2009 - 2008 - 2007 - 2006 - 2005 - 2004 - 2003 - 2002 - 2001 - 2000 - 1999 - 1998

2010 - (25)

Viejo-Borbolla A, Martin AP, Muniz LR, Shang L, Marchesi F, Thirunarayanan N, Harpaz N, Garcia RA, Apostolaki M, Furtado GC, Mayer L, Kollias G, Alcami A, Lira SA. 2010, "Attenuation of TNF-driven murine ileitis by intestinal expression of the viral immunomodulator CrmD.", Mucosal Immunol. , 2010 Jul 21., [Epub ahead of print] [PubMed].

Papanikolopoulou K, Kosmidis S, Grammenoudi S, Skoulakis EM. 2010, "Phosphorylation differentiates tau-dependent neuronal toxicity and dysfunction.", Biochem Soc Trans., 2010 Aug 1;38(4):, 981-7; [PubMed].

Skoulakis EM, Mudher A. 2010, "Two days of tau: a meeting focused on its biology and pathology.", Biochem Soc Trans, 2010 Aug 1;38(4):, 953-4; [PubMed].

Zouberakis M, Chandras C, Swertz M, Smedley D, Gruenberger M, Bard J, Schughart K, Rosenthal N, Hancock JM, Schofield PN, Kollias G, Aidinis V 2010, "Mouse Resource Browser--a database of mouse databases.", Database (Oxford). , Jul 6 2010, baq010. [PubMed].

Smedley D, Schofield P, Chen CK, Aidinis V., Ainali C, Bard J, Balling R, Birney E, Blake A, Bongcam-Rudloff E, Brookes AJ, Cesareni G, Chandras C, Eppig J, Flicek P, Gkoutos G, Greenaway S, Gruenberger M, Hériché JK, Lyall A, Mallon AM, Muddyman D, Reisinger F, Ringwald M, Rosenthal N, Schughart K, Swertz M, Thorisson GA, Zouberakis M, Hancock JM. 2010, "Finding and sharing: new approaches to registries of databases and services for the biomedical sciences..", Database (Oxford) , Jul 6;2010, baq014 [PubMed].

Chatzigeorgiou A, Harokopos V, Mylona-Karagianni C, Tsouvalas E, Aidinis V, Kamper E. 2010, "The pattern of inflammatory/anti-inflammatory cytokines and chemokines in type 1 diabetic patients over time.", Ann Med. , 2010 Jun 23., [Epub ahead of print] [PubMed].

Kontaki H, Talianidis I. 2010, "Lysine methylation regulates E2F1-induced cell death.", Mol Cell. , 2010 Jul 9 , 39(1):152-60. [PubMed].

Schmidt D, Wilson MD, Ballester B, Schwalie PC, Brown GD, Marshall A, Kutter C, Watt S, Martinez-Jimenez CP, Mackay S, Talianidis I, Flicek P, Odom DT. 2010, "Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding.", Science. , 2010 May 21 , 328(5981):1036-40. Epub 2010 Apr 8. [PubMed].

Ogi T, Limsirichaikul S, Overmeer RM, Volker M, Takenaka K, Cloney R, Nakazawa Y, Niimi A, Miki Y, Jaspers NG, Mullenders LH, Yamashita S, Fousteri MI, Lehmann AR. 2010, "Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.", Mol Cell. , 2010 Mar 12 , 37(5):714-27. [PubMed].

Zaiss MM, Frey B, Hess A, Zwerina J, Luther J, Nimmerjahn F, Engelke K, Kollias G, Hünig T, Schett G, David JP. 2010, "Regulatory T cells protect from local and systemic bone destruction in arthritis.", J Immunol. , 2010 Jun 15 , 184(12):7238-46. Epub 2010 May 17 [PubMed].

Tsangaridou E, Polioudaki H, Sfakianaki R, Samiotaki M, Tzardi M, Koulentaki M, Panayotou G , Kouroumalis E, Castanas E, Theodoropoulos PA., 2010, "Differential detection of nuclear envelope autoantibodies in primary biliary cirrhosis using routine and alternative methods .", BMC Gastroenterol , 10. , 28 [PubMed].

Rapti A, Trangas T, Samiotaki M , Ioannidis P, Dimitriadis E, Meristoudis C, Veletza S, Courtis N. 2010, "The structure of the 5'-untranslated region of mammalian poly(A) polymerase-alpha mRNA suggests a mechanism of translational regulation .", Mol Cell Biochem. , . , Epub ahead of print [PubMed].

Chandris P, Giannouli CC, Panayotou G , Kletsas D. 2010, "Compromise in mRNA processing machinery in senescent human fibroblasts: implications for a novel potential role of Phospho-ATR (ser428) .", Biogerontology. , . , Epub ahead of print [PubMed].

Parapouli M, Fragkos-Livanios L, Samiotaki, M, Koukkou A, Perisynakis A, Hatziloukas E, Panayotou G , Drainas C. 2010, "Comparative proteomic analysis of alcoholic fermentation employing a new environmental strain of Saccharomyces cerevisiae .", Process Biochemistry. , . , Epub ahead of print [PubMed].

Sikara MP, Routsias JG, Samiotaki M, Panayotou G , Moutsopoulos HM, Vlachoyiannopoulos PG. 2010, "β2 glycoprotein I (β2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome .", Blood. , 115. , 713-723 [PubMed].

Gorbenko O, Panayotou G, , Zhyvoloup A, Volkova D, Gout I, Filonenko V. 2010, "Identification of novel PTEN-binding partners: PTEN interaction with fatty acid binding protein FABP4 .", Mol Cell Biochem . , 337. , 299-305 [PubMed].

Xirakia C, Koltsida O, Stavropoulos A, Thanassopoulou A, Aidinis V, Sideras P, Andreakos E. 2010, "TLR7-triggered Immune Response in the Lung Mediates Acute and Long-lasting Suppression of Experimental Asthma.", Am J Respir Crit Care Med. , 2010 Mar 11. , Epub ahead of print [PubMed].

Stamou P, Kontoyiannis DL, 2010, "Posttranscriptional Regulation of TNF mRNA: A Paradigm of Signal-Dependent mRNA Utilization and Its Relevance to Pathology.", Curr Dir Autoimmun., 2010;11:61-79. , Epub 2010 Feb 18. [PubMed].

Blüml S, Binder NB, Niederreiter B, Polzer K, Hayer S, Tauber S, Schett G, Scheinecker C, Kollias G, Selzer E, Bilban M, Smolen JS, Superti-Furga G, Redlich K.. 2010, "Anti-inflammatory effects of TNF on hematopoietic cells in the development of erosive arthritis.", Arthritis Rheum., 2010 Feb 12. , Epub ahead of print [PubMed].

Apostolaki M, Armaka M, Victoratos P, Kollias G. 2010, "Cellular Mechanisms of TNF Function in Models of Inflammation and Autoimmunity.", Curr Dir Autoimmun., 2010;11:1-26, Epub 2010 Feb 18. [PubMed].

Jacques P, Venken K, Van Beneden K, Hammad H, Seeuws S, Drennan MB, Deforce D, Verbruggen G, Apostolaki M, Kollias G, Lambrecht BN, De Vos M, Elewaut D. 2010, "Invariant natural killer T cells are natural regulators of spondyloarthritis.", Arthritis Rheum., 2010 Jan 21. , Epub ahead of print [PubMed].

Fotopoulou S, Oikonomou N, Grigorieva E, Nikitopoulou I, Paparountas T, Thanassopoulou A, Zhao Z, Xu Y, Kontoyiannis DL, Remboutsika E, Aidinis V 2010, "ATX expression and LPA signalling are vital for the development of the nervous system.", Dev Biol., Jan 13. , Epub ahead of print [PubMed].

Kosmidis S, Grammenoudi S, Papanikolopoulou K, Skoulakis EM. 2010, "Differential effects of Tau on the integrity and function of neurons essential for learning in Drosophila.", J Neurosci., 2010 Jan 13;30(2):, 464-77.; [PubMed].

Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J, Wood J, EUMODIC Consortium , de Angelis MH, Brown SD, Hancock JM, Mallon AM., 2010, "EuroPhenome: a repository for high-throughput mouse phenotyping data.", Nucleic Acids Res, 2010 Jan;38(Database issue):, D577-85. Epub 2009 Nov 23.; [PubMed].

Alexiou P, Vergoulis T, Gleditzsch M, Prekas G, Dalamagas T, Megraw M, Grosse I, Sellis T, Hatzigeorgiou AG., 2010, "miRGen 2.0: a database of microRNA genomic information and regulation.", Nucleic Acids Res., 2010 Jan. 38 (Database issue):D137-41. Epub 2009 Oct 22. [Pubmed]

2009 - (40)

Ikonomou, G., Samiotaki, M. and Panayotou, G. 2009, " Proteomic methodologies and their application in colorectal cancer research .", Crit. Rev. Clin. Lab. Sci . , 46. , 319-342 [PubMed].

Psarra AM, Hermann S, Panayotou G, Spyrou G. 2009, "Interaction of mitochondrial thioredoxin with glucocorticoid receptor and NF-kappaBeta modulates glucocorticoid receptor and NF-kappaB signaling in HEK 293 cells .", Biochem J. . , 422. , 521-531 [PubMed].

Stamatakis G, Tsantila N, Samiotaki M, Panayotou GN, , Dimopoulos AC, Halvadakis CP, Demopoulos CA. 2010, "Detection and isolation of antiatherogenic and antioxidant substances present in olive mill wastes by a novel filtration system .", J Agric Food Chem. , 57. , 10554-10564 [PubMed].

