laboratory Animal Science. 4-15 October, Athens. (Invited Talk)

Ioakeimidis F, Rinotas V, Makrinou E, Kollias G, and Douni E. (2010). Identification of a novel member of the DnaJC family that causes neuromuscular disease in mice. Neuroscience days of the Hellenic Society for Neuroscience. 1-2 October, Athens.

Douni E. (2010). Transgenic mice overexpressing RANKL as a model of osteoporosis. 18th Hellenic Conference of Hellenic Society of Studying Bone Metabolism. Round table: Experimental models of Osteoporosis. 14-16 May, Athens. (Invited Talk) 

Douni E. (2010). The role of RANKL in osteoimmunology and development of therapies in transgenic mice. Psoriasis and Arthritides, update and new perspectives. 23-24 January, Heraklion.  (Invited Talk)

Douni E. (2009). Functional Genetics in animal models. 1rst Hellenic Conference of Agricultural Biotechnology, 16-18 October, Athens. (Invited Talk)

Douni E. (2009). Forward and Reverse Genetics. Workshop on Mouse Immune Phenotyping. 6-8 October, Athens. (Invited Talk)

Douni E. (2009). Genetic Standardization. 3rd International Course on Laboratory Animal Science. 21 September-2 October, Athens. (Invited Talk)

Douni E. (2009). Forward Genetics. 3rd International Course on Laboratory Animal Science. 21 September-2 October, Athens. (Invited Talk)

Douni E. (2009). Forward genetics: a tool for the discovery of novel disease targets in Immunology. 2nd Immunology Summer School & Conference, 31 August-4 September, Kefalonia.  (Invited Talk)

Douni E. (2009). Genotyping core. 5th MUGEN Annual & Review Meeting. 26-28 January, Athens.

Douni E. (2008). Genetically modified animal models in Osteoimmunology. 2nd Hellenic Seminar of Experimental Biomedical Research. 20-22 November, Athens. (Invited Talk)

Douni E. (2008). Functional genomics to understand pathophysiology in animal models. 27th Congress of the International Academy of Pathology. 12-17 October, Athens. (Invited Talk)

Douni E. (2008). The osteoblast, the osteoclast and osteoporosis. 64th Hellenic Orthopedic Conference. Round table: Osteoporosis today. 8-11 October, Athens. (Invited Talk)

Douni E. (2008). Forward Genetics. 2nd International Course on Laboratory Animal Science. 22 September-3 October, Athens. (Invited Talk)

Douni E, Makrinou E, Kollias G. (2008). Identification of a novel loss-of-function missense mutation in the RANKL gene that causes osteopetrosis in mice. 35th European Symposium on calcified tissues. 24-28 May, Barcelona Spain. Published in Calcified Tissue International vol 82, suppl. Abstract Mo-OP35 p.S57.

Douni E. (2008). Functional Genomics for the understanding of pathophysiology in animal models. 14th Scientific Conference of Greek Medical School Students. 9-11 May, Athens. (Invited Talk)

Douni E. (2008). Genotyping core. 4th MUGEN Annual & Review Meeting. 28-30 January, Athens.

Douni E. (2008). Chronic inflammatory disease mechanisms and development of therapies. 28th European Section Meeting of the International Society for Heart Research. 28-31 May, Athens. (Invited Talk)

Douni E. (2007). Molecular Biology and genetically modified animal models. 1rst  Hellenic Seminar of Experimental Biomedical Research. 11-14 December, Athens. (Invited Talk)

Douni E, Makrinou E, Kollias G. (2007). Identification of a novel loss-of-function missense mutation in the RANKL gene using ENU mutagenesis. 21rst International Mouse Genome Conference, 28 October-1 November, Kyoto Japan. Abstract No P108 p.144.

Douni E. (2007). ENU Mutagenesis. 1rst International Course on Laboratory Animal Science. 24 September-5 October, Athens. (Invited Talk)

Douni E. (2006). Novel approaches studying inflammation. 19th Hellenic Rheumatology Conference., 29Nov.-2 Dec., Athens. (Invited Talk)

Douni E. (2006). Identification of  disease targets using random ENU mutagenesis in animal models. 3rd International Biotechnological Conference. 5-7 October, Athens. (Invited Talk)

Douni E, Armaka M, Makrinou E, and Kollias G. (2006). Functional genetic and genomic analysis of modeled arthritis and other bone diseases. 16th European Congress of Immunology. September 6-9, Paris. Abstract No SC55-770. (Invited Talk)

Douni E, Armaka M, Makrinou E, Kollias G. (2006). Functional genetic and genomic analysis of modeled arthritis and osteoclastogenesis. 1rst International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, May 28-June 2, Crete. Aegean Conference Series vol.22, Abstract No5. (Invited Talk)

Douni E. (2006). Random ENU Mutagenesis. MUGEN Transgenesis Gene Targeted Mutagenesis Course. April 10-13, Athens. (Invited Talk)

Douni E, Makrinou E, Mermelekas G, Giannakas N, Kollias G. (2005). A sensitized ENU mutagenesis screen for genetic modifiers of Rheumatoid Arthritis and Inflammatory Bowel Disease. 19th International Mouse Genome Conference. 4-8 November, Strasbourg, France. Abstract No O-15, p.58.

