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Eleni Douni's research group
Conference Presentations
Conference Talks:
Niti A, Dacquin R, Rinotas V, Jurdic P, Douni E.
(2010). A novel genetic model of osteoporosis by overexpression
of human RANKL in transgenic mice. 24th International Mammalian
Genome Conference. 17-21 October, Heraklion. (Research poster AWARD)
Ioakeimidis F, Rinotas V, Makrinou E, Kollias G, Douni E.
(2010). A forward genetics approach identifies a novel member of
the DnaJC family that causes neuromuscular disease in mice. 24th
International Mammalian Genome Conference. 17-21 October, Heraklion.
(Travel scholarship).
Douni E. (2010). Genetic Standardization. 4th
International Course on Laboratory Animal Science. 4-15 October,
Athens. (Invited Talk)
Douni E. (2010). Forward Genetics. 4th International
Course on Laboratory Animal Science. 4-15 October, Athens. (Invited
Talk)
Ioakeimidis F, Rinotas V, Makrinou E, Kollias G, and Douni E.
(2010). Identification of a novel member of the DnaJC family that
causes neuromuscular disease in mice. Neuroscience days of the
Hellenic Society for Neuroscience. 1-2 October, Athens.
Douni E.
(2010). Transgenic mice overexpressing RANKL as a model of
osteoporosis. 18th Hellenic Conference of Hellenic
Society of Studying Bone Metabolism. Round table:
Experimental models of Osteoporosis. 14-16 May, Athens.
(Invited Talk)
Douni E.
(2010). The role of RANKL in osteoimmunology and development of
therapies in transgenic mice. Psoriasis and Arthritides,
update and new perspectives. 23-24 January, Heraklion. (Invited
Talk)
Douni E.
(2009). Functional Genetics in animal models. 1rst
Hellenic Conference of Agricultural Biotechnology, 16-18 October,
Athens. (Invited Talk)
Douni E.
(2009). Forward and Reverse Genetics. Workshop on
Mouse Immune Phenotyping. 6-8 October, Athens.
(Invited Talk)
Douni E.
(2009). Genetic Standardization. 3rd
International Course on Laboratory Animal Science. 21
September-2 October, Athens.
(Invited Talk)
Douni E.
(2009). Forward Genetics. 3rd International
Course on Laboratory Animal Science. 21 September-2
October, Athens. (Invited
Talk)
Douni E.
(2009). Forward genetics: a tool for the discovery of novel
disease targets in Immunology. 2nd Immunology
Summer School & Conference, 31 August-4 September, Kefalonia.
(Invited Talk)
Douni E.
(2009). Genotyping core. 5th MUGEN Annual & Review
Meeting. 26-28 January, Athens.
Douni E.
(2008). Genetically modified animal models in Osteoimmunology.
2nd Hellenic Seminar of Experimental Biomedical
Research. 20-22 November, Athens. (Invited Talk)
Douni E.
(2008). Functional genomics to understand pathophysiology in
animal models. 27th Congress of the International
Academy of Pathology. 12-17 October, Athens. (Invited Talk)
Douni E.
(2008). The osteoblast, the osteoclast and osteoporosis.
64th Hellenic Orthopedic Conference. Round table:
Osteoporosis today. 8-11 October, Athens. (Invited Talk)
Douni E.
(2008). Forward Genetics. 2nd International
Course on Laboratory Animal Science. 22 September-3
October, Athens. (Invited
Talk)
Douni E,
Makrinou E, Kollias G. (2008).
Identification of a novel loss-of-function missense mutation in the
RANKL gene that causes osteopetrosis in mice.
35th European Symposium on calcified tissues.
24-28 May, Barcelona Spain. Published in Calcified Tissue
International vol 82, suppl. Abstract Mo-OP35 p.S57.
Douni E.
(2008). Functional Genomics for the understanding of
pathophysiology in animal models. 14th Scientific
Conference of Greek Medical School Students. 9-11 May, Athens.
(Invited Talk)
Douni E.
(2008). Genotyping core. 4th MUGEN Annual & Review
Meeting. 28-30 January, Athens.
Douni E.
(2008). Chronic inflammatory disease mechanisms and development
of therapies. 28th European Section Meeting of the
International Society for Heart Research. 28-31 May,
Athens. (Invited Talk)
Douni E.