Christina Chandras, Thomas Weaver, Michael Zouberakis, Damian Smedley, Klaus Schughart, Nadia Rosenthal, John M. Hancock, George Kollias, Paul N. Schofield, and Aidinis V., 2009, "Models for financial sustainability of biological databases and resources ", Database (2009), Vol. 2009, , bap017; [PubMed].

Martinez-Jimenez CP, Kyrmizi I, Cardot P, Gonzalez FJ, Talianidis I. 2009, "HNF4{alpha} coordinates a transcription factor network regulating hepatic fatty acid metabolism.", Mol Cell Biol., 2009 Nov 23 [Epub ahead of print], [PubMed]

Boj SF, Servitja JM, Martin D, Rios M, Talianidis I. Guigo R, Ferrer J. 2009, "Functional targets of the monogenic diabetes transcription factors HNF-1alpha and HNF-4alpha are highly conserved between mice and humans.", Diabetes. , 2009 May;58(5):1245-53. Epub 2009 Feb 2., [PubMed]

Pampalakis G, Prosnikli E, Agalioti T, Vlahou A, Zoumpourlis V, Sotiropoulou G 2009, "A tumor-protective role for human kallikrein-related peptidase 6 in breast cancer mediated by inhibition of epithelial-to-mesenchymal transition.", Cancer Res. , 2009 May 1;69(9):3779-87. Epub 2009 Apr 21, [PubMed]

Messaritou G, Grammenoudi, S and Skoulakis EMC, 2009, "Dimerization is essential for Drosophila 14-3-3ζ protein stability and function in vivo", J. Biol. Chem, doi/10.1074/jbc.M109.045989, [JBC]

Böhm C, Hayer S, Kilian A, Zaiss MM, Finger S, Hess A, Engelke K, Kollias G, Krönke G, Zwerina J, Schett G, David JP. , 2009, "The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss.", J Immunol. , 2009 Nov 1 183(9):5938-47. Epub 2009 Oct 14 [Pubmed]

Johansen C, Vestergaard C, Kragballe K, Kollias G, Gaestel M, Iversen L., 2009, "MK2 regulates the early stages of skin tumor promotion.", Carcinogenesis, 2009 Oct 6. [Epub ahead of print] [Pubmed]

Tsuji K, Cox K, Gamer L, Graf D, Economides A, Rosen V., 2009, "Conditional deletion of BMP7 from the limb skeleton does not affect bone formation or fracture repair.", J Orthop Res. , 2009 Sep 24. [Epub ahead of print] [Pubmed]

Alexiou P, Maragkakis M, Papadopoulos GL, Reczko M, Hatzigeorgiou AG ., 2009, "Lost in translation: an assessment and perspective for computational microRNA target identification.", Bioinformatics, 2009 Sep 29. [Epub ahead of print] [Pubmed]

Maragkakis M, Alexiou P, Papadopoulos GL, Reczko M, Dalamagas T, Giannopoulos G, Goumas G, Koukis E, Kourtis K, Simossis VA, Sethupathy P, Vergoulis T, Koziris N, Sellis T, Tsanakas P, Hatzigeorgiou AG ., 2009, "Accurate microRNA target prediction correlates with protein repression levels.", BMC Bioinformatics, 2009 Sep 18; 10:295 [Pubmed]

Thwin MM, Douni E, Arjunan P, Kollias G, Kumar PV, Gopalakrishnakone P. 2009, "Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice.", Arthritis Res Ther., 2009 Sep 18;11(5):R138. [Epub ahead of print] , [PubMed]

Charles KA, Kulbe H, Soper R, Escorcio-Correia M, Lawrence T, Schultheis A, Chakravarty P, Thompson RG, Kollias G, Smyth JF, Balkwill FR, Hagemann T. 2009, "The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans.", J Clin Invest., 2009 Sep 8. pii: 39065. doi: 10.1172/JCI39065. [Epub ahead of print] , [PubMed]

Messaritou G, Leptourgidou F. Franco, M and Skoulakis EMC, 2009, "A third functional isoform enriched in mushroom body neurons is encoded by the Drosophila 14-3-3ζ gene", FEBS, Lett. 583: 2934-2938., [PubMed]

Tsiftsoglou AS, Vizirianakis IS, Strouboulis J ., 2009, "Erythropoiesis: Model systems, molecular regulators, and developmental programs", IUBMB Life. ;61(8):800-830. , 2009 Jul 20:61(8), 800-830 [Pubmed]

Kolodziej KE, Pourfarzad F, de Boer E, Krpic S, Grosveld F, Strouboulis J. ., 2009, "Optimal use of tandem biotin and V5 tags in ChIP assays.", BMC Mol Biol. ;, 2009 Feb 5 , 10:6 [Pubmed]

Papadopoulos G, Alexiou P, Maragkakis M, Reczko M, Hatzigeorgiou AG ., 2009, "DIANA-mirPath: Integrating human and mouse microRNAs in pathways.", Bioinformatics, 2009 Aug 1, 25(15):1991-3. Epub 2009 May 12 [Pubmed]

Maragkakis M, Reczko M, Simossis VA, Alexiou P, Papadopoulos GL, Dalamagas T, Giannopoulos G, Goumas G, Koukis E, Kourtis K, Vergoulis T, Koziris N, Sellis T, Tsanakas P, Hatzigeorgiou AG ., 2009, "DIANA-microT web server: elucidating microRNA functions through target prediction.", Nucleic Acids Res, 37(Web Server issue):W273-6. Epub 2009 Apr 30 [Pubmed]

Megraw M, Pereira F, Jensen ST, Ohler U, Hatzigeorgiou AG ., 2009, "A transcription factor affinity based code for mammalian transcription initiation.", Genome Res ,, 19(4): 644-56 [Pubmed]

Papadopoulos GL, Reczko M, Simossis VA, Sethupathy P, Hatzigeorgiou AG ., 2009, "The database of experimentally supported targets: a functional update of TarBase".", Nucleic Acids Research, (Database issue) , D155-8 [Pubmed]

Afantitis A, Melagraki G, Sarimveis H, Koutentis PA, Igglessi-Markopoulou O and Kollias G, 2009, "A combined LS-SVM & MLR QSAR workflow for predicting the inhibition of CXCR3 receptor by quinazolinone analogs", Mol Divers, 2009 May 30. [Epub ahead of print] .[Pubmed]

Olympia Papadaki, Stavros Milatos, Sofia Grammenoudi, Neelanjan Mukherjee, Jack D. Keene and Dimitris L. Kontoyiannis, 2009, "Control of Thymic T Cell Maturation, Deletion and Egress by the RNA-Binding Protein HuR", Journal of Immunology, 182: 6779-6788. .[Pubmed]

Sotiria Tzima, Panayiotis Victoratos, Ksanthi Kranidioti, Maria Alexiou and George Kollias, 2009, "Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production", J Exp Med, doi:10.1084/jem.20081582 .[Pubmed]

Maria Armaka, Vassiliki Gkretsi, Dimitris Kontoyiannis and George Kollias, 2009, "A standardized protocol for the isolation and culture of normal and arthritogenic murine synovial fibroblasts .", Nature Protocols , DOI: 10.1038/nprot.2009.102 .[Nature Protocols]

MacKenzie B, Wolff R, Lowe N, Billington CJ Jr,, Peterson A, Schmidt B, Graf D, Mina M, Gopalakrishnan R, Petryk A, 2009, "Twisted gastrulation limits apoptosis in the distal region of the mandibular arch in mice.", Dev Biol , 328: , 13-2 .[Pubmed]

Liu X, Alexiou M, Martin-Orozco N, Chung Y, Nurieva RI, Ma L, Tian Q, Kollias G, Lu S, Graf D, Dong C., 2009, "Cutting edge: A critical role of B and T lymphocyte attenuator in peripheral T cell tolerance induction.", J Immunol., 2009 Apr 15, 182(8):4516-20 .[Pubmed]

Zouvelou V, Passa O, Segklia K, Tsalavos S, Valenzuela DM, Economides AN, Graf D. , 2009, "Generation and functional characterization of mice with a conditional BMP7 allele.", Int J Dev Biol., 2009 Feb 26, [Epub ahead of print] .[Pubmed]

Zouvelou V, Luder HU, Mitsiadis TA, Graf D. , 2009, "Deletion of BMP7 affects the development of bones, teeth, and other ectodermal appendages of the orofacial complex.", J Exp Zoolog B Mol Dev Evol., 2009 Jan 6, Epub ahead of print .[Pubmed]

Kotsianidis I, Nakou E, Bouchliou I, Tzouvelekis A, Spanoudakis E, Steiropoulos P, Sotiriou I, Aidinis V., Margaritis D, Tsatalas C, Bouros D., 2009, "Global Impairment of CD4+CD25+FOXP3+ T Regulatory Cells in Idiopathic Pulmonary Fibrosis.", Am J Respir Crit Care Med., Apr 2, [Epub ahead of print] [PubMed].

Katsanou V, Milatos S, Yiakouvaki A, Sgantzis N, Kotsoni A, Alexiou M, Harokopos V, Aidinis V., Hemberger M, Kontoyiannis DL., 2009, "The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development.", Mol Cell Biol., May 29 , 10:2762-76 [PubMed].