Douni E. (2005). Anti-TNF and anti-IL-1 therapies: from mouse to human. Hellenic Conference of Pathology. 11-14 October, Athens. (Invited Talk)

Douni E, Makrinou E, Kollias G. (2005). Genome wide analysis of sensitized ENU mutagenesis screens in animal models for arthritis and IBD, as a tool for drug target discovery. Mutation detection workshop. 31 May-4 June, Santorini.

Douni E. (2004). Random mutagenesis in animal models of human immunological diseases for the discovery of new therapeutic targets. Hellenic Conference of Immunology. 8-11 December, Thessaloniki. (Invited Talk)

Douni E. (2004). Transgenic and knockout systems in Immunology. Hellenic Society of Immunology. Seminar in Immunology 20th cycle. 25 January, Athens. (Invited Talk)

Douni E. (2003). Experimental animal models in sepsis. Preconference seminar of sepsis during the 9th Hellenic Conference of Intense Therapy. 16 October, Athens. (Invited Talk)

Douni E, Sekara E, Kamber M, Mantellou M, Kontoyiannis D, Kollias G. (2003). Random mutagenesis in animal models of chronic inflammatory diseases as a tool for drug target discovery. 1st  Turkish-Greek Reumatology Days, 23-24 May, Marmaris, Turkey.

Douni E, Mantellou M, Sekara E, Kollias G. (2002). A sensitized ENU mutagenesis screen for the discovery of disease modifier genes in a murine model of TNF-mediated Inflammatory Arthritis and Inflammatory Bowel Pathology. 15th IIGB Meeting “From genome sequence to functional analysis and medical applications”. 12-15 October. Capri, Italy. Abstract page 25.

Douni Ε, Kollias G. (2000). A critical role for T lymphocytes in the multi-organ inflammatory pathology induced by chronic overexpression of the p75TNF-R in transgenic mice. 8th International TNF Congress, 14-18 May Trondheim, Norway. Published in Scandinavian Journal of Immunology, Vol 51 Abstract No 5.22, p.84.


Posters:

Niti A, Dacquin R, Rinotas V, Jurdic P, Douni E. (2010). A novel genetic model of osteoporosis by overexpression of human RANKL in transgenic mice. 24th International Mammalian Genome Conference. 17-21 October, Heraklion.

Karakostas A, Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2010). Identification of a novel SLC25 member that causes autosomal recessive ataxia in ENU-mutageneized mice. 24th International Mammalian Genome Conference. 17-21 October, Heraklion.

Ioakeimidis F, Rinotas V, Makrinou E, Kollias G, Douni E. (2010). A forward genetics approach identifies a novel member of the DnaJC family that causes neuromuscular disease in mice. 24th International Mammalian Genome Conference. 17-21 October, Heraklion.

Karakostas A, Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2010). Identification of a novel SLC25 member that causes autosomal recessive ataxia in ENU-mutagenized mice. Neuroscience days of the Hellenic Society for Neuroscience. 1-2 October, Athens.

Niti A, Dacquin R, Rinotas V, Jurdic P, Douni E. (2010). Generation and analysis of a novel genetic model of osteoporosis:Human RANKL-expressing transgenic mice. 3rd International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, June 20-25, Santorini. Aegean Conference Series vol.49, Abstract No 65.

Douni E, Aidinis V, Kontoyiannis D, Graf D, Kollias G. (2010). Secondary immunological phenotyping using animal models for human inflammatory and autoimmune diseases. EUMODIC Annual Meeting, March 25-26, Brussels.

Karakostas A, Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2010). Identification and characterization of a novel SLC25 member that causes autosomal recessive ataxia in mice. EUMODIC Annual Meeting, March 25-26, Brussels.

Niti A, Rinotas V, Douni E. (2009). A novel genetic model of osteoporosis in transgenic mice expressing human RANKL. 2nd MUGEN Conference, 8-10 October, Athens.

Ioakeimidis F, Karakostas A, Rinotas V, Makrinou E, Kollias G, Douni E. (2009). A novel ENU-induced mouse model of autosomal recessive neuromuscular disease and lymphoid abnormalities. 2nd MUGEN Conference, 8-10 October, Athens.