(2007). Molecular Biology and genetically modified animal models.
1rst Hellenic Seminar of
Experimental Biomedical Research. 11-14 December, Athens.
(Invited Talk)
Douni E,
Makrinou E, Kollias G. (2007).
Identification of a novel loss-of-function missense mutation in the
RANKL gene using ENU mutagenesis.
21rst International Mouse Genome Conference, 28
October-1 November, Kyoto Japan. Abstract No P108 p.144.
Douni E.
(2007). ENU Mutagenesis. 1rst International
Course on Laboratory Animal Science. 24 September-5 October,
Athens. (Invited Talk)
Douni E.
(2006). Novel approaches studying inflammation. 19th
Hellenic Rheumatology Conference., 29Nov.-2 Dec., Athens.
(Invited Talk)
Douni E.
(2006). Identification of disease targets using random ENU
mutagenesis in animal models. 3rd International
Biotechnological Conference. 5-7 October, Athens. (Invited Talk)
Douni E,
Armaka M, Makrinou E, and Kollias G. (2006).
Functional genetic and genomic analysis of
modeled arthritis and other bone diseases.
16th European Congress of Immunology. September
6-9, Paris. Abstract No SC55-770. (Invited Talk)
Douni E,
Armaka M, Makrinou E, Kollias G. (2006).
Functional genetic and genomic analysis of
modeled arthritis and osteoclastogenesis.
1rst International Conference on Osteoimmunology:
Interactions of the immune and skeletal systems. Aegean
Conferences, May 28-June 2, Crete. Aegean Conference Series vol.22,
Abstract No5. (Invited Talk)
Douni E.
(2006). Random ENU Mutagenesis.
MUGEN Transgenesis Gene Targeted Mutagenesis Course. April
10-13, Athens. (Invited Talk)
Douni E,
Makrinou E, Mermelekas G, Giannakas N, Kollias G. (2005).
A sensitized ENU mutagenesis screen for genetic
modifiers of Rheumatoid Arthritis and Inflammatory Bowel Disease.
19th International Mouse Genome Conference. 4-8
November, Strasbourg, France. Abstract No O-15, p.58.
Douni E.
(2005). Anti-TNF and anti-IL-1 therapies: from mouse to human.
Hellenic Conference of Pathology. 11-14 October,
Athens. (Invited Talk)
Douni
E,
Makrinou
E, Kollias G. (2005).
Genome wide analysis of sensitized ENU mutagenesis
screens in animal models for arthritis and IBD, as a tool for drug
target discovery.
Mutation detection workshop.
31 May-4 June, Santorini.
Douni E.
(2004). Random mutagenesis in animal models of human
immunological diseases for the discovery of new therapeutic targets.
Hellenic Conference of Immunology. 8-11 December,
Thessaloniki. (Invited Talk)
Douni E.
(2004). Transgenic and knockout systems in Immunology.
Hellenic Society of Immunology. Seminar in Immunology 20th
cycle. 25 January, Athens. (Invited Talk)
Douni E.
(2003). Experimental animal models in sepsis.
Preconference seminar of sepsis during the 9th Hellenic
Conference of Intense Therapy. 16 October, Athens. (Invited
Talk)
Douni
E,
Sekara E, Kamber M, Mantellou M, Kontoyiannis D, Kollias G. (2003).
Random mutagenesis
in animal models of chronic inflammatory diseases as a tool for drug
target discovery.
1st Turkish-Greek Reumatology Days, 23-24 May, Marmaris, Turkey.
Douni E,
Mantellou M, Sekara E, Kollias G. (2002). A sensitized ENU
mutagenesis screen for the discovery of disease modifier genes in a
murine model of TNF-mediated Inflammatory Arthritis and Inflammatory
Bowel Pathology. 15th IIGB Meeting “From
genome sequence to functional analysis and medical applications”.
12-15 October. Capri, Italy. Abstract page 25.
Douni
Ε,
Kollias G. (2000). A critical role for
T lymphocytes in the multi-organ inflammatory pathology induced by
chronic overexpression of the p75TNF-R in transgenic mice.