Eirini Trompouki, Ageliki Tsagaratou, Stylianos K Kosmidis, Pascal Dolle, Jun Qian, Dimitris L Kontoyiannis, Wellington V. Cardoso and George Mosialos, 2009, "Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation ", Neoplasia, Volume 11, Issue 5 [Abstract].

Tzouvelekis A, Aidinis V, Harokopos V, Karameris A, Zacharis G, Mikroulis D, Konstantinou F, Steiropoulos P, Sotiriou I, Froudarakis M, Pneumatikos I, Tringidou R, Bouros D. , 2009, "Down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis.", Respir Res. , Feb 27. 10(1):14.[Epub ahead of print] [Pubmed].

Anastasios Moressis, Anke R. Friedrich, Elias Pavlopoulos, Ronald L. Davis Efthimios M. C. Skoulakis, 2009, "A Dual Role for the Adaptor Protein DRK in Drosophila Olfactory Learning and Memory .", J. Neurosci. , 2009 29: 2611-2625., [PubMed]

Oikonomou N, Thanassopoulou A, Tzouvelekis A, Harokopos V, Paparountas T, Nikitopoulou I, Witke W, Karameris A, Kotanidou A, Bouros D, and Aidinis V., 2009, "Gelsolin expression is necessary for the development of modelled pulmonary inflammation and fibrosis.", Thorax. , Feb 12. [Epub ahead of print] [Pubmed].

Melagraki G, Afantitis A, Sarimveis H, Koutentis PA, Kollias G, Igglessi-Markopoulou O. 2009, "Predictive QSAR workflow for the in silico identification and screening of novel HDAC inhibitors.", Mol Divers. , [Epub ahead of print], [PubMed].

Huang CH, Vallejo JG, Kollias G, Mann DL. 2009, "Role of the Innate Immune System in Acute Viral Myocarditis.", Basic Res Cardiol. , [Epub ahead of print], [PubMed].

Victoratos P, Kollias G . 2009, "Induction of autoantibody-mediated spontaneous arthritis critically depends on follicular dendritic cells.", Immunity , 30(1):130-42 , [PubMed].

2008 - (31)

Oehrl W. and Panayotou, G. 2008, "Modulation of growth factor action by the extracellular matrix .", Connect Tissue Res . , 49. , 145-148 [PubMed].

Petroutsos D, Katapodis P, Samiotaki M, Panayotou G , Kekos D. 2008, "Detoxification of 2,4-dichlorophenol by the marine microalga Tetraselmis marina .", Phytochemistry , 69. , 707-714 [PubMed].

Gareus R, Kotsaki E, Xanthoulea S, van der Made I, Gijbels MJ, Kardakaris R, Polykratis A,, Kollias G, de Winther MP, Pasparakis M. 2008, "Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis.", Cell Metab. , 2008 Nov;8(5):372-83, [PubMed].

Zouberakis M., Chandras C., Hancock J.M., Schofield P.N., and Aidinis V., 2008, "The Mouse Resource Browser (MRB) - A near-complete registry of mouse resources", BioInformatics and BioEngineering, 2008. BIBE 2008. , 8th IEEE International Conference on 8-10 Oct. Page(s):1 - 5 [IEEEXplore].

Hancock J.M., Schofield P.N., Chandras C., Zouberakis M, Aidinis V., Smedley D., Rosenthal N., and Schughart K., 2008, "CASIMIR: Coordination and Sustainability of International Mouse Informatics Resources", BioInformatics and BioEngineering, 2008. BIBE 2008. , 8th IEEE International Conference on 8-10 Oct. Page(s):1 - 6 [IEEEXplore].

Swertz M.A., Smedley D., Wolstencroft K., Alberts R., Zouberakis M., Aidinis V.,Schughart K., Schofield P.N., and Jansen R.C., 2008, "Towards dynamic database infrastructures for mouse genetics", BioInformatics and BioEngineering, 2008. BIBE 2008. , 8th IEEE International Conference on 8-10 Oct. Page(s):1 - 7 [IEEEXplore].

Kazama I, Mahoney Z, Miner JH, Graf D, Economides AN, Kreidberg JA., 2008, "Podocyte-derived BMP7 is critical for nephron development.", J Am Soc Nephrol., 2008 Nov, 19(11):2181-91 .[Pubmed]

Stathopoulos GT, Psallidas I, Moustaki A, Moschos C, Kollintza A, Karabela S, Porfyridis I, Vassiliou S, Karatza M, Zhou Z, Joo M, Blackwell TS, Roussos C, Graf D, and I Kalomenidis., 2008, "A Central Role for Tumor-derived Monocyte Chemoattractant Protein-1 in Malignant Pleural Effusion.", J Natl Cancer Inst., 100, 1464-1476 .[Pubmed]

Graf D, and Economides AN., 2008, "Dissection of BMP signaling using genome engineering tools (2008) in ‘Bone Morphogenetic Proteins: From Local to Systemic Therapeutics.", edited by Slobodan Vukicevic and Kuber T. Sampath. Series: Progress in Inflammation Research, Birkhauser Verlag, , pp115-139 .[springer.com]

Pavlopoulos E, Anezaki M, Skoulakis EM, 2008, "Neuralized is expressed in the {alpha}/{beta} lobes of adult Drosophila mushroom bodies and facilitates olfactory long-term memory formation..", Proc Natl Acad Sci U S A. , 2008 Sep 15.[Epub ahead of print], [PubMed].

Tatarakis A, Margaritis T, Martinez-Jimenez CP, Kouskouti A, Mohan WS 2nd, Haroniti A, Kafetzopoulos D, Tora L, Talianidis I, 2008, "Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.", Mol Cell. , 2008 Aug 22;31(4):531-43., [PubMed].

Hamlett I, Draper J, Strouboulis J, Iborra F, Porcher C, Vyas P. 2008, "Characterisation of megakaryocyte GATA1-interacting proteins: the co-repressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturation.", Blood. , 2008 Jul 14. [Epub ahead of print], [PubMed].

Liang S, Moghimi B, Yang TP, Strouboulis J, Bungert J 2008, "Locus control region mediated regulation of adult beta-globin gene expression.", J Cell Biochem. , 2008 Sep 1;105(1):9-16, [PubMed].

Büning J, von Smolinski D, Tafazzoli K, Zimmer KP, Strobel S, Apostolaki M, Kollias G, Heath JK, Ludwig D, Gebert A. 2008, "Multivesicular bodies in intestinal epithelial cells: responsible for MHC class II-restricted antigen processing and origin of exosomes.", Immunology. , 2008 Aug 14. [Epub ahead of print], [PubMed].

Kawahara Y, Megraw M, Kreider E, Iizasa H, Valente L, Hatzigeorgiou AG, Nishikura K. 2008, "Frequency and fate of microRNA editing in human brain.", Nucleic Acids Res. , 2008 Aug 6. [Epub ahead of print], [PubMed].

Ermolaeva MA, Michallet MC, Papadopoulou N, Utermöhlen O, Kranidioti K, Kollias G, Tschopp J, Pasparakis M. 2008, "Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses.", Nat Immunol. , 2008 Sep;9(9):1037-46. Epub 2008 Jul 20, [Pubmed].

Allie N, Alexopoulou L, Quesniaux VJ, Fick L, Kranidioti K, Kollias G, Ryffel B, Jacobs M. 2008, "Protective role of membrane tumour necrosis factor in the host's resistance to mycobacterial infection.", Immunology, 2008 Jun 9, [Pubmed].

Pullerits R, Jonsson IM, Kollias G, Tarkowski A. 2008, "Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling.", Arthritis Res Ther, 2008;10(3):R72, [Pubmed].

Thireos G, Panayotou G. ,Thanos D. , 2008, "Biochemistry and molecular biology research achievements in Greece.", IUBMB Life, 2008 May;60(5), 254-7 [PubMed].

Lionaki E, de Marcos Lousa C, Baud C, Vougioukalaki M, Panayotou G. , Tokatlidis K., 2008, "The Essential Function of Tim12 in Vivo Is Ensured by the Assembly Interactions of Its C-terminal Domain.", J Biol Chem., 2008 Jun 6, 283(23):15747-53 [PubMed].

Koliaraki V, Marinou M, Samiotaki M, Panayotou G., Pantopoulos K, Mamalaki A., 2008, "Iron regulatory and bactericidal properties of human recombinant hepcidin expressed in Pichia pastoris.", Biochimie., 2008 May, 90(5):726-35 [PubMed].

Zhang L, Volinia S, Bonome T, Calin GA, Greshock J, Yang N, Liu CG, Giannakakis A, Alexiou P, Hasegawa K, Johnstone CN, Megraw MS, Adams S, Lassus H, Huang J, Kaur S, Liang S, Sethupathy P, Leminen A, Simossis VA, Sandaltzopoulos R, Naomoto Y, Katsaros D, Gimotty PA, DeMichele A, Huang Q, Bützow R, Rustgi AK, Weber BL, Birrer MJ, Hatzigeorgiou AG, Croce CM, Coukos G. 2008, "Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer.", Proc Natl Acad Sci U S A., 2008 May 13 105(19):7004-9. Epub 2008 May 5., [PubMed].

Antreas Afantitis, Georgia Melagraki, Haralambos Sarimveis, Olga Igglessi-Markopoulou, Kollias G, 2008, "A novel QSAR model for predicting the inhibition of CXCR3 receptor by 4-N-aryl-[1,4]diazepane ureas", European Journal of Medicinal Chemistry, 2008.05.028, [ScienceDirect].