Karakostas A, Ioakeimidis F, Rinotas V, Kollias G, Douni E. (2009). Identification of a new SLC25 member that causes autosomal recessive ataxia in ENU-mutagenized mice. 2nd MUGEN Conference, 8-10 October, Athens.

Niti A, Rinotas V, Douni E. (2009). A novel humanized RANKL transgenic mouse model of osteoporosis. 36th European Symposium on calcified tissues, 23-27 May, Vienna. Bone vol44, no2 p.S423.

Ioakeimidis F, Rinotas V, Makrinou E, Kollias G, Douni E. (2009). Characterization of a novel mouse model of autosomal recessive neuromuscular disease and lymphoid hypoplasia generated by ENU mutagenesis. 4th ENII-MUGEN Immunology Summer School, 17-24 May, Capo Caccia, Sardinia.

Douni E, Aidinis V, Kontoyiannis D, Graf D, Kollias G. (2009). Secondary immunological phenotyping using animal models for human inflammatory and autoimmune diseases: the MUGEN approach. EUMODIC Annual Meeting, March 2-4, Athens, Greece.

Douni E, Makrinou E, Zwerina J, Penninger JM, Schett G Kollias G. (2008). Identification and characterization of a novel loss-of-function missense mutation in the RANKL gene that causes osteopetrosis in mice. 2nd International Conference on Osteoimmunology: Interactions of the immune and skeletal systems. Aegean Conferences, June 8-13, Rhodes. Aegean Conference Series vol.35, Abstract No 62.

Douni E, Makrinou E, Mermelekas G, Giannakas N, Kollias G. (2007). Identification of genetic modifiers using random mutagenesis in Rheumatoid Arthritis and Inflammatory Bowel Disease. 21rst International Mouse Genome Conference, 28 October-1 November, Kyoto Japan. Abstract No P109 p.144.

Beirnaert E, Lauwereys M, De Haard H, Casteels P, Jonckheere H, Spinelli S, Cambillau C, Douni E, Kollias G, Hoogenboom H, Dreier T. (2006). Superior efficacy of a format engineered anti-human TNFa nanobody in a transgenic mouse model (Tg197) of polyarthritis.16th European Congress of Immunology. September 6-9, Paris. Abstract No WD60-339.

Kranidioti K, Alexopoulou L, Kranidioti K, Xanthoulea S, Denis M, Kotanidou A, Douni E, Blackshear PJ, Kontoyiannis DL, Kollias G. (2006). Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity. 1rst International MUGEN Conference on animal models for human immunological disease.  September 10-13, Athens. Abstract No 27.

Douni E, Makrinou E, Giannakas N, Alexakos G, Kollias G. (2006). A sensitized ENU mutagenesis screen for genetic modifiers of Rheumatoid Arthritis and Inflammatory Bowel Disease. 1rst International MUGEN Conference on animal models for human immunological disease.  September 10-13, Athens. Abstract No 44.

Sotsios Y, Douni E, Kollias G. (2006). TNF-driven animal models of inflammatory disease: effective tools for pre-clinical in vivo evaluation of pharmaceuticals. 1rst International MUGEN Conference on animal models for human immunological diseaseSeptember 10-13, Athens. Abstract No 52.

Douni E, Sekara E, Kamber M, Kontoyiannis D, Kollias G. (2004). Sensitized ENU mutagenesis screen in animal models of chronic inflammatory diseases. Eumorphia annual meeting. 5-7 October, London.

Faggioni R, Babcook J, Douni E, Kang J, Schneider A, Manchulenko K, Rathanaswami P, Kollias G (2004). ABX10131: a fully human anti-human TNF mAb generated using XenoMouse® and XenoMax™ technologies. ICS and ICICR 5th Joint International Meeting, October.

Douni E, Sekara E, Kamber M, Mantellou M, Kontoyiannis D, Kollias G. (2003). A sensitized ENU mutagenesis screen in animal models of chronic inflammatory diseases as a tool for drug target discovery. 17th International Mouse Genome Conference, 9-12 November, Braunschweig, Germany. Abstract No 31.

 

Old conferences:

Kollias G, Douni E, Kontoyiannis D. (1998). New insights into the regulation of biosynthesis and function of TNF and its receptors. 2nd joint meeting of the International Cytokine Society and the International Society for Interferon and Cytokine Research, 25-30 October, Jerusalem. Published in European Cytokine Network Vol 9, Abstract No 526, p. 342.

Akassoglou K, Douni E, Bauer J, Lassmann H, Kollias G, Probert L. (1998). Transmembrane TNF signaling through p75TNFR induces inflammatory ischaemia in the CNS of transgenic mice. 7th International TNF Congress, 17-21 May, Cape Cod USA. Published in Journal of Interferon & Cytokine Research Vol 18, Abstract No  5.02, p. A-87.