8th International TNF Congress, 14-18 May
Trondheim, Norway. Published in
Scandinavian Journal of Immunology, Vol 51 Abstract No 5.22, p.84.
Posters:
Niti A, Dacquin R, Rinotas V, Jurdic P, Douni E.
(2010). A novel
genetic model of osteoporosis by overexpression of human RANKL in
transgenic mice.
24th International Mammalian Genome Conference. 17-21
October, Heraklion.
Karakostas A, Ioakeimidis F, Rinotas V, Kollias G,
Douni E. (2010).
Identification of a novel SLC25 member that causes autosomal
recessive ataxia in ENU-mutageneized mice. 24th
International Mammalian Genome Conference. 17-21 October,
Heraklion.
Ioakeimidis F, Rinotas V, Makrinou E, Kollias G,
Douni E. (2010).
A forward genetics approach identifies a novel
member of the DnaJC family that causes neuromuscular disease in mice.
24th International Mammalian Genome Conference.
17-21 October, Heraklion.
Karakostas A, Ioakeimidis F, Rinotas V, Kollias G,
Douni E. (2010). Identification of a novel SLC25 member that
causes autosomal recessive ataxia in ENU-mutagenized mice.
Neuroscience days of the Hellenic Society for Neuroscience. 1-2
October, Athens.
Niti
A, Dacquin R, Rinotas V, Jurdic P, Douni E. (2010).
Generation and analysis of a novel genetic model
of osteoporosis:Human RANKL-expressing transgenic mice.
3rd International Conference on Osteoimmunology:
Interactions of the immune and skeletal systems. Aegean
Conferences, June 20-25, Santorini. Aegean Conference Series vol.49,
Abstract No 65.
Douni E,
Aidinis V, Kontoyiannis D, Graf D, Kollias G. (2010).
Secondary immunological phenotyping
using animal models for human inflammatory and autoimmune diseases.
EUMODIC Annual
Meeting,
March 25-26, Brussels.
Karakostas A,
Ioakeimidis F, Rinotas V, Kollias G, Douni E.
(2010). Identification
and characterization of a novel SLC25 member that causes autosomal
recessive ataxia in mice.
EUMODIC Annual
Meeting,
March 25-26, Brussels.
Niti
A, Rinotas V, Douni E. (2009). A novel
genetic model of osteoporosis in transgenic mice expressing human
RANKL. 2nd
MUGEN Conference, 8-10 October, Athens.
Ioakeimidis F, Karakostas A, Rinotas V, Makrinou E,
Kollias G, Douni E. (2009). A novel ENU-induced mouse
model of autosomal recessive neuromuscular disease and lymphoid
abnormalities. 2nd MUGEN Conference, 8-10
October, Athens.
Karakostas A, Ioakeimidis F, Rinotas V, Kollias G,
Douni E. (2009). Identification of a new SLC25 member
that causes autosomal recessive ataxia in ENU-mutagenized mice.
2nd MUGEN Conference,
8-10 October, Athens.
Niti
A, Rinotas V, Douni E. (2009). A novel
humanized RANKL transgenic mouse model of osteoporosis.
36th European Symposium on calcified tissues,
23-27 May, Vienna. Bone vol44, no2 p.S423.
Ioakeimidis F, Rinotas V, Makrinou E, Kollias G,
Douni E. (2009).
Characterization of a novel mouse model of
autosomal recessive neuromuscular disease and lymphoid hypoplasia
generated by ENU mutagenesis.
4th ENII-MUGEN Immunology Summer School, 17-24
May, Capo Caccia, Sardinia.
Douni E,
Aidinis V, Kontoyiannis D, Graf D, Kollias G. (2009).
Secondary immunological phenotyping using animal models for human
inflammatory and autoimmune diseases: the MUGEN approach.
EUMODIC Annual Meeting,
March 2-4, Athens, Greece.
Douni E,
Makrinou E, Zwerina J, Penninger JM, Schett G Kollias G. (2008).
Identification and characterization of a novel loss-of-function
missense mutation in the RANKL gene that causes osteopetrosis in
mice. 2nd International Conference on
Osteoimmunology: Interactions of the immune and skeletal systems.
Aegean Conferences, June 8-13, Rhodes. Aegean Conference Series
vol.35, Abstract No 62.