Apostolaki M, Manoloukos M, Roulis M, Wurbel MA, Müller W, Papadakis KA, Kontoyiannis DL, Malissen B, Kollias G 2008, "Role of beta7 Integrin and the Chemokine/Chemokine Receptor Pair CCL25/CCR9 in Modeled TNF-Dependent Crohn's Disease", Gastroenterology., 2008 Mar 5, Epub ahead of print [PubMed].

Grammenoudi S, Anezaki M, Kosmidis S, Skoulakis EM., 2008, "Modelling cell and isoform type specificity of tauopathies in Drosophila.", SEB Exp Biol Ser., 2008;60, 39-56 [PubMed - in process]

Huybers S, Apostolaki M, van der Eerden BC, Kollias G, Naber TH, Bindels RJ, Hoenderop JG. 2008, "Murine TNF(DeltaARE) Crohn's disease model displays diminished expression of intestinal Ca(2+) transporters", Inflamm Bowel Dis., 2008 Feb 11, Epub ahead of print [PubMed].

Maria Armaka, Maria Apostolaki, Peggy Jacques, Dimitris L. Kontoyiannis, Dirk Elewaut, Kollias G. 2008, "Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases", J Exp Med., 2008 Feb 4, 10.1084/jem.20070906. [PubMed].

Schurigt U, Hummel KM, Petrow PK, Gajda M, Stöckigt R, Middel P, Zwerina J, Janik T, Bernhardt R, Schüler S, Scharnweber D, Beckmann F, Saftig P, Kollias G, Schett G, Wiederanders B, Bräuer R. 2008, "Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice", Arthritis Rheum., 2008 Jan 31, 58(2):422-434. [PubMed].

Koutroubas G, Merika M, Thanos D, 2008, "Bypassing the requirements for epigenetic modifications in gene transcription by increasing enhancer strength.", Mol Cell Biol., 2008 Feb, 28(3):926-38. [PubMed].

Bobacz K, Sunk IG, Hayer S, Amoyo L, Tohidast-Akrad M, Kollias G ,Smolen JS, Schett G. 2008, "Differentially regulated expression of growth differentiation factor 5 and bone morphogenetic protein 7 in articular cartilage and synovium in murine chronic arthritis: Potential importance for cartilage breakdown and synovial hypertrophy.", Arthritis Rheum., 2008 Jan; 58(1):109-18 [PubMed].

2007 - (28)

Maratheftis CI, Giannouli S, Spachidou MP, Panayotou G., Voulgarelis M., 2007, "RNA interference of interferon regulatory factor-1 gene expression in THP-1 cell line leads to Toll-like receptor-4 overexpression/activation as well as up-modulation of annexin-II.", Neoplasia., 2007 Dec, 9(12):1012-20 [PubMed].

Karanasios E, Simader H, Panayotou G., Suck D, Simos G., 2007, "Molecular determinants of the yeast Arc1p-aminoacyl-tRNA synthetase complex assembly.", J Mol Biol., 2007 Dec 7, 374(4):1077-90 [PubMed].

Petroutsos D, Katapodis P, Samiotaki M, Panayotou G., Kekos D., 2007, "Detoxification of 2,4-dichlorophenol by the marine microalga Tetraselmis marina.", Phytochemistry, 2008 Feb, 69(3):707-14 [PubMed].

Tsimogiannis D, Samiotaki M, Panayotou G., Oreopoulou V., 2007, "Characterization of flavonoid subgroups and hydroxy substitution by HPLC-MS/MS.", Molecules, 2007 Mar 21, 12(3):593-606 [PubMed].

Oikonomou N., Harokopos V., Zalevsky J., Valavanis C., Kotanidou A., Szymkowski D.E., Kollias G. and, Aidinis V., 2007, "Soluble TNF Mediates the Transition from Pulmonary Inflammation to Fibrosis.", PLoS One, [Pubmed].

Tzortzopoulos A, Skoulakis EM., 2007, "Paternally and maternally transmitted GAL4 transcripts contribute to UAS transgene expression in early Drosophila embryos.", Genesis , 2007 Dec;45, (12):737-43. [PubMed - in process]

Sanyal S, Båvner A, Haroniti A, Nilsson LM, Lundåsen T, Rehnmark S, Witt MR, Einarsson C, Talianidis I,Gustafsson JA, Treuter E. 2007, "Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis.", Proc Natl Acad Sci U S A., 2007 Oct 2, 104(40):15665-70. Epub 2007 Sep 25. [PubMed].

Venteclef N, Haroniti A, Tousaint JJ, Talianidis I, Delerive P, 2007, "Regulation of anti-atherogenic apolipoprotein M gene expression by the orphan nuclear receptor LRH-1.", J Biol Chem., 2007 Oct 31, [Epub ahead of print] [PubMed].

Vasilopoulos Y, Gkretsi V, Armaka M, Aidinis V, Kollias G, 2007, "Actin cytoskeleton dynamics linked to synovial fibroblast activation as a novel pathogenic principle in TNF-driven arthritis.", Ann Rheum Dis., 2007 Nov, 66 Suppl 3:iii23-8 [PubMed].

Douni E, Armaka M,Kontoyiannis DL, Kollias G 2007, "Functional genetic and genomic analysis of modeled arthritis.", Adv Exp Med Biol., 2007, 602:33-42. [PubMed in process].

Stathopoulos GT, Kollintza A, Moschos C, Psallidas I, Sherrill TP, Pitsinos EN, Vassiliou S, Karatza M, Papiris SA, Graf D, Orphanidou D, Light RW, Roussos C, Blackwell TS, Kalomenidis I., 2007, "Tumor Necrosis Factor-{alpha} Promotes Malignant Pleural Effusion.", Cancer Res., 2007 Oct 15,, 67(20):9825-34. [Pubmed]

Aidinis V, Chandras C, Manoloukos M, Thanassopoulou A, Kranidioti K, Armaka M, Douni E, Kontoyiannis DL, Zouberakis M, Kollias G, the Mugen NoE consortium., 2007, "MUGEN mouse database; Animal models of human immunological diseases.", Nucleic Acids Res., Oct 11 Pubmed

Katsantoni, E.Z., Anghelescu, N.E., Rottier, R., Moerland, M., Antoniou, M., de Crom, R., Grosveld, F. and Strouboulis J., 2007, "Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island", BMC Dev Biol, 2007 Sep 27, 7(1):108.Epub ahead of print. PubMed

Acevedo SF, Tsigkari KK, Grammenoudi S, Skoulakis E., 2007, "In vivo functional specificity and homeostasis of Drosophila 14-3-3 proteins.", Genetics, 2007 Sep;177, (1):239-53.Epub 2007 Jul 29. [PubMed - in process]

Missirlis F, Kosmidis S, Brody T, Mavrakis M, Holmberg S, Odenwald WF, Skoulakis E. Rouault TA., 2007, "Homeostatic mechanisms for iron storage revealed by genetic manipulations and live imaging of Drosophila ferritin.", Genetics , 2007 Sep;177, (1):89-100.Epub 2007 Jul 1. [PubMed - in process]

Tsichritzis T, Gaentzsch PC, Kosmidis S, Brown AE, Skoulakis E., Ligoxygakis P, Mosialos G., 2007, "A Drosophila ortholog of the human cylindromatosis tumor suppressor gene regulates triglyceride content and antibacterial defense.", Development , 2007 Jul;134, (14):2605-14.Epub 2007 Jun 6. [PubMed - in process]

Van Molle W, Van Roy M, Van Bogaert T, Dejager L, Van Lint P, Vanlaere I, Sekikawa K, Kollias G, Libert C. 2007, "Protection of zinc against tumor necrosis factor induced lethal inflammation depends on heat shock protein 70 and allows safe antitumor therapy.", Cancer Res., 2007 Aug 1, 67(15):7301-7. [PubMed]

Argyris Tzouvelekis, Vaggelis Harokopos, Triantafillos Paparountas, Nikos Oikonomou, Aristotelis Chatziioannou, George Vilaras, Evangelos Tsiambas,Andreas Karameris, Demosthenes Bouros and Aidinis V., 2007, "Pulmonary Fibrosis Comparative Expression Profiling Suggests Key Role of Hypoxia Inducible Factor 1a", Am J Respir Crit Care Med, Aug 30. [Pubmed]

Chatzidakis I, Fousteri G, Tsoukatou D, Kollias G, Mamalaki C. 2007, "An essential role for TNF in modulating thresholds for survival, activation, and tolerance of CD8+ T cells.", J Immunol., 2007 Jun 1, 178(11):6735-45. PubMed

The Mouse Phenotype Database Integration Consortium ( John M. Hancock, Niels C. Adams, Aidinis V., Andrew Blake, Judith A. Blake, Molly Bogue, Steve D. M. Brown, Elissa Chesler, Duncan Davidson, Christopher Duran, Janan T. Eppig, Valerie Gailus-Durner, Hilary Gates, Georgios V. Gkoutos, Simon Greenaway, Martin Hrabe´ De Angelis, Kollias George, Sophie Leblanc, Kirsty Lee, Christoph Lengger, Holger Maier, Ann-Marie Mallon, Hiroshi Masuya, David G. Melvin, Werner Mu ller, Helen Parkinson, Glenn Proctor, Eli Reuveni, Paul Schofield, Aadya Shukla, Cynthia Smith, Tetsuro Toyoda, Laurent Vasseur, Shigeharu Wakana, Alison Walling, Jacqui White, Joe Wood, Michalis Zouberakis), 2007, "Integration of mouse phenome data resources", Mamm. Genome. , 18(3):157-63 [Pubmed]

Moerland, M., Anghelescu, N., Samyn, H., van Haperen, R., van Gent, T., Strouboulis, J., van Tol, A., Grosveld, F. and de Crom, R. 2007, "Inducible expression of phospholipid transfer protein (PLTP) in transgenic mice: acute effects of PLTP on lipoprotein metabolism." Transgenic Res, 2007 Apr 17, [Epub ahead of print] [Pubmed]

Summer F. Acevedo, Emmanuil I. Froudarakis, Alexandros Kanellopoulos, Skoulakis E. , 2007, "Protection from premature habituation requires functional mushroom bodies in Drosophila.", Learn. Mem. , 2007, 14: 376-384 [pdf].