Tiegs G, Kusters S, Wolf D, Hallmann R, Alexopoulou L, Pasparakis M, Douni E, Kunstle G, Bluethmann H, Pfizenmaier K, Kollias G, Grell M. (1998). Both TNF receptors and transmembrane TNF mediate experimental hepatitis in mice. 7th International TNF Congress, 17-21 May, Cape Cod USA. Published in Journal of Interferon & Cytokine Research Vol 18, Abstract No  5.52, p. A-112.

Douni E, Kollias G. (1998). Sustained overproduction of p75TNF-R induces a lethal multi-organ inflammatory disease in the absence of TNF, LTα, or TNF receptors. 7th International TNF Congress, 17-21 May, Cape Cod USA. Published in Journal of Interferon & Cytokine Research Vol 18, Abstract No  1.10, p. A-19.

Kollias G, Akassoglou K, Alexopoulou L, Douni E, Haralambous S, Hill S, Kassiotis G, Pasparakis M, Plows D, Probert L. (1997). Transgenic animals as a mean to understanding diseases. EULAR`97, 19-22 November, Vienna, Austria.

Kontoyianni D, Alexopoulou L, Douni E, Haralambous S, Pasparakis M, Plows D,  Kollias G. (1997). Transgenic and knockout mice in arthritis models. 4th International Symposium on the Immunotherapy of the Rheumatic Diseases, 21-25 May, Limassol, Cyprus.

Douni E, Kollias G. (1997). A role for the p75 Tumour Necrosis Factor receptor in lymphocyte development and systemic inflammation. 13th European Immunology Meeting, 22-25 June, Amsterdam. Published in Immunology letters Vol 56, Abstract No P.2.0203, p. 93.

Pasparakis M, Alexopoulou L, Douni E, Kollias G. (1997). Role of the TNF/LT/receptor development and function of secondary lymhoid organs. 13th European Immunology Meeting, 22-25 June, Amsterdam. Published in Immunology letters Vol 56, Abstract No P.2.06.03,  p. 394.

Douni E, Grell M, Pfizenmaier K, Kollias G. (1996). Development of local lymphoid-like follicles at sites of TNF overexpression. 6th International TNF Congress, 8-12 May, Rhodes, Hellas. Published in European Cytokine Network Vol 7, Abstract No. 10, p. 164.

Douni E, Grell M, Pfizenmaier K, Kollias G. (1995). Transgenic analyses of human p75 TNF receptor function. The International Cytokine Society, 3rd Annual Conference, 12-15 September, Harrogate U.K.

Karidis I, Douni E, Mosxogianni C, Karagiorga M, Kollias G, Haziliami A, Katsantonis A, Tolis G. (1995). Studying the Growth Hormone axon on children of short and normal height suffering from Mediterranean Anemia. 22nd Hellenic Endocrinological Conference, 6-9 April, Rio Patra.   

Douni E, Grell M, Pfizenmaier K, Kollias G. (1994). Probing the function of the human p75 TNF receptor by its targeted expression in T cells of transgenic mice. 5th International TNF Congress, 31 May -3 June, Asilomar, California U.S.A. Published in European Cytokine Network Vol 5, Abstract No. 80, p. 127.

Kollias G, Alexopoulou L, Douni E, Georgopoulos S, Pasparakis M, Probert L. (1993). Modeling arthritis in transgenic mice. 6th French Congress of Rheumatology, 26 November, Paris.

Kollias G, Alexopoulou L, Douni E, Georgopoulos S, Harami P, Pasparakis M,  Probert L. (1993). Modeling arthritis or a sepsis-like syndrome in TNF transgenic mice. Mouse Molecular Genetics, 18-22 August, EMBL Heidelberg.

Kollias G, Douni E, Georgopoulos S, Pasparakis M, Probert L. (1993). Analysis of TNF Biology in transgenic mice. Molecular Mechanisms in Rheumatoid Arthritis and Related Disease, 31 January-7 February, Keystone Colorado.

Kollias G, Douni E, Georgopoulos S, Harami P, Pasparakis M, Probert L. (1993). Modeling arthritis in  transgenic mice. XIII European Workshop for Rheumatology Research, 28-30 January, Brighton.

Kollias G, Dodou E, Douni E, Georgopoulos S, Harami P, Pasparakis M, Probert L. (1992). Transgenic approaches in the study of TNF Biology. The Cytokine System in Health and Disease, 8th Annual Sympossium on Biotechnology, 10-11 December, London.

Probert L, Dodou E, Douni E, Georgopoulos S, Pasparakis M, Kollias G. (1992). Transgenic models of Human Tumour Necrosis Factor mediated disease. Mouse Molecular Genetics, 26-30 August, Cold Spring Harbour.