Douni E,
Makrinou E, Mermelekas G, Giannakas N, Kollias G. (2007).
Identification of genetic modifiers using random
mutagenesis in Rheumatoid Arthritis and Inflammatory Bowel Disease.
21rst International Mouse Genome Conference, 28
October-1 November, Kyoto Japan. Abstract No P109 p.144.
Beirnaert E, Lauwereys M, De Haard H, Casteels P,
Jonckheere H, Spinelli S, Cambillau C, Douni E, Kollias G,
Hoogenboom H, Dreier T. (2006). Superior efficacy of a format
engineered anti-human TNFa nanobody in a transgenic mouse model
(Tg197) of polyarthritis.16th European Congress of Immunology.
September 6-9, Paris. Abstract No WD60-339.
Kranidioti K, Alexopoulou L, Kranidioti K, Xanthoulea
S, Denis M, Kotanidou A, Douni E, Blackshear PJ, Kontoyiannis
DL, Kollias G. (2006). Transmembrane TNF protects mutant mice
against intracellular bacterial infections, chronic inflammation and
autoimmunity. 1rst International MUGEN Conference
on animal models for human immunological disease. September
10-13, Athens. Abstract No 27.
Douni E,
Makrinou E, Giannakas N, Alexakos G, Kollias G. (2006). A
sensitized ENU mutagenesis screen for genetic modifiers of
Rheumatoid Arthritis and Inflammatory Bowel Disease. 1rst
International MUGEN Conference on animal models for human
immunological disease. September 10-13, Athens. Abstract No 44.
Sotsios Y, Douni E, Kollias G. (2006). TNF-driven
animal models of inflammatory disease: effective tools for
pre-clinical in vivo evaluation of pharmaceuticals. 1rst
International MUGEN Conference on animal models for human
immunological disease. September
10-13, Athens. Abstract No 52.
Douni
E,
Sekara E, Kamber M, Kontoyiannis D, Kollias G. (2004).
Sensitized ENU mutagenesis
screen in animal models of chronic inflammatory diseases.
Eumorphia annual meeting. 5-7 October, London.
Faggioni R, Babcook J, Douni E, Kang J, Schneider A,
Manchulenko K, Rathanaswami P, Kollias G (2004).
ABX10131: a fully human anti-human
TNF mAb generated using XenoMouse® and XenoMax™ technologies.
ICS and ICICR 5th Joint International Meeting,
October.
Douni
E,
Sekara E, Kamber M, Mantellou M, Kontoyiannis D, Kollias G. (2003).
A sensitized ENU
mutagenesis screen in animal models of chronic inflammatory diseases
as a tool for drug target discovery.
17th International Mouse Genome Conference, 9-12
November, Braunschweig, Germany. Abstract No 31.
Old conferences:
Kollias G, Douni E, Kontoyiannis D. (1998).
New insights into
the regulation of biosynthesis and function of TNF and its receptors.
2nd joint meeting of the International Cytokine
Society and the International Society for Interferon and Cytokine
Research, 25-30 October, Jerusalem. Published in European
Cytokine Network Vol 9, Abstract No 526, p. 342.
Akassoglou K, Douni E, Bauer J, Lassmann H,
Kollias G, Probert L. (1998).
Transmembrane TNF signaling through p75TNFR
induces inflammatory ischaemia in the CNS of transgenic mice.
7th International TNF Congress, 17-21 May,
Cape Cod USA. Published in Journal of
Interferon & Cytokine Research Vol 18, Abstract No 5.02, p.
A-87.
Tiegs
G, Kusters S, Wolf D, Hallmann R, Alexopoulou L, Pasparakis M,
Douni E, Kunstle G, Bluethmann H, Pfizenmaier K, Kollias G,
Grell M. (1998). Both TNF receptors and transmembrane TNF mediate
experimental hepatitis in mice. 7th International
TNF Congress, 17-21 May, Cape Cod USA.
Published in Journal of Interferon & Cytokine Research
Vol 18, Abstract No 5.52, p. A-112.
Douni E,
Kollias G. (1998). Sustained overproduction of p75TNF-R
induces a lethal multi-organ inflammatory disease in the absence of
TNF, LTα, or TNF receptors. 7th
International TNF Congress, 17-21 May, Cape Cod USA.