Skopeliti M, Kratzer U, Altenberend F, Panayotou G, Kalbacher H, Stevanovic S, Voelter W, Tsitsilonis OE. 2007, "Proteomic exploitation on prothymosin alpha-induced mononuclear cell activation.", Proteomics, 7, 1814-1824 [PubMed]

Fragopoulou E, Nomikos T, Karantonis HC, Apostolakis C, Pliakis E, Samiotaki M, Panayotou G,Antonopoulou S. 2007, "Biological activity of acetylated phenolic compounds.", J Agric Food Chem., 2007 Jan 10, 55(1):80-9 [PubMed]

Yang Y, Liu XK, Nguyen T, Bishop C, Graf D, Dong C. 2007, "Characterization of B7S3 as a Novel Negative Regulator of T Cells", J Immunol., Mar 15, 178(6):3661-7. [PubMed].

Ye P, Kollias G, D'Ercole AJ. 2007, "Insulin-like growth factor-I ameliorates demyelination induced by tumor necrosis factor-alpha in transgenic mice.", J Neurosci Res., 2007 Feb 5, 85(4):712-722 [Epub ahead of print] [PubMed].

Sanchez C, Sanchez I, Demmers JA, Rodriguez P, Strouboulis J, Vidal M. 2007, "Proteomic analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/ Jmjd1B histone demethylase and the BcoR corepressor.", Mol Cell Proteomics., 2007 Feb 11, [PubMed].

Stea EA, Routsias JG, Samiotaki M, Panayotou G, Papalambros E, Moutsopoulos HM, Tzioufas AG. 2007, "Analysis of parotid glands of primary Sjogren's syndrome patients using proteomic technology reveals altered autoantigen composition and novel antigenic targets.", Clin Exp Immunol, 2007 Jan, ;147(1):81-9, [PubMed].

2006 - (20)

Acevedo SF, Froudarakis EI, Tsiorva AA, Skoulakis E., 2006, "Distinct neuronal circuits mediate experience-dependent, non-associative osmotactic responses in Drosophila.", Mol Cell Neurosci., 2006 Dec 29, [Epub ahead of print] [PubMed].

Maglogiannis .I, Sarimveis H.,Kiranoudis C., Chatziioannou A.A., Oikonomou N. and, Aidinis V., 2006, "Radial Basis Function neural networks classification for the recognition of idiopathic pulmonary fibrosis in microscopic images", IEEE Trans Inf Technol Biomed, [PubMeb].

Cobb BS, Hertweck A, Smith J, O'connor E, Graf D, Cook T, Smale ST, Sakaguchi S, Livesey FJ, Fisher AG, Merkenschlager M. 2006, "A role for Dicer in immune regulation.", J Exp Med., 2006 Oct 23, Epub ahead of print. [PubMed].

Agelopoulos M, Thanos D , 2006, "Epigenetic determination of a cell-specific gene expression program by ATF-2 and the histone variant macroH2A.", EMBO J., 2006 Oct 18, 25(20):4843-4853. Epub 2006 Oct 12. [PubMed].

Alexopoulou L, Kranidioti K, Xanthoulea S, Denis M, Kotanidou A, Douni E, Blackshear PJ, Kontoyiannis DL, Kollias G, 2006, "Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity.", Eur J Immunol., 2006 Oct 36(10): 2768-80. [PubMed].

Janssens R, Dekker S, Hendriks RW, Panayotou G,Van Remoortere A, Kong-A San J, Grosveld F, Drabek D, 2006, "Generation of heavy-chain-only antibodies in mice.", Proc Natl Acad Sci U S A., 2006 Oct 2, Epub ahead of print. [PubMed].

Lindtner S, Zolotukhin AS, Uranishi H, Bear J, Kulkarni V, Smulevitch S, Samiotaki M, Panayotou G, Felber BK, Pavlakis GN., 2006, "RBM15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway.", J Biol Chem., 2006 Sep 25, Epub ahead of print. [PubMed].

Mylonis I, Chachami G, Samiotaki M, Panayotou G, Paraskeva E, Kalousi A, Georgatsou E, Bonanou S, Simos G., 2006, "Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor 1a.", J Biol Chem., 2006 Sep 5, Epub ahead of print. [PubMed].

Hatzivassiliou EG, Kieff E, Mosialos G., 2006, "Constitutive CD40 signaling phenocopies the transforming function of the Epstein-Barr virus oncoprotein LMP1 in vitro.", Leuk Res., 2006 Aug 16 Epub ahead of print. [PubMed].

Grammenoudi S. ,Kosmidis S. ,Skoulakis E, 2006, "Cell type-specific processing of human Tau proteins in Drosophila.", FEBS Letter, Volume 580, Issue 19, 4602-4606. [PubMed].

Tsoupras AB, Antonopoulou S, Baltas G, Samiotaki M, Panayotou G, Kotsifaki H, Mantzavinos Z, Demopoulos CA., 2006, "Isolation and identification of hydroxyl-platelet-activating factor from natural sources.", Life Sci., 2006 Oct 4, 79(19):1796-803.Epub 2006 Jun 14. [PubMed].

Boillee S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G ,Cleveland DW, 2006, "Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia.", Science, 2006 Jun 2, 312(5778):1389-92. [PubMed].

Bamias G, Mishina M, Nyce M, Ross WG, Kollias G, Rivera-Nieves J, Pizarro TT, Cominelli F, 2006, "Role of TL1A and its receptor DR3 in two models of chronic murine ileitis.", Proc Natl Acad Sci USA, 2006 May 30, 103(22):8441-6 [PubMed].

Skoulakis E,Grammenoudi S., 2006, "Dunces and da Vincis: the genetics of learning and memory in Drosophila", Cell Mol Life Sci., 2006 May, 63(9):975-88. [PubMed].

Argyropoulos C, Chatziioannou AA, Nikiforidis G, Moustakas A, Kollias G, Aidinis V, 2006, "Operational Criteria For Selecting a cDNA Microarray Data Normalization Algorithm.", Oncol Rep., 2006, 15, :983-96 [PubMed].

Zwerina J, Hayer S, Redlich K, Bobacz K, Kollias G, Smolen JS, Schett G., 2006, "Activation of p38 MAPK is a key step in tumor necrosis factor-mediated inflammatory bone destruction.", Arthritis Rheum., 2006 Jan 30, 54:463-472. [PubMed].

Victoratos P, Lagnel J, Tzima S, Alimzhanov MB, Rajewsky K, Pasparakis M, Kollias G, 2006, "FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses." Immunity, 2006 Jan, 24:65-77. [PubMed].

Tzimas C, Michailidou G, Arsenakis M, Kieff E,Mosialos G. , Hatzivassiliou EG., 2006, "Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-kappaB." , Cell Signal, 2006 Jan, 18(1):83-92 [PubMed].

Vynios DH, Tsagaraki I, Grigoreas GH, Samiotaki M, Panayotou G, Kyriakopoulou D, Georgiou P, Korbakis D, Panayotou A, Nanouri K, Assouti M, Andonopoulos AP., 2006, "Isolation and identification of hydroxyl-platelet-activating factor from natural sources.", Biochimie, 2006 Jul, 88(7):767-73. Epub 2006 Jan 30. [PubMed].

Trougakos IP, Saridaki A, Panayotou G, Gonos ES., 2006, "Identification of differentially expressed proteins in senescent human embryonic fibroblasts.", Mech Ageing Dev., 2006 Jan, 127(1):88-92. Epub 2005 Oct 5. PubMed].

2005 - (14)

Beardmore VA, Hinton HJ, Eftychi C, Apostolaki M, Armaka M, Darragh J, McIlrath J, Carr JM, Armit LJ, Clacher C, Malone L, Kollias G, Arthur JS., 2005, "Generation and Characterization of p38{beta} (MAPK11) Gene-Targeted Mice", Mol Cell Biol., 2005 Dec, 25:10454-10464 . PubMed

Hayer S, Tohidast-Akrad M, Haralambous S, Jahn-Schmid B, Skriner K, Trembleau S, Dumortier H, Pinol-Roma S, Redlich K, Schett G, Muller S, Kollias G, Smolen J, Steiner G., 2005, "Aberrant expression of the autoantigen heterogeneous nuclear ribonucleoprotein-A2 (RA33) and spontaneous formation of rheumatoid arthritis-associated anti-RA33 autoantibodies in TNF-alpha transgenic mice.",  J Immunol., 2005 Dec 15, 175(12):8327-36. PubMed

Hovelmeyer N, Hao Z, Kranidioti K, Kassiotis G, Buch T, Frommer F, von Hoch L, Kramer D, Minichiello L, Kollias G , Schett G., 2005, "Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune Encephalomyelitis ", J Immunol., 2005 Nov 1;175(9), 5875-84 . PubMed

Kaplan, Frederick S.; Shore, Eileen M.; Gupta, Rishi; Billings, Paul C.; Glaser, David L.; Pignolo, Robert J.; Graf, Daniel; Kamoun, Malek, 2005 "Immunological Features of Fibrodysplasia Ossificans Progressiva and the Dysregulated BMP4 Pathway" Clinical Review in Bone and Mineral Metabolism, Volume 3, Numbers 3-4, October 2005, pp. 189-194, Publisher: Humana Press 

Aidinis V, Carninci P, Armaka M, Witke W, Harokopos V, Pavelka N, Koczan D, Argyropoulos C, Thwin MM, Moller S, Kazunori W, Gopalakrishnakone P, Ricciardi-Castagnoli P, Thiesen HJ, Hayashizaki Y,Kollias G, 2005, "Cytoskeletal rearrangements in synovial fibroblasts as a novel pathophysiological determinant of modeled rheumatoid arthritis",  PLoS Genet., 2005 Oct, 1:e48 . PubMed

Zwerina J, Tzima S, Hayer S, Redlich K, Hoffmann O, Hanslik-Schnabel B, Smolen JS, Kollias G , Lassmann H, Waisman A., 2005, "Heme oxygenase 1 (HO-1) regulates osteoclastogenesis and bone resorption", FASEB J., 2005 Oct 18, PubMed

Saridaki A, Panayotou G. 2005  "Identification of growth factor-regulated proteins using 2D electrophoresis and mass spectrometry". Growth Factors. 2005 Sep;23:223-32. PubMed

Katsanou V., Papadaki O., Milatos S., Blackshear P., Anderson P., Kollias G. and , Kontoyiannis D. , 2005, "HuR as a Negative Posttranscriptional Modulator in Inflammation", Mol. Cell., 19, 777-789 [ Mol. Cell]. PubMed

Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G.,  Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schonbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y; FANTOM Consortium; RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)., 2005, "The transcriptional landscape of the mammalian genome", Science 2005 Sep 2;309, 1559-63 . PubMed

Wang L, Baiocchi RA, Pal S, Mosialos G, Caligiuri M, Sif S. 2005 "The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene". Mol Cell Biol. 2005 Sep;25:7953-65. PubMed

Tzimas C, Michailidou G, Arsenakis M, Kieff E, Mosialos G, Hatzivassiliou EG. 2005 "Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-kappaB". Cell Signal. 2006 Jan;18 :83-92. Epub 2005 Apr 26. PubMed

Alexopoulou L., Kontoyiannis D., 2005, "Contribution of microbial-associated molecules in innate mucosal responses", CMLS, Cell.Mol.Life Sci., 62, 1349-58 . PubMed

Hatzivassiliou EG, Tsichritzis T, Mosialos G. Related Articles, Links 2005 "Induction of apoptosis by rewiring the signal transduction of Epstein-Barr virus oncoprotein LMP1 toward caspase activation". J Virol. 2005 Apr;79:5215-9. PubMed

Ligoudistianou C, Xu Y, Garnier G, Circolo A, Volanakis JE. 2005  "A novel human complement-related protein, C1r-like protease (C1r-LP), specifically cleaves pro-C1s." Biochem J. 2005 Apr 1;387(Pt 1):165-73. PubMed

2004 - (22)

Panagopoulos D, Victoratos P, Alexiou M, Kollias G, Mosialos G. 2004 "Comparative analysis of signal transduction by CD40 and the Epstein-Barr virus oncoprotein LMP1 in vivo". J Virol. 2004 Dec;78(23):13253-61. PubMed

Auwerx J., Avner P., Baldock R., Ballabio A., Balling R., Barbacid M., Berns A., Bradley A., Brown S., Carmeliet P., Chambon P., Cox R., Davidson D., Davies K., Duboule D., Forejt J., Granucci F., Hastie N., de Angelis M. H., Jackson I., Kioussis D., Kollias G., Lathrop M., Lendahl U., Malumbres M., von Melchner H., Muller W., Partanen J., Ricciardi-Castagnoli P., Rigby P., Rosen B., Rosenthal N., Skarnes B., Stewart AF, Thornton J., Tocchini-Valentini G., Wagner E., Wahli W., Wurst W., 2004, "The European dimension for the mouse genome mutagenesis program", Nat. Genetics, 36, 925-7 . PubMed

Xanthoulea S., Pasparakis M., Kousteni S., Brakebusch C., Wallach D., Bauer J., Lassmann H., Kollias G., 2004,  "Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases", J. Exp. Med., 2;200 (3), 367-76 . PubMed

Kollias G., 2004, "Modeling the function of tumor necrosis factor in immune pathophysiology", Autoimmun. Rev., 3 Suppl 1, S24-5 . PubMed

Herrak P., Gortz B., Hayer S., Redlich K., Reiter E., Gasser J., Bergmeister H., Kollias G., Smolen J. S., Schett G., 2004, "Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis", Arthritis Rheum., 50 (7), 2327-37. PubMed 

Jono H., Lim J. H., Chen L. F., Xu H., Trompouki E., Pan Z. K., Mosialos G., Li J. D., 2004, "NF-κB Is Essential for Induction of CYLD, the Negative Regulator of NF-κB: Evidence for A Novel Inducible Auto-Regulatory Feedback Pathway", J. Biol. Chem., 279, 36171-36174 . PubMed

Smolen J. S., Hayer S., Schett G., Redlich K., Aringer M., Kollias G., Wagner E., Steiner G., 2004, "Autoimmunity and rheumatoid arthritis", Autoimmun. Rev., 3 Suppl 1, S23 . PubMed

Thwin M. M., Douni E., Aidinis V., Kollias G., Kodama K., Sato K., Satish R. L., Mahendran R., Gopalakrishnakone P., 2004, "Effect of phospholipase A2 inhibitory peptide on inflammatory arthritis in a TNF transgenic mouse model: a time-course ultrastructural study", Arthritis Res. & Ther., 6 (3), R282-94 . PubMed

Staelens J., Puimege L., Mahieu T., Pynaert G., Hochepied T., Vandenabeele A., Grooten J., Kontoyiannis D., Van Roy F., Kollias G., Libert C., 2004, "Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders", Mamm. Genome., 15, 537-543 . PubMed

Kollias G., 2004, "TNF pathophysiology in murine models of chronic inflammation and autoimmunity", Semin Arthritis Rheum., 2005 Apr;34(5 Suppl1), 3-6. Review. PubMed

Redlich K., Gortz B., Hayer S., Zwerina J., Kollias G., Steiner G., Smolen J. S., Schett G., 2004,  "Overexpression of tumor necrosis factor causes bilateral sacroiliitis", Arthritis Rheum., 50 (3), 1001-5 . PubMed

Redlich K., Gortz B., Hayer S., Zwerina J., Doerr N., Kostenuik P., Bergmeister H., Kollias G., Steiner G., Smolen J. S., Schett G., 2004, "Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis", Am. J. Pathol., 164 (2), 543-55 . PubMed

Gortz B., Hayer S., Redlich K., Zwerina J., Tohidast-Akrad M., Tuerk B., Hartmann C., Kollias G., Steiner G., Smolen J. S., Schett G., 2004,  "Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation", J. Bone Miner. Res., 19 (6), 990-8 . PubMed

Douni E., Alexiou M., Kollias G., 2004, "Genetic engineering in the mouse: tuning TNF/TNFR expression", Methods Mol. Med., 98, 137-70 . PubMed

Zwerina J., Hayer S., Tohidast-Akrad M., Bergmeister H., Redlich K., Feige U., Dunstan C., Kollias G., Steiner G., Smolen J., Schett G., 2004, "Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: Effects on synovial inflammation, bone erosion, and cartilage destruction", Arthritis Rheum., 50, 277-90 . PubMed

Douni E., Sfikakis P. P., Haralambous S., Fernandes P., Kollias G., 2004, "Attenuation of inflammatory polyarthritis in TNF transgenic mice by diacerein: comparative analysis with dexamethasone, methotrexate and anti-TNF protocols", Arthritis Res. & Ther., 6 (1), R65-R72 . PubMed

Mershin A., Pavlopoulos E., Fitch O., Braden B. C., Nanopoulos D. V., Skoulakis E., 2004, "Learning and memory deficits upon TAU accumulation of in Drosophila mushroom body neurons", Learning and Memory, 11, 277-287 . PubMed

Nemazanyy I., Panasyuk G., Zhyvoloup A., Panayotou G., Gout I. T., Filonenko V., 2004, "Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism", FEBS Lett., 578, 357-362 . PubMed

Sidera K., Samiotaki M., Yfanti E., Panayotou G., Patsavoudi E., 2004, "Involvement of cell surface HSP90 in cell migration reveals a novel role in the developing nervous system", J. Biol. Chem., 279, 45379-45388 PubMed

Ponnuraj K, Xu Y, Macon K, Moore D, Volanakis JE, Narayana SV. 2004 "Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase ". Mol Cell. 2004 Apr 9;14(1):17-28. PubMed

Panayotou G., 2004, "Molecular analysis of signal transduction pathways", Autoimmun. Rev., 3, S28-9 . PubMed

Foukas L. C., Panayotou G., Shepherd P. R., 2004, "Direct interaction of MHC class II derived peptides with class Ia PI 3-kinase results in dose-dependent stimulatory effects", J. Biol. Chem., 279, 7505-7511. PubMed

2003 - (21)

Kontoyiannis D., 2003, "Cells, genes and pathways in modeled TNF induced IBD",  Arch. Hellenic Med., 20, 54-57.

Luftig M., Prinarakis E., Yasui T., Tsichritzis T., Cahir-McFarland E., Inoue J. I., Nakano H., Mak T. W., Yeh W. C., Li X., Akira S., Suzuki N., Suzuki S., Mosialos G., Kieff E., 2003,  "Epstein-Barr Virus Latent Membrane Protein 1 Activation of NF-κB Through IRAK1 and TRAF6", Proc. Natl. Acad. Sci. U.S.A., 100, 15595-15600 . PubMed

Ye P., Price W., Kassiotis G., Kollias G., D'Ercole A. J., 2003, "Tumor necrosis factor-alpha regulation of insulin-like growth factor-I, type 1 IGF receptor, and IGF binding protein expression in cerebellum of transgenic mice", J. Neurosci. Res., 71, 721-31 . PubMed

Hukkanen M., Platts L. A., Haralambous S., Ainola M., Konttinen Y. T., Kollias G., Polak J. M., 2003, "Induction of Inducible Nitric Oxide Synthase, Argininosuccinate Synthase, and GTP Cyclohydrolase I in Arthritic Joints of Human Tumor Necrosis Factor-a Transgenic Mice", J. Rheumatol., 30, 652-9 . PubMed

Trompouki E., Hatzivassiliou E., Tsichritzis T., Farmer H., Ashworth A., Mosialos G., 2003, "CYLD is a deubiquitinating enzyme that negatively regulates NF-kB activation by TNFR family members", Nature, 424, 793-796 . PubMed

Schett G., Redlich K., Hayer S., Zwerina J., Bolon B., Dunstan C., Gortz B., Schulz A., Bergmeister H., Kollias G., Steiner G., Smolen J. S., 2003, "Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice", Arthritis Rheum., 48, 2042-51 . PubMed

Sfikakis P. P., Kollias G., 2003, "Tumor necrosis factor biology in experimental and clinical arthritis", Curr. Op. Rheumatol., 15, 380-6 . PubMed

Probst H. C., Lagnel J., Kollias G., van den Broek M., 2003, "Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance", Immunity, 18, 713-720 . PubMed

Aidinis V., Plows D., Haralambous S., Armaka M., Papadopoulos P., Kanaki M. Z., Koczan D., Thiessen H. J., Kollias G., 2003, "Functional analysis of an arthritogenic synovial fibroblast", Arthritis Res. & Ther., 5, 140-157 . PubMed

Carninci P., Waki K., Shiraki, Konno H., Shibata K., Itoh M., Aizawa K., Arakawa T., Ishii Y., Sasaki Y., Bono H., Kondo S., Sugahara Y., Saito R., Osato N., Fukuda S., Sato K., Watahiki K., Hirozane-Kishikawa T., Nakamura M., Shibata Y., Yasunishi A., Kikuchi N., Yoshiki A., Kusakabe M., Gustincich S., Beisel K., Pavan W., Aidinis V., Nakagawara A., Held W., Iwata H., Kono T., Nakauchi H., Lyons P., Wells C., Hume D., Fagiolini M., Hensch T., Brinkmeier M., Camper S., Muramatsu M., Okazaki Y., Kawai Y., Hayashizaki Y., 2003,  "Targeting a complex transcriptome: The construction of the mouse full-length cDNA encyclopedia", Genome Res., 13, 1273-89 . PubMed

Akassoglou K., Douni E., Bauer J., Lassmann H., Kollias G., Probert L., 2003, "Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice", Proc. Natl. Acad. Sci. U.S.A., 100, 709-714 . PubMed

Chen H.-K., Fernandez-Funez P., Lam Y. C., Kaytor M. D., Fernandez M. H., Acevedo S. F., Aitken A., Skoulakis E., Orr H. T., Botas J., Zoghbi H. Y., 2003, "Akt phosphorylation-dependent association of ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1", Cell, 113, 457-468 . PubMed

Spilianakis C., Kretsovali A., Agalioti T., Makatounakis T., Thanos D., Papamatheakis J., 2003, "CIITA regulates transcription onset via Ser 5-phosphorylation of RNAPol II", EMBO J., 22, 5125-5136 . PubMed

Dekker S., Toussaint W., Panayotou G., de Wit T., Visser P., Grosveld F., Drabek D., 2003, "Intracellularly expressed single domain antibody prevents the production of porcine retroviruses", J. Virol., 77, 12132-12139  PubMed

Vardakou M., Katapodis P., Samiotaki M., Kekos D., Panayotou G., Christakopoulos P., 2003, "Mode of action of family 10 and 11 endoxylanases on water-unextractable arabinoxylan", Int. J. Biol. Macromol., 33, 129-34 PubMed
 

Staikou E. V., Routsias J. G., Makri A. A., Terzoglou A., Sakarellos-Daitsiotis M., Sakarellos C., Panayotou G., Moutsopoulos H. M., Tzioufas A. G., 2003, "Calreticulin binds preferentially with B cell linear epitopes of Ro60 kD autoantigen, enhancing recognition by anti-Ro60 kD autoantibodies", Clin. Exp. Immunol., 134, 143-50. PubMed

Szalai AJ, Weaver CT, McCrory MA, van Ginkel FW, Reiman RM, Kearney JF, Marion TN, Volanakis JE. 2003, "Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene". Arthritis Rheum. 2003 Jun;48(6):1602-11.  PubMed

Zamanou A., Samiotaki M., Panayotou G., Margaritis L., Lymberi P., 2003, "Fine specificity and subclasses of IgG anti-actin autoantibodies differ in health and disease", J. Autoimm., 20, 333-334. PubMed

Circolo A, Garnier G, Volanakis JE., 2003 " A novel murine complement-related gene encoding a C1r-like serum protein". Mol Immunol. 2003 May;39(14):899-906. PubMed

Garnier G, Circolo A, Xu Y, Volanakis JE., 2003 "Complement C1r and C1s genes are duplicated in the mouse: differential expression generates alternative isomorphs in the liver and in the male reproductive system". Biochem J. 2003 Apr 15;371(Pt 2):631-40. PubMed

Zhu ZB, Volanakis JE., 2003 "Determining alleles of the C2 gene by Southern Blotting". Methods Mol Biol. 2003;210:259-68. PubMed

2002 - (16)

Kontoyiannis D., Boulougouris G., Manoloukos M., Armaka M., Apostolaki M., Pizzaro T., Kotlyarov A., Forster I., Flavell R., Gaestel M., Tsichlis P., Cominelli F., Kollias G., 2002, "Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease",  J. Exp. Med., 196, 1563-74 . PubMed

Redlich K., Hayer S., Ricci R., David J.-P., Tohidast-Akrad M., Kollias G., Steiner G., Smolen G. S., Wagner E. F., Schett G., 2002, "Oscteoclasts are essential for TNF-α-mediated joint destruction", J. Clin. Invest., 110, 1419-1427 . PubMed

Graf D., Nethisinghe S., Palmer D. B., Fisher A. G., Merkenschlager M., 2002, "The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development",  J. Exp. Med., 196 (2), 163-71 . PubMed

Prokova V., Mosialos G., Kardassis D., 2002, "Inhibition of transforming growth factor beta signaling and Smad-dependent activation of transcription by the latent membrane protein 1 of Epstein-Barr virus", J. Biol. Chem., 277, 9342-9350 . PubMed

Redlich K., Hayer S., Maier A., Dunstan C. R., Tohidast-Akrad M., Lang S., Turk B., Pietschmann P., Woloszezuk W., Haralambous S., Kollias G., Steiner G., Smolen J. S., Schett G., 2002, "Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin", Arthritis Rheum., 46, 785-92 . PubMed

Holtmann M. H., Douni E., Schutz M., Zeller G., Mudter J., Lehr H. A., Gerspach J., Scheurich P., Galle P. R., Kollias G., Neurath M. F., 2002, "Tumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn's disease and promotes experimenta colitis in vivo",  Eur. J. Immunol., 32, 3142-51 . PubMed

Kollias G., Kontoyiannis D., 2002, "Role of TNF/TNFR in autoimmunity: specific TNF receptor blockade may be advantageous to anti-TNF treatments", Cytokine Growth Factor Rev., 13, 315-321 . PubMed

Kollias G., Kontoyiannis D., Douni E., Kassiotis G., 2002, "The role of TNF/TNFR in organ-specific and systemic autoimmunity: implications for the design of optimized 'anti-TNF' therapies", Curr. Dir. Autoimmun., 5, 30-50 . PubMed

Hatzivassiliou E., Mosialos G., 2002, "Cellular signalling pathways engaged by the Epstein-Barr virus transforming protein LMP1", Frontiers in Bioscience, 7, 319-329 . PubMed

Agalioti T., Chen G., Thanos D., 2002,  "Deciphering the transcriptional Histone Acetylation Code for a human gene", Cell, 111, 381-392 . PubMed

Arlaud GJ, Gaboriaud C, Garnier G, Circolo A, Thielens NM, Budayova-Spano M, Fontecilla-Camps JC, Volanakis JE. 2002  "Structure, function and molecular genetics of human and murine C1r". Immunobiology. 2002 Sep;205(4-5):365-82. Review. PubMed

Ramadan MA, Shrive AK, Holden D, Myles DA, Volanakis JE, DeLucas LJ, Greenhough TJ. 2002 "The three-dimensional structure of calcium-depleted human C-reactive protein from perfectly twinned crystals". Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):992-1001. Epub 2002 May 29. PubMed

Theodosiou A. ,and Ashworth A., 2002, "MAP kinase phosphatases", Genome Biol., 3(7) , 3009 (1-10) PubMed

Chan T. O., Rodeck U., Chan A. M., Kimmelman A. C., Rittenhouse S. E., Panayotou G., Tsichlis P. N., 2002, "Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit", Cancer Cell, 1, 181-191 PubMed

Gonos E. S., Agrafiotis D., Dontas A. S., Efthimiopoulos S., Galaris D., Karamanos N. K., Kletsas D., Kolettas E., Panayotou G., Pratsinis H., Sekeri-Pataryas K. E., Simoes D., Sourlingas T. G., Stathakos D., Stratigos A. J., Tavernarakis N., Trougakos I. P., Tsiganos C. P., Vynios D. H., 2002, "Ageing research in Greece", Exp. Gerontol., 37 (6), 735-747 . PubMed

Tsukamoto H, Tousson A, Circolo A, Marchase RB, Volanakis JE. 2002  "Calnexin is associated with and induced by overexpressed human complement protein C2". Anat Rec. 2002 May 1;267(1):7-16. PubMed

2001 - (16)

Schett G, Hayer S, Tohidast-Akrad M, Schmid BJ, Lang S, Turk B, Kainberger F, Haralambous S, Kollias G, Newby AC, Xu Q, Steiner G, Smolen J. 2001. Adenovirus-based overexpression of tissue inhibitor of metalloproteinases 1 reduces tissue damage in the joints of tumor necrosis factor alpha transgenic mice. Arthritis Rheum. 2001 Dec;44(12):2888-98. PubMed

Luftig M. A., Cahir-McFarland E., Mosialos G., Kieff E. D., 2001, "Effects of the NIK aly mutation on NF-{kappa}B activation by the Epstein-Barr virus latent infection membrane protein, LT{beta}R, and CD40", J. Biol. Chem., 276, 14602-14606 . PubMed

Kassiotis G., Kollias G., 2001, "Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination", J. Exp. Med., 193, 427-434 . PubMed

Ishii T., Kwon H., Hiscott J., Mosialos G., Koromilas A. E., 2001, "Activation of the IkappaBalpha kinase (IKK) complex by double-stranded RNA-binding defective and catalytic inactive mutants of the interferon-inducible protein kinase PKR", Oncogene, 20, 1900-1912 . PubMed

Neininger A., Kontoyiannis D., Kotlyarov A., Winzen R., Eckert R., Volk H.-D., Holtmann H., Kollias G., Gaestel M., 2001, "MK2 targets AU-rich elements and regulates biosynthesis of Tumor Necrosis Factor and Interleukin-6 independently at different post-transcriptional levels", J. Biol. Chem., 277, 3065-3068 . PubMed

Mosialos G., 2001,  "Cytokine signaling and Epstein-Barr virus-mediated cell transformation", Cytokine Growth Factor Rev., 12, 259-270 . PubMed

Kassiotis G., Kranidioti K., Kollias G., 2001, "Defective CD4T cell priming and resistance to experimental autoimmune encephalomyelitis in TNF-deficient mice due to innate immune hypo-responsiveness",  J. Neuroimmunol., 119, 239-47 . PubMed

Kontoyiannis D., Kotlyarov A., Carballo E., Alexopoulou L., Blackshear P. J., Gaestel M., Davis R., Flavell R., Kollias G., 2001, "Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology", EMBO J., 20, 3760-3770 . PubMed

Bezzi P., Domercq M., Brambilla L., Galli R., Schols D., De Clercq E., Vescovi A., Bagetta G., Kollias G., Meodolesi J., Volterra A., 2001, "CXCR4-activated astrocyte glytamate release via TNFα: amplification by microglia triggers neurotoxicity", Nat. Neurosci., 4, 702-10 . PubMed

Kassiotis G., Kollias G., 2001, "TNF and receptors in organ-specific autoimmune disease: multi-layered functioning mirrored in animal models", J. Clin. Invest., 107, 1507-8 . PubMed

Panayotou G., Ladbury J., 2001, "Analysis of SH2 domain - phosphopeptide interactions by Isothermal Titration Calorimetry and Surface Plasmon Resonance", Methods Mol. Biol., 124, 295-311. PubMed

Xu Y, Ma M, Ippolito GC, Schroeder HW Jr, Carroll MC, Volanakis JE. 2001 "Complement activation in factor D-deficient mice". Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14577-82. Epub 2001 Nov 27. PubMed

Volanakis JE. 2001 "Human C-reactive protein: expression, structure, and function". Mol Immunol. 2001 Aug;38(2-3):189-97. Review. PubMed

Xu Y, Narayana SV, Volanakis JE. 2001 "Structural biology of the alternative pathway convertase". Immunol Rev. 2001 Apr;180:123-35. Review. PubMed

Agrawal A, Shrive AK, Greenhough TJ, Volanakis JE. 2001 "Topology and structure of the C1q-binding site on C-reactive protein". J Immunol. 2001 Mar 15;166(6):3998-4004. PubMed

Szalai AJ, VanCott JL, McGhee JR, Volanakis JE, Benjamin WH Jr. 2001 "Human C-reactive protein is protective against fatal Salmonella enterica serovar typhimurium infection in transgenic mice". Infect Immun. 2000 Oct;68(10):5652-6. PubMed

2000 - (7)

Dumitru C. D., Ceci J. D., Tsatsanis C., Kontoyiannis D., Stamatakis K., Lin J. H., Patriotis C., Jenkins N. A., Copeland N. G., Kollias G., Tsichlis P. N., 2000, "TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent  pathway",  Cell, 103, 1071-1083 . PubMed

Kontoyiannis D., Kollias G., 2000, "Fibroblast biology: Synovial fibroblasts in rheumatoid arthritis: leading role or chorus line?", Arthritis Res., 2, 342-3 . PubMed

Kassiotis George, Pasparakis Manolis, and Kollias George 2000 "Conditional and fixed cytokine gene modification in transgenic and mutant mice" Cytokine Molecular Biology, Practical Approach, Eds. F. Balkwill, Oxford University Press

Szalai AJ, van Ginkel FW, Wang Y, McGhee JR, Volanakis JE. 2000 "Complement-dependent acute-phase expression of C-reactive protein and serum amyloid P-component". J Immunol. 2000 Jul 15;165(2):1030-5. PubMed

Jing H, Xu Y, Carson M, Moore D, Macon KJ, Volanakis JE, Narayana SV. 2000 "New structural motifs on the chymotrypsin fold and their potential roles in complement factor B". EMBO J. 2000 Jan 17;19(2):164-73. PubMed

Zhu Z, Atkinson TP, Hovanky KT, Boppana SB, Dai YL, Densen P, Go RC, Jablecki JS, Volanakis JE. 2000 "High prevalence of complement component C6 deficiency among African-Americans in the south-eastern USA". Clin Exp Immunol. 2000 Feb;119(2):305-10. PubMed

Xu Y, Circolo A, Jing H, Wang Y, Narayana SV, Volanakis JE. 2000 "Mutational analysis of the primary substrate specificity pocket of complement factor B. Asp(226) is a major structural determinant for p(1)-Arg binding". J Biol Chem. 2000 Jan 7;275(1):378-85. PubMed

Szalai AJ, Digerness SB, Agrawal A, Kearney JF, Bucy RP, Niwas S, Kilpatrick JM, Babu YS, Volanakis JE. 2000 "The Arthus reaction in rodents: species-specific requirement of complement". J Immunol. 2000 Jan 1;164(1):463-8. PubMed
 

1999 - (6)

Greagg M. A., Fogg M. J., Panayotou G., Evans S. J., Connolly B. A., Pearl L. H., 1999, "A read-ahead function in archaeal DNA polymerases detects pro-mutagenic template-strand uracil", Proc. Natl. Acad. Sci. U.S.A., 96, 9045-9050 PubMed

Circolo A, Garnier G, Fukuda W, Wang X, Hidvegi T, Szalai AJ, Briles DE, Volanakis JE, Wetsel RA, Colten HR. 1999 "Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA". Immunopharmacology. 1999 May;42(1-3):135-49 PubMed

Szalai AJ, Agrawal A, Greenhough TJ, Volanakis JE. 1999 "C-reactive protein: structural biology and host defense function". Clin Chem Lab Med. 1999 Mar;37(3):265-70. Review. PMID: 10353470 PubMed

Lambris JD, Reid KB, Volanakis JE. 1999 "The evolution, structure, biology and pathophysiology of complement". Immunol Today. 1999 May;20(5):207-11. PubMed

Harpur A. G., Layton M. J., Das P., Bottomley M. J., Panayotou G., Driscoll P. C., Waterfield M. D., 1999, "Intermolecular interactions of the p85 a regulatory subunit of phosphatidylinositol 3-kinase", J. Biol. Chem., 274, 12323-12332 PubMed

Jing H, Macon KJ, Moore D, DeLucas LJ, Volanakis JE, Narayana SV. 1999 "Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D". EMBO J. 1999 Feb 15;18(4):804-14. PubMed

1998 - (1)

Bottomley M. J., Salim K., Panayotou G., 1998, "Phospholipid-binding protein  domains", Biochim. Biophys. Acta, 1436, 165-183 PubMed