Published in Journal of Interferon &
Cytokine Research Vol 18, Abstract No 1.10, p. A-19.
Kollias G, Akassoglou K, Alexopoulou L, Douni E, Haralambous
S, Hill S, Kassiotis G, Pasparakis M, Plows D, Probert L. (1997).
Transgenic animals as a mean to understanding diseases.
EULAR`97, 19-22 November, Vienna, Austria.
Kontoyianni D, Alexopoulou L, Douni E,
Haralambous S, Pasparakis M, Plows D, Kollias G. (1997).
Transgenic and knockout
mice in arthritis models.
4th International Symposium on the Immunotherapy of the
Rheumatic Diseases, 21-25 May, Limassol, Cyprus.
Douni E,
Kollias G. (1997). A role for the p75 Tumour Necrosis Factor
receptor in lymphocyte development and systemic inflammation.
13th European Immunology Meeting, 22-25 June,
Amsterdam. Published in Immunology letters Vol 56, Abstract
No P.2.0203, p. 93.
Pasparakis M, Alexopoulou L, Douni E, Kollias
G. (1997). Role of the
TNF/LT/receptor development and function of secondary lymhoid organs.
13th European Immunology Meeting,
22-25 June, Amsterdam. Published in Immunology letters Vol
56, Abstract No P.2.06.03, p. 394.
Douni E,
Grell M, Pfizenmaier K, Kollias G. (1996).
Development of local lymphoid-like follicles at
sites of TNF overexpression.
6th International TNF Congress, 8-12 May, Rhodes,
Hellas. Published in European Cytokine Network Vol 7,
Abstract No. 10, p. 164.
Douni E,
Grell M, Pfizenmaier K, Kollias G. (1995).
Transgenic analyses of human p75 TNF receptor
function. The
International Cytokine Society, 3rd Annual Conference,
12-15 September, Harrogate U.K.
Karidis I, Douni E, Mosxogianni C, Karagiorga M, Kollias G,
Haziliami A, Katsantonis A, Tolis G. (1995). Studying the Growth
Hormone axon on children of short and normal height suffering from
Mediterranean Anemia. 22nd Hellenic Endocrinological Conference,
6-9 April, Rio Patra.
Douni E,
Grell M, Pfizenmaier K, Kollias G. (1994).
Probing the function of the human p75 TNF
receptor by its targeted expression in T cells of transgenic mice.
5th International TNF Congress, 31 May -3 June,
Asilomar, California U.S.A. Published in European Cytokine
Network Vol 5, Abstract No. 80, p. 127.
Kollias G, Alexopoulou L, Douni E,
Georgopoulos S, Pasparakis M, Probert L. (1993).
Modeling arthritis in
transgenic mice.
6th French Congress of Rheumatology, 26
November, Paris.
Kollias G, Alexopoulou L, Douni E,
Georgopoulos S, Harami P, Pasparakis M, Probert L. (1993).
Modeling arthritis or a
sepsis-like syndrome in TNF transgenic mice.
Mouse Molecular Genetics,
18-22 August, EMBL Heidelberg.
Kollias G, Douni E, Georgopoulos S, Pasparakis
M, Probert L. (1993).
Analysis of TNF Biology in transgenic mice.
Molecular Mechanisms in Rheumatoid Arthritis
and Related Disease, 31 January-7
February, Keystone Colorado.
Kollias G, Douni E, Georgopoulos S, Harami P,
Pasparakis M,
Probert L. (1993). Modeling arthritis
in transgenic mice. XIII European
Workshop for Rheumatology Research,
28-30 January, Brighton.
Kollias G, Dodou E, Douni E, Georgopoulos S,
Harami P, Pasparakis M, Probert L. (1992).
Transgenic approaches in the
study of TNF Biology. The Cytokine
System in Health and Disease, 8th
Annual Sympossium on Biotechnology, 10-11 December, London.
Probert L, Dodou E, Douni E, Georgopoulos S,
Pasparakis M, Kollias G. (1992). Transgenic models of Human
Tumour Necrosis Factor mediated disease.
Mouse Molecular Genetics,
26-30 August, Cold Spring Harbour.